Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of polysialic acid in modulation of biophysical properties of plasma membrane in cancer cells

2015/17/N/NZ1/00029

Keywords:

polysialic acid cancer cells plasma membrane

Descriptors:

  • NZ1_3: Biophysics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Opolski, Wydział Przyrodniczo-Techniczny

woj. opolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Karolina Sapoń 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 99 984 PLN

Project start date (Y-m-d): 2016-02-22

Project end date (Y-m-d): 2018-02-21

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Transiluminator ze światłem białym (3 567 PLN)
  2. Oprogramowanie:Microsoft Office Professional 2013 32-bit/x64 Medialess (720 PLN)
  3. zasilacz do elektroforezy (1 800 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (1)
  1. Polysialic acid chains exhibit enhanced affinity for ordered regions of membranes
    Authors:
    Sapoń Karolina, Janas Teresa, Sikorski Aleksander F., Janas Tadeusz
    Academic press:
    Biochimica et Biophysica Acta-Biomembranes (rok: 2019, tom: 1861, strony: 245-255), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2018.07.008 - link to the publication
  2. Exosome-associated polysialic acid modulates membrane potentials, membrane thermotropic properties, and raft-dependent interactions between vesicles
    Authors:
    Karolina Sapoń, Iga Gawrońska, Teresa Janas, Aleksander F. Sikorski, Tadeusz Janas
    Academic press:
    FEBS Letters (rok: 2020, ), Wydawca: FEBS Press
    Status:
    Submitted
  1. Biophysical Characterization of Polysialic Acid—Membrane Nanosystems
    Authors:
    Sapoń Karolina, Janas Teresa, Janas Tadeusz
    Book:
    Series in BioEngineering: Thermodynamics and Biophysics of Biomedical Nanosystems Applications and Practical Considerations (rok: 2019, tom: 4, strony: 365-396), Wydawca: Springer Nature
    Status:
    Published