The role of Zebrafish mTOR in neuronal development in vivo as a key regulator of neuronal circuit formation.
2015/17/D/NZ3/03735
Keywords
Descriptors
- NZ3_6: Neurobiologia komórkowa
- NZ3_13: Biologia rozwoju zwierząt
- NZ3_5: Neurobiologia molekularna
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Międzynarodowy Instytut Biologii Molekularnej i Komórkowej
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
SONATA 9 – announced on 2015-03-16
- Amount awarded
- 689 000 PLN
- Project start date
- 2016-02-22
- Project end date
- 2019-12-21
- Project duration
- 46 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- DYSK ZEWNĘTRZNY. Cost: 307 PLN
- Oprogramowanie do analizy obrazów 3D. Cost: 12 000 PLN
- System do hodowli i utrzymania ryb. Cost: 50 000 PLN
Information in the final report
Publication in academic press/journals (5)
-
Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2.
- Authors:
- Alicja Koscielny, Anna R. Malik, Ewa Liszewska, Justyna Zmorzynska, Aleksandra Tempes, Bartosz Tarkowski, Jacek Jaworski
- Academic press:
- Molecular Neurobiology (year: 2018, volume: 55(2), pages: 1590-1606), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s12035-017-0436-3 – link to the publication
-
TrkB hyperactivity contributes to brain dysconnectivity, epileptogenesis, and anxiety in zebrafish model of Tuberous Sclerosis Complex
- Authors:
- Magdalena Kedra, Katarzyna Banasiak, Katarzyna Kisielewska, Lidia Wolinska-Niziol, Jacek Jaworski, and Justyna Zmorzynska
- Academic press:
- Proceedings of the National Academy of Sciences of the United States of America (PNAS) (year: 2020, volume: 117 (4), pages: 2170-2179), Publisher: PNAS
- Status:
- Published
- DOI:
- 10.1073/pnas.1910834117 – link to the publication
-
Molecular neurobiology of mTOR
- Authors:
- K. Switon, K. Kotulska, A. Janusz-Kaminska, J. Zmorzynska, J. Jaworski
- Academic press:
- Neuroscience (year: 2017, volume: 341, pages: 112-153), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.neuroscience.2016.11.017 – link to the publication
-
Tuberous Sclerosis Complex: From Molecular Biology to Novel Therapeutic Approaches.
- Authors:
- K. Switon, K. Kotulska, A. Janusz-Kaminska, J. Zmorzynska, J. Jaworski.
- Academic press:
- IUBMB Life (year: 2016, volume: 68(12), pages: 955-962), Publisher: John Wiley and sons, Inc.
- Status:
- Published
- DOI:
- 10.1002/iub.1579 – link to the publication
-
Okiem ryby - nowe spojrzenie na rozwój sieci neuronalnych i choroby neurorozwojowe.
- Authors:
- M. Kędra, J. Jaworski i J. Zmorzyńska.
- Academic press:
- Wszechświat Pismo Przyrodnicze (year: 2016, volume: 117(nr 10-12), pages: 270-277), Publisher: Polskie Towarzystwo Przyrodników im. Kopernika
- Status:
- Published