Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Energetic constraints on information processing and storing in the nervous system.

2015/17/B/NZ4/02600

Keywords:

Computational Neuroscience brain information metabolism synapses plasticity constraints Neuroinformatics

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ2_10: Biological systems analysis, modelling and simulation
  • NZ2_8: Computational biology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jan Karbowski 

Number of co-investigators in the project: 4

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 385 100 PLN

Project start date (Y-m-d): 2016-02-26

Project end date (Y-m-d): 2019-09-25

Project duration:: 43 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. laptop (3 500 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Optimal synaptic signaling connectome for locomotory behavior in C. elegans: design minimizing energy cost
    Authors:
    F. Rakowski, J. Karbowski
    Academic press:
    PloS Comput Biol (rok: 2017, tom: 13, strony: e1005834), Wydawca: Public Library of Science, San Francisco
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1005834 - link to the publication
  2. Distribution of metabolic energy per neuron and per synapse across cerebral cortex
    Authors:
    Jan Karbowski
    Academic press:
    Cerebral Cortex , Wydawca: Oxford Univ. Press
    Status:
    Submitted
  3. Deciphering neural circuits for Caenorhabditis elegans behavior by computations and perturbations to genome and connectome
    Authors:
    J. Karbowski
    Academic press:
    Current Opinion in Systems Biology (rok: 2019, tom: 13, strony: 44-51), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.coisb.2018.09.008 - link to the publication
  4. Metabolic constraints on synaptic learning and memory
    Authors:
    J. Karbowski
    Academic press:
    Journal of Neurophysiology (rok: 2019, tom: 122, strony: 1473-1490), Wydawca: American Physiological Society
    Status:
    Published
    DOI:
    10.1152/jn.00092.2019 - link to the publication
  5. Synaptic games and learning in the framework of nonequilibrium thermodynamics
    Authors:
    Jan Karbowski
    Academic press:
    Journal of Computational Neuroscience , Wydawca: Springer-Nature
    Status:
    Submitted
  6. Energetics of stochastic BCM type synaptic plasticity and storing of accurate information
    Authors:
    Jan Karbowski
    Academic press:
    Journal of Computational Neuroscience (rok: 2021, tom: 49, strony: 13150), Wydawca: Springer-Nature
    Status:
    Published
    DOI:
    10.1007/s10827-020-00775-0 - link to the publication
  7. The cost of information encoded in the proteins of postsynaptic density
    Authors:
    Jan Karbowski
    Academic press:
    Journal of Computational Neuroscience , Wydawca: Springer-Nature
    Status:
    Submitted