Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of polysialic acid in modulation of biophysical properties of plasma membrane in cancer cells

2015/17/N/NZ1/00029

Keywords:

polysialic acid cancer cells plasma membrane

Descriptors:

  • NZ1_3: Biophysics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Opolski, Wydział Przyrodniczo-Techniczny

woj. opolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Karolina Sapoń 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 99 984 PLN

Project start date (Y-m-d): 2016-02-22

Project end date (Y-m-d): 2018-02-21

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Transiluminator ze światłem białym (3 567 PLN)
  2. Oprogramowanie:Microsoft Office Professional 2013 32-bit/x64 Medialess (720 PLN)
  3. zasilacz do elektroforezy (1 800 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (1)
  1. Exosome-associated polysialic acid modulates membrane potentials, membrane thermotropic properties, and raft-dependent interactions between vesicles
    Authors:
    Karolina Sapoń, Iga Gawrońska, Teresa Janas, Aleksander F. Sikorski, Tadeusz Janas
    Academic press:
    FEBS Letters (rok: 2020, ), Wydawca: FEBS Press
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Polysialic acid chains exhibit enhanced affinity for ordered regions of membranes
    Authors:
    Sapoń Karolina, Janas Teresa, Sikorski Aleksander F., Janas Tadeusz
    Academic press:
    Biochimica et Biophysica Acta-Biomembranes (rok: 2019, tom: 1861, strony: 245-255), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2018.07.008 - link to the publication
  1. Biophysical Characterization of Polysialic Acid—Membrane Nanosystems
    Authors:
    Sapoń Karolina, Janas Teresa, Janas Tadeusz
    Book:
    Series in BioEngineering: Thermodynamics and Biophysics of Biomedical Nanosystems Applications and Practical Considerations (rok: 2019, tom: 4, strony: 365-396), Wydawca: Springer Nature
    Status:
    Published

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