Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New insights into the role of mixed biofilms with the participiation of Candida albicans in the development of periodontal disease.

2015/17/B/NZ6/02078

Keywords:

fungal infection bacterial infection C. albicans P. gingivalis

Descriptors:

  • NZ6_7: Mycology
  • NZ6_4: Bacteriology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Maria Rąpała-Kozik 

Number of co-investigators in the project: 6

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 396 000 PLN

Project start date (Y-m-d): 2016-02-12

Project end date (Y-m-d): 2018-09-11

Project duration:: 31 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Uniwersalna, szybkoobrotowa wirówka laboratoryjna z chłodzeniem, z wymiennymi rotorami, (35 000 PLN)
  2. szafowa zamrażarka niskotemperaturowa (-80C) (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  • Book publications / chapters in book publications (1)
  1. Candida albicans Shields the Periodontal Killer Porphyromonas gingivalis from Recognition by the Host Immune System and Supports the Bacterial Infection of Gingival Tissue
    Authors:
    Dominika Bartnicka, Miriam Gonzalez-Gonzales, Joanna Sykut, Joanna Koziel, Izabela Ciaston2, Karina Adamowicz, Grazyna Bras, Marcin Zawrotniak1, Justyna Karkowska-Kuleta, Dorota Satala, Andrzej Kozik, Edyta Zyla, Katarzyna Gawron, Katarzyna Lazarz-Bartyzel, Maria Chomyszyn-Gajewska and Maria Rapala-Kozik*
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(6), strony: 1984), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21061984. - link to the publication
  2. Peptidylarginine deiminase of Porphyromonas gingivalis modulates the interactions between mixed fungal-bacterial biofilm and host proteins
    Authors:
    Justyna Karkowska-Kuleta, Magdalena Surowiec , Mariusz Gogól , Joanna Kozieł , Barbara Potempa, Jan Potempa, Andrzej Kozik and Maria Rąpała-Kozik *
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(7), strony: 2495), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21072495 - link to the publication
  3. Adhesive protein-mediated cross-talk between Candida albicans and Porphyromonas gingivalis in dual species biofilm protects the anaerobic bacterium in unfavorable oxic environment
    Authors:
    Dominika Bartnicka, Justyna Karkowska-Kuleta, Marcin Zawrotniak, Dorota Satała, Kinga Michalik, Gabriela Zielinska, Oliwia Bochenska, Andrzej Kozik, Izabela Ciaston, Joanna Koziel, Lindsay C. Dutton, Angela H. Nobbs, Barbara Potempa, Zbigniew Baster, Zenon Rajfur, Jan Potempa, Maria Rapala-Kozik
    Academic press:
    Scientific Reports (rok: 2019, tom: 9, strony: 4376), Wydawca: Nature Research Journals
    Status:
    Published
    DOI:
    10.1038/s41598-019-40771-8 - link to the publication
  4. The activity of bacterial peptidylarginine deiminase is important during formation of dual-species biofilm by periodontal pathogen Porphyromonas gingivalis and opportunistic fungus Candida albicans
    Authors:
    Karkowska-Kuleta Justyna, Dominika Bartnicka, Marcin Zawrotniak, Gabriela Zielinska, Anna Kierońska, Oliwia Bochenska, Izabela Ciaston Joanna Koziel, Jan Potempa, Zbigniew Baster, Zenon Rajfur, Maria Rapala-Kozik,*
    Academic press:
    Pathogens and Disease (rok: 2018, tom: 76, strony: fty033), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/femspd/fty033 - link to the publication
  1. Biofilm formation between fungal oportunist- Candida albicans ang gingiva pathogen -Phorphyromonas gingivalis
    Authors:
    D. Ostrowska, Zielińska G., Karkowska-Kuleta, A. Kierońska, I. Główczyk, J. Kozieł, M. Rąpała-Kozik
    Conference:
    XLIV Winter School Faculty of Biochemistry, Biophysics and Biotechnology (rok: 2017, ), Wydawca: Jagiellonian University in Kraków
    Data:
    konferencja 14-18 luty
    Status:
    Published
  2. Candida albicans protects anaerobial bacteria in mixed species biofilm
    Authors:
    Ostrowska D., Zielińska G., Karkowska-Kuleta J., Kierońska A., Glowczyk I., Proba A., Zawrotniak M., Koziel J., Rapala-Kozik M.
    Conference:
    Eurobiofilms 2017 (V European Congress on Microbial Biofilms) (rok: 2017, ), Wydawca: European Society of Clinical Microbiology and Infectious Diseases
    Data:
    konferencja 19-22.09.
    Status:
    Published
  3. Porphyromonas gingivalis uses citrullination in mixed species biofilms
    Authors:
    J. Karkowska-Kuleta, D. Ostrowska, G. Zielińska, A. Kierońska, I. Glowczyk, M. Zawrotniak, O. Bocheńska, J. Koziel, M. Rapala-Kozik
    Conference:
    Eurobiofilms 2017 (V European Congress on Microbial Biofilms) (rok: 2017, ), Wydawca: European Society of Clinical Microbiology and Infectious Diseases
    Data:
    konferencja 19-22.09.
    Status:
    Published
  4. Cell surface enolase of Candida species is involved in the interactions with human host and the formation of polymicrobial biofilms
    Authors:
    M. Rapala-Kozik, J. Karkowska-Kuleta, D. Satala, M. Gogol, D. Bartnicka, M. Zawrotniak, A. Kozik
    Conference:
    20th Congress of the International Society for Human and Animal Mycology (rok: 2018, ), Wydawca: ISHAM
    Data:
    konferencja 30.06.-4.07.
    Status:
    Published
  5. Human Gingival Fibroblasts from Patients Infected with Periodontal Pathogens are Less Sensitive to Candida albicans Infection
    Authors:
    Rapala-Kozik M., Ostrowska D., Sykut J., Bochenska O., Karkowska-Kuleta J., Seweryn K., Kozik A
    Conference:
    Microbe 2016 (rok: 2016, ), Wydawca: ASM
    Data:
    konferencja 16-20 czerwca
    Status:
    Published
  1. Interactions of Candida albicans Cells with Aerobic and Anaerobic Bacteria during Formation of Mixed Biofilms in the Oral Cavity
    Authors:
    M. Rapala-Kozik, M. Zawrotniak, M. Gogol, D. Bartnicka, D. Satala, M. Smolarz, J. Karkowska-Kuleta, A. Kozik
    Book:
    Candida albicans (rok: 2019, tom: 43556, strony: 119-142), Wydawca: IntechOpen ISBN 978-953-51-6399-2
    Status:
    Published

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