Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Lipase-mediated biosynthesis of novel lactose esters. Physicochemical and anticancer studies.

2015/17/D/ST4/00514

Keywords:

sugar esters lipases biocatalysis (R)-3-hydroxyacids cytotoxicity

Descriptors:

  • ST4_12: Photochemistry
  • ST4_11: Coordination and supramolecular chemistry
  • NZ3_3: Apoptosis

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Maciej Guzik 

Number of co-investigators in the project: 4

Call: SONATA 9 - announced on 2015-03-16

Amount awarded: 388 000 PLN

Project start date (Y-m-d): 2016-02-26

Project end date (Y-m-d): 2020-02-25

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw pipet automatycznych (2 szt.) (12 000 PLN)
  2. Stanowisko fermentorowe z wyposażeniem.
  3. Szafa termostatyczna.
  4. Kosz do autoklawu.
  5. Autoklaw (88 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (8)
  1. In search of effective anticancer agents – novel sugar esters based on polyhydroxyalkanoate monomers
    Authors:
    Wojciech Snoch, Dawid Wnuk, Tomasz Witko, Jakub Staroń, Andrzej J. Bojarski, Ewelina Jarek, Francisco J. Plou, Maciej Guzik
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 7238), Wydawca: MDPI
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Influence of Chemical Modifications of Polyhydroxyalkanoate-Derived Fatty Acids on Their Antimicrobial Properties
    Authors:
    Wojciech Snoch, Karolina Stepień, Justyna Prajsnar, Jakub Staroń, Maciej Szaleniec, Maciej Guzik
    Academic press:
    Catalysts (rok: 2019, tom: 9(6), strony: 510), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/catal9060510 - link to the publication
  3. Hollow Silica Microspheres as Robust Immobilization Carriers.
    Authors:
    Wojciech Snoch, Mateusz Tataruch, Olga Zastawny, Ewelina Cichon, Mathilde Gosselin, Hubert Cabana, Maciej Guzi
    Academic press:
    Bioorganic Chemistry (rok: 2019, tom: 93, strony: 102813), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioorg.2019.02.038 - link to the publication
  4. Lactose esters – synthesis and biotechnological applications
    Authors:
    Jakub Staroń, Janusz M. Dąbrowski, Ewelina Cichoń, Maciej Guzik
    Academic press:
    Critical Reviews in Biotechnology (rok: 2018, tom: 2, strony: 245-258), Wydawca: Taylor and Francis
    Status:
    Published
    DOI:
    10.1080/07388551.2017.1332571 - link to the publication
  1. Novel halogenated sugar esters derived from bacterial polymer polyhydroxyalkanoate
    Authors:
    W.Snoch, J.Staroń and M. Guzik
    Conference:
    NanoTech Poland 2017 (rok: 2017, ), Wydawca: Collegium Physicum, Adam Mickiewicz University in Poznań
    Data:
    konferencja 01-03/06/2017
    Status:
    Published
  2. Polyhydroxyalkanoates: Bacterial polymers for biomedical applications
    Authors:
    Maciej Guzik
    Conference:
    International Conference on Catalysis and Surface Chemistry (rok: 2018, ), Wydawca: IKIFP PAN
    Data:
    konferencja 18-23.03
    Status:
    Published
  3. Chemo-biotechnological synthesis of precursors for biocatalytic acylation of sugars
    Authors:
    Jakub Staron, Ewelina Cicho, Matylda Stefaniak, Maciej Guzik
    Conference:
    17th European Congres on Biotechnology (rok: 2016, ), Wydawca: Elsevier/ New Biotechnology
    Data:
    konferencja 3-6/07/2016
    Status:
    Published
  4. Polyhydroxyalkanoates – Bacterial Polymers for Biomedical Applications
    Authors:
    Maciej Guzik, Kamila Sofińska, Katarzyna Haraźna, Wojciech Snoch,Tomasz Witko, Daria Solarz, Karolina Stępień, Jakub Staroń
    Conference:
    Resolution of Inflammation, Infection and Tissue Regeneration (rok: 2018, ), Wydawca: The New York Academy of Sciences
    Data:
    konferencja 25-26.06
    Status:
    Published
  5. Bacterially derived chiral synthons
    Authors:
    J. Prajsnar, M.Witko, A. Bojarski, J. Staroń, M. Guzik
    Conference:
    Symposium on biotransformations for pharmaceutical and cosmetic industry (rok: 2018, ), Wydawca: Uniwersytet Wrocławski
    Data:
    konferencja 25-27/07
    Status:
    Published
  6. Effect of lipase immobilization process on the enzymatic synthesis of new sugar esters with potential applications in food and pharmaceutical industries
    Authors:
    Wojciech Snoch, Ewelina CICHOŃ, Maciej Guzik
    Conference:
    Symposium on biotransformations for pharmaceutical and cosmetic industry (rok: 2018, ), Wydawca: Uniwersytet Wrocławski
    Data:
    konferencja 25-27/07
    Status:
    Published
  7. Enzymatic synthesis of lactose esters using modified monomers originating from bacterial polyhydroxyalkanoates for applications in food and medical industries
    Authors:
    W. Snoch, J. Staroń, M. Guzik
    Conference:
    International Conference on Catalysis and Surface Chemistry (rok: 2018, ), Wydawca: IKIFP PAN
    Data:
    konferencja 18-23.03
    Status:
    Published
  8. Reverting chirality of bacterially synthesised pro-drugs
    Authors:
    J. Prajsnar, M. Witko, A. Bojarski, M. Guzik
    Conference:
    International Conference on Catalysis and Surface Chemistry (rok: 2018, ), Wydawca: IKIFP PAN
    Data:
    konferencja 18-23.03
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy