Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Energetic constraints on information processing and storing in the nervous system.

2015/17/B/NZ4/02600

Keywords:

Computational Neuroscience brain information metabolism synapses plasticity constraints Neuroinformatics

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ2_10: Biological systems analysis, modelling and simulation
  • NZ2_8: Computational biology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jan Karbowski 

Number of co-investigators in the project: 4

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 385 100 PLN

Project start date (Y-m-d): 2016-02-26

Project end date (Y-m-d): 2019-09-25

Project duration:: 43 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. laptop (3 500 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Deciphering neural circuits for Caenorhabditis elegans behavior by computations and perturbations to genome and connectome
    Authors:
    J. Karbowski
    Academic press:
    Current Opinion in Systems Biology (rok: 2019, tom: 13, strony: 44-51), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.coisb.2018.09.008 - link to the publication
  2. Energetics of stochastic BCM type synaptic plasticity and storing of accurate information
    Authors:
    Jan Karbowski
    Academic press:
    Journal of Computational Neuroscience (rok: 2021, tom: 49, strony: 13150), Wydawca: Springer-Nature
    Status:
    Published
    DOI:
    10.1007/s10827-020-00775-0 - link to the publication
  3. Metabolic constraints on synaptic learning and memory
    Authors:
    J. Karbowski
    Academic press:
    Journal of Neurophysiology (rok: 2019, tom: 122, strony: 1473-1490), Wydawca: American Physiological Society
    Status:
    Published
    DOI:
    10.1152/jn.00092.2019 - link to the publication
  4. Optimal synaptic signaling connectome for locomotory behavior in C. elegans: design minimizing energy cost
    Authors:
    F. Rakowski, J. Karbowski
    Academic press:
    PloS Comput Biol (rok: 2017, tom: 13, strony: e1005834), Wydawca: Public Library of Science, San Francisco
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1005834 - link to the publication
  5. Synaptic games and learning in the framework of nonequilibrium thermodynamics
    Authors:
    Jan Karbowski
    Academic press:
    Journal of Computational Neuroscience , Wydawca: Springer-Nature
    Status:
    Submitted
  6. The cost of information encoded in the proteins of postsynaptic density
    Authors:
    Jan Karbowski
    Academic press:
    Journal of Computational Neuroscience , Wydawca: Springer-Nature
    Status:
    Submitted
  7. Distribution of metabolic energy per neuron and per synapse across cerebral cortex
    Authors:
    Jan Karbowski
    Academic press:
    Cerebral Cortex , Wydawca: Oxford Univ. Press
    Status:
    Submitted