Bioconjugates of multimodal nanoparticles for targeted alpha and hyperthermia therapy. Synthesis, retention studies of recoiling daughter radionuclides and preliminary cell studies.

2015/17/N/ST4/03943

Keywords

Descriptors

  • ST4_16: Chemia jądrowa i radiacyjna
  • ST4_2: Nanochemia

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Instytut Chemii i Techniki Jądrowej

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Edyta Cędrowska

Number of co-investigators in the project: 2

Call

PRELUDIUM 9 – announced on 2015-03-16

Amount awarded
98 800 PLN
Project start date
2016-02-22
Project end date
2018-08-21
Project duration
30 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Urządzenie do jednoczestnego ogrzewania i mieszania próbek. Cost: 10 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Functionalized TiO2 nanoparticles labelled with 225Ac for targeted alpha radionuclide therapy

    Authors:
    Edyta CędrowskaMarek PruszynskiAgnieszka Majkowska-PilipSylwia Męczyńska-WielgoszFrank BruchertseiferAlfred MorgensternAleksander BilewiczEmail author
    Academic press:
    Journal of Nanoparticle Research (year: 2018, volume: 20, pages: 83 (1-10)), Publisher: Springer Netherlands
    Status:
    Published
    DOI:
    10.1007/s11051-018-4181-y – link to the publication
  2. Trastuzumab modified barium ferrite magnetic nanoparticles labeled with 223Ra: a new potential radiobioconjugate for alpha radioimmunotherapy and magnetic hyperthermia

    Authors:
    Weronika Gawęda, Marek Pruszynski, Edyta Cędrowska, Magdalena Rodak, Agnieszka Majkowska-Pilip, Damian Gawel, Frank Bruchertseifer, Alfred Morgenstern, Aleksander Bilewicz
    Academic press:
    Nanomaterials (year: 2020, volume: 10, pages: 2067), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10102067 – link to the publication

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Graphic design and implementation: Jakub Piotrowski