Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Effect of indoxyl sulfate on modulating the activity of hemostasis and hemodynamic parameters in animal model of experimental arterial thrombosis.

2015/17/N/NZ4/02334

Keywords:

indoxyl sulfate hemostasis intravital microscopy arterial thrombosis chronic kidney disease

Descriptors:

  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

woj. podlaskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Tomasz Kamiński 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2016-03-16

Project end date (Y-m-d): 2019-03-15

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. The uremic toxin indoxyl sulfate accelerates thrombotic response after vascular injury in animal models.
    Authors:
    Małgorzata Karbowska, Tomasz Kamiński, Natalia Marcińczyk, Tomasz Misztal, Tomasz Rusak, Łukasz Smyk, Dariusz Pawlak.
    Academic press:
    Toxins (rok: 2017, tom: 9, strony: 229 wersja elektroniczna), Wydawca: MDPI Switzerland
    Status:
    Published
    DOI:
    10.3390/toxins9070229 - link to the publication
  2. Indoxyl Sulfate Promotes Arterial Thrombosis in Rat Model via Increased Levels of Complex TF/VII, PAI-1, Platelet Activation as Well as Decreased Contents of SIRT1 and SIRT3.
    Authors:
    Malgorzata Karbowska, Tomasz W. Kaminski, Beata Znorko, Tomasz Domaniewski, Tomasz Misztal, Tomasz Rusak, Anna Pryczynicz, Katarzyna Guzinska-Ustymowicz, Krystyna Pawlak, Dariusz Pawlak
    Academic press:
    Frontiers in Physiology (rok: 2018, tom: 9, strony: 1623 wersja elektroniczna), Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fphys.2018.01623 - link to the publication
  1. PROTHROMBOTIC PROPERTIES OF INDOXYL SULFATE IN ANIMAL MODEL OF ARTERIAL THROMBOSIS.
    Authors:
    Małgorzata Karbowska, Tomasz Kamiński, Dariusz Pawlak
    Conference:
    3RD Lublin International Medical Congress for Students and Young Doctors Lublin (rok: 2016, ), Wydawca: Studenckie Koło Naukowe UM Lublin
    Data:
    konferencja 2 - 3.12.2016
    Status:
    Published

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