Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of HAX-1 protein in induction of pro-inflammatory responce of cancer cells.

2015/17/N/NZ1/00668

Keywords:

HAX-1 MCPIP1 interaction inflammation ccRCC

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ1_11: Other related subjects

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ewelina Macech-Klicka 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2016-03-25

Project end date (Y-m-d): 2019-09-24

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. 0.
  2. pipetus - pipeta wielkoobjetosciowa do hodowli komórkowych (2 000 PLN)
  3. kołyska laboratoryjna (1 860 PLN)
  4. pipeta elektroniczna (2 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. The RNA-Binding Landscape of HAX1 Protein Indicates Its Involvement in Translation and Ribosome Assembly
    Authors:
    A. Balcerak,E. Macech-Klicka,M.Wakula, R. Tomecki, K. Goryca, M. Rydzanicz,M. Chmielarczyk,M. Szostakowska-Rodzos,M. Wisniewska,F. Lyczek,A. Helwak,D. Tollervey,G. Kudla, E.A. Grzybowska
    Academic press:
    Cells (rok: 2022, tom: 11, strony: 45313), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11192943 - link to the publication
  1. The role of HAX-1 and MCPIP proteins in regulation of transcripts involved in pro-inflammatory response of cancer cells
    Authors:
    E. Macech-Klicka, E. Sarnowska, N. Rusetska, A. Chrzan, M. Ligaj, M. Szymański, T. Demkow, E. Grzybowska, J. A. Siedlecki
    Conference:
    BIO2018 Congress and 51st Meeting of the Polish Biochemical Society (rok: 2018, ), Wydawca: ACTA BIOCHIMICA POLONICA
    Data:
    konferencja 18-21.09.2018
    Status:
    Published
  2. The impact of HAX-1 protein on regulation of transcripts involved in pro-inflammatory response of cancer cells
    Authors:
    Ewelina Macech-Klicka, Elzbieta Sarnowska, Nataliia Rusetska, Alicja Chrzan, Marcin Ligaj, Michal Szymanski, Tomasz Demkow, Ewa Grzybowska, Janusz A. Siedlecki
    Conference:
    The 24th Annual Meeting of the RNA Society (rok: 2019, ), Wydawca: The RNA Society
    Data:
    konferencja 11-16.06.2019
    Status:
    Published
  3. The role of HAX1 and MCPIP proteins in regulation of transcripts involved in proinflammatory response of cancer cells
    Authors:
    Ewelina Macech-Klicka, Elzbieta Sarnowska , Nataliia Rusetska , Alicja Chrzan, Marcin Ligaj, Michal Szymanski, Ewa Grzybowska, Janusz A. Siedlecki
    Conference:
    RNA 2017 Then 22nd Annual Meeting of the RNA Society (rok: 2017, ), Wydawca: The RNA Society
    Data:
    konferencja 30.05-03.06.2017
    Status:
    Published