Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Pyrene-functionalized molecular sensors consisting of two integrated domains: an i-motif and hairpin.

2015/17/B/ST4/03627

Keywords:

molecular sensor i-motif molecular beacon fluorescence pyrene excimer pH

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_6: Instrumental methods in chemistry
  • NZ1_3: Biophysics

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Bernard Juskowiak 

Number of co-investigators in the project: 7

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 868 000 PLN

Project start date (Y-m-d): 2016-01-19

Project end date (Y-m-d): 2020-01-18

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Automatyczna płuczka do mikropłytek typu HydroSpeed™ (21 000 PLN)
  2. Spektrometr CD z jedostką sterującą oraz przystawką termostatującą typu Peltiera chłodzoną cyrkulatorem wodnym (434 000 PLN)
  3. stacja do obrobki danych (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (8)
  1. Studying the influence of stem composition in pH-sensitive molecular beacons onto their sensing properties
    Authors:
    Anna Dembska, Elzbieta Kierzek, Bernard Juskowiak
    Academic press:
    Analytica Chimica Acta (rok: 2017, tom: 990, strony: 157-167), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.aca.2017.07.040 - link to the publication
  2. Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences"
    Authors:
    Dembska, A.; Switalska, A.; Fedoruk-Wyszomirska, A.; Juskowiak, B.
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 11006), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-020-67745-5 - link to the publication
  3. pH-Sensing fluorescence oligonucleotide probes based on an i-motif scaffold: a review
    Authors:
    Anna Dembska, Patrycja Bielecka, Bernard Juskowiak
    Academic press:
    Analytical Methods (rok: 2017, tom: 9, strony: 6092-6106), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c7ay01942d - link to the publication
  4. The analytical and biomedical potential of cytosine-rich oligonucleotides: A review
    Authors:
    A. Dembska
    Academic press:
    Analytica Chimica Acta (rok: 2016, tom: 930, strony: 45303), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.aca.2016.05.007 - link to the publication
  5. Spectroscopic studies upon chimeric molecular beacons with i-motif forming sequence in the loop."
    Authors:
    Dembska, A.; Masternak, J.;Prochota, M.
    Academic press:
    Journal of Molecular Structure (rok: 2020, tom: 1217, strony: 128436), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2020.128436 - link to the publication
  1. Molecular beacons dedicated to pH sensing
    Authors:
    A. Dembska, P. Bielecka, B. Juskowiak
    Conference:
    XVI Conference of the Polish Biophysical Society in Ryn (rok: 2016, ), Wydawca: Adam Mickiewicz University, Faculty of Physics,DE GRUYTER OPEN
    Data:
    konferencja June 28 – July 1, 2016
    Status:
    Published
    DOI:
    link to the publication
  2. Pyrene-functionalized molecular beacon with i-motif in the loop synthesized via catalyst-free click chemistry
    Authors:
    J. Masternak, A. Dembska, B. Juskowiak
    Conference:
    44th International Conference of SSCHE (rok: 2017, ), Wydawca: ISBN: 978-80-89597-58-1, EAN: 9788089597581
    Data:
    konferencja Maj 22–26, 2017
    Status:
    Published
  3. Spectral properties of molecular beacons with pyrene-labeled i-motif in the loop
    Authors:
    M. Prochota, A. Dembska, B. Juskowiak
    Conference:
    45th International Conference of of SSCHE (rok: 2018, ), Wydawca: ISBN: 978-80-89597-89-5, EAN: 9788089597895
    Data:
    konferencja maj 21-25, 2018
    Status:
    Published
  4. THE MOLECULAR BEACONS FOR BIOANALYTICAL APPLICATIONS
    Authors:
    A. Dembska , P. Bielecka, B. Juskowiak
    Conference:
    XVII Conference of the Polish Biophysical Society in Olsztyn (rok: 2019, ), Wydawca: Adam Mickiewicz University, Faculty of Physics,DE GRUYTER OPEN
    Data:
    konferencja 24-27 June
    Status:
    Published
  5. Charakterystyka spektroskopowa latarni molekularnej z i-motywem w pętli oraz 5-(1etynylopienylo)-2'-deoksyurydyną w rdzeniu
    Authors:
    M. Prochota, A. Dembska, B. Juskowiak
    Conference:
    "Nauka i przemysł lubelskie spotkania studenckie" (rok: 2018, ), Wydawca: UMCS Lublin
    Data:
    konferencja 25 czerwca 2018
    Status:
    Published
  6. Pyrene excimer signaling molecular beacon synthesized via strain-promoted alkyne–azide cycloaddition
    Authors:
    J. Masternak, A. Dembska, B. Juskowiak
    Conference:
    45th International Conference of of SSCHE (rok: 2018, ), Wydawca: ISBN: 978-80-89597-89-5, EAN: 9788089597895
    Data:
    konferencja maj 21-25, 2018
    Status:
    Published
  7. Charakterystyka spektroskopowa latarni molekularnej z i-motywem w pętli do pomiaru pH
    Authors:
    J. Masternak, A. Dembska, B. Juskowiak
    Conference:
    "Nauka i przemysł lubelskie spotkania studenckie" (rok: 2017, ), Wydawca: UMCS Lublin
    Data:
    konferencja 20 czerwca 2017
    Status:
    Published
  8. I-motif folding studied by fluorescence correlation spectroscopy
    Authors:
    A. Dembska,P. Bielecka,J.Gapinski, E. Banachowicz, B. Juskowiak
    Conference:
    43rd International Conference of the Slovak Society of Chemical Engineering (rok: 2016, ), Wydawca: ISBN: 978-80-89597-35-2, EAN: 9788089597352
    Data:
    konferencja Maj 23–27, 2016
    Status:
    Published

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