Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Biological function of the molecular chaperone ClpB (Hsp100) from the bacterium Leptospira interrogans, the etiologic agent of leptospirosis

2015/17/N/NZ6/03493

Keywords:

ClpB molecular chaperone leptospirosis pathogen

Descriptors:

  • NZ6_4: Bacteriology
  • NZ6_3: Animal immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Joanna Krajewska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 149 800 PLN

Project start date (Y-m-d): 2016-01-20

Project end date (Y-m-d): 2019-01-19

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikrowirówka z systemem chłodzącym i rotorem (Eppendorff) (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (5)
  1. Immunoreactivity of the AAA+ chaperone ClpB from Leptospira interrogans with sera from Leptospira-infected animals
    Authors:
    Joanna Krajewska, Zbigniew Arent, Daniel Więckowski, Michal Zolkiewski, Sabina Kędzierska-Mieszkowska
    Academic press:
    BMC Microbiology (rok: 2016, tom: 16, strony: 151), Wydawca: BioMed Central The Open Access Publisher
    Status:
    Published
    DOI:
    10.1186/s12866-016-0774-8 - link to the publication
  2. Characterization of the molecular chaperone ClpB from the pathogenic spirochaete Leptospira interrogans
    Authors:
    Joanna Krajewska, Anna Modrak-Wójcik,Zbigniew J. Arent, Daniel Więckowski, Michal Zolkiewski, Agnieszka Bzowska, Sabina Kędzierska-Mieszkowska
    Academic press:
    PLoS One (rok: 2017, tom: 12, strony: 45312), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0181118 - link to the publication
  3. Isolation and identification of putative protein substrates of the AAA+ molecular chaperone ClpB from the pathogenic spirochaete
    Authors:
    Joanna Krajewska, Zbigniew Arent, Michal Zolkiewski, Sabina Kedzierska-Mieszkowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2018, tom: 19, strony: 1234), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19041234 - link to the publication
  1. Identification of putative protein substrates for the molecular chaperone ClpB in the pathogenic bacterium Leptospira interrogans
    Authors:
    Joanna Krajewska, Zbigniew Arent, Daniel Więckowski, Sabina Kędzierska-Mieszkowska
    Conference:
    X Parnas Conference Young Scientist Forum "Molecules in the Living Cell and Innovative Medicine" (rok: 2016, ), Wydawca: Acta Biochemica Polonica
    Data:
    konferencja 10-12.07.2016
    Status:
    Published
  2. Trapping and identification of potential substrates of the molecular chaperone ClpB (Hsp100) from the pathogenic bacterium Leptospira interrogans
    Authors:
    Joanna Krajewska, Zbigniew Arent, Sabina Kędzierska-Mieszkowska
    Conference:
    3rd ELS Scientific Meeting on leptospirosis and other rodent borne haemorrhagic fevers (rok: 2018, ), Wydawca: Nuova Stampa Color srl
    Data:
    konferencja 24-26.05.2018
    Status:
    Published
  3. Charakterystyka białka opiekuńczego ClpB (Hsp100) pochodzącego z patogennej bakterii Leptospira interrogans, czynnika etiologicznego leptospirozy
    Authors:
    Joanna Krajewska, Zbigniew Arent, Anna Modrak-Wójcik, Daniel Więckowski, Agnieszka Bzowska, Sabina Kędzierska-Mieszkowska
    Conference:
    I Ogólnopolska Mikrobiologiczna Konferencja Naukowa Microbs (rok: 2016, ), Wydawca: Fundacja na rzecz promocji nauki i rozwoju Tygiel
    Data:
    konferencja 12-13.05.2016
    Status:
    Published
  4. A proteomic approach for screening potential substrates of the molecular chaperone ClpB from Leptospira interrogans
    Authors:
    Joanna Krajewska, Zbigniew Arent, Sabina Kędzierska-Mieszkowska
    Conference:
    I Konferencja - Naukowa Jesień w UCMW "Infekcyjne czynniki etiologiczne XXI wieku-wspólny problem ludzi i zwierząt" (rok: 2017, ), Wydawca: Wydawnictwo Uniwersytetu Rolniczego w Krakowie
    Data:
    konferencja 29-30.09.2017
    Status:
    Published
  5. Rola dezagregazy ClpB w wirulencji patogenów bakteryjnych
    Authors:
    Joanna Krajewska, Zbigniew Arent, Sabina Kędzierska-Mieszkowska
    Conference:
    II Ogólnopolska Mikrobiologiczna Konferencja Naukowa Microbs (rok: 2017, ), Wydawca: Fundacja na rzecz promocji nauki i rozwoju TYGIEL
    Data:
    konferencja 18-19.04.2017
    Status:
    Published