beta-Lactam analogues of antiviral oxetanocins

2015/17/B/ST5/00076

Keywords

Descriptors

  • ST5_23: Chemia organiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny, Katedra Chemii Bioorganicznej i Biokoordynacyjnej, Zakład Chemii Bioorganicznej

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Dorota Gabriela Piotrowska

Number of co-investigators in the project: 4

Call

OPUS 9 – announced on 2015-03-16

Amount awarded
324 000 PLN
Project start date
2016-01-19
Project end date
2020-01-18
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. reaktor ciśnieniowy do reakcji w małej skali umożliwiający pełną kontrolę wszystkich parametrów. Cost: 60 000 PLN
  2. termostat.

Information in the final report

Publication in academic press/journals (4)

  1. Design, Synthesis and the Biological Evaluation of a New Series of Acyclic 1,2,3-Triazole Nucleosides

    Authors:
    Iwona E. Głowacka, Graciela Andrei, Dominique Schols, Robert Snoeck, Katarzyna Gawron
    Academic press:
    Archiv der Pharmazie. Chemistry in Life Sciences (year: 2017, volume: 350, pages: 1-17 (e1700166)), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/ardp.201700166 – link to the publication
  2. Novel N-Substituted 3-Aryl-4-(diethoxyphosphoryl)azetidin-2-ones as Antibiotic Enhancers and Antiviral Agents in Search for a Successful Treatment of Complex Infections

    Authors:
    Iwona E. Głowacka, Magdalena Grabkowska-Drużyc, Graciela Andrei, Dominique Schols, Robert Snoeck, Karolina Witek, Sabina Podlewska, Jadwiga Handzlik, Dorota G. Piotrowska
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 8032), Publisher: Multidisciplinary Digital Publishing Institute (MPDI)
    Status:
    Published
    DOI:
    10.3390/ijms22158032 – link to the publication
  3. Synthesis and Neuroprotective Properties of N-Substituted C-Dialkoxyphosphorylated Nitrones

    Authors:
    Dorota G. Piotrowska, Laura Mediavilla, Leticia Cuarental, Iwona E. Głowacka, Jose Marco-Contelles, Dimitra Hadjipavlou-Litina, Francisco Lopez-Munoz and Maria Jesus Oset-Gasque
    Academic press:
    ACS Omega (year: 2019, volume: 4, pages: 8581-8587), Publisher: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acsomega.9b00189 – link to the publication
  4. β-LACTAM ANALOGUES OF OXETANOCINS – SYNTHESIS AND BIOLOGICAL ACTIVITY

    Authors:
    Iwona E. Głowacka, Magdalena Grabkowska-Drużyc, Liwia Lebelt, Graciela Andrei, Dominique Schols, Robert Snoeck, Dorota G. Piotrowska
    Status:
    Accepted for publication

Book publications / chapters in book publications (2)

  1. -

    Authors:
    Magdalena Łysakowska, Iwona Głowacka, Dorota Piotrowska
    Book:
    POCHODNE CHINAZOLINO-2,4-DIONU – SYNTEZA I AKTYWNOŚĆ BIOLOGICZNA (year: 2021, volume: 1, pages: 16803), Publisher: Wydawnictwo Uniwersytetu Medycznego w Łodzi
    Status:
    Published
  2. -

    Authors:
    Iwona Rozpara, Iwona E. Głowacka, Dorota G. Piotrowska
    Book:
    SYNTEZA FOSFORYLOWANYCH NITRONÓW ORAZ ICH ZASTOSOWANIA (year: 2021, volume: 10, pages: 16438), Publisher: Wydawnictwo Uniwersytetu Medycznego w Łodzi
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski