Effect of indoxyl sulfate on modulating the activity of hemostasis and hemodynamic parameters in animal model of experimental arterial thrombosis.
2015/17/N/NZ4/02334
Keywords
Descriptors
- NZ4_4: Patofizjologia ogólna
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej
Voivodeship: podlaskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 9 – announced on 2015-03-16
- Amount awarded
- 150 000 PLN
- Project start date
- 2016-03-16
- Project end date
- 2019-03-15
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
The uremic toxin indoxyl sulfate accelerates thrombotic response after vascular injury in animal models.
- Authors:
- Małgorzata Karbowska, Tomasz Kamiński, Natalia Marcińczyk, Tomasz Misztal, Tomasz Rusak, Łukasz Smyk, Dariusz Pawlak.
- Academic press:
- Toxins (year: 2017, volume: 9, pages: 229 wersja elektroniczna), Publisher: MDPI Switzerland
- Status:
- Published
- DOI:
- 10.3390/toxins9070229 – link to the publication
-
Indoxyl Sulfate Promotes Arterial Thrombosis in Rat Model via Increased Levels of Complex TF/VII, PAI-1, Platelet Activation as Well as Decreased Contents of SIRT1 and SIRT3.
- Authors:
- Malgorzata Karbowska, Tomasz W. Kaminski, Beata Znorko, Tomasz Domaniewski, Tomasz Misztal, Tomasz Rusak, Anna Pryczynicz, Katarzyna Guzinska-Ustymowicz, Krystyna Pawlak, Dariusz Pawlak
- Academic press:
- Frontiers in Physiology (year: 2018, volume: 9, pages: 1623 wersja elektroniczna), Publisher: Frontiers Media SA
- Status:
- Published
- DOI:
- 10.3389/fphys.2018.01623 – link to the publication
Articles in post-conference publications (1)
-
PROTHROMBOTIC PROPERTIES OF INDOXYL SULFATE IN ANIMAL MODEL OF ARTERIAL THROMBOSIS.
- Authors:
- Małgorzata Karbowska, Tomasz Kamiński, Dariusz Pawlak
- Conference:
- 3RD Lublin International Medical Congress for Students and Young Doctors Lublin (year: 2016, pages: 131), Publisher: Studenckie Koło Naukowe UM Lublin
- Date:
- conference 2 - 3.12.2016
- Status:
- Published