Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Thermosensitive star polymer surfaces for culturing and transfection of cells

2015/17/B/ST5/01095

Keywords:

star polymers polymer surfaces thermosensitivity gene therapy

Descriptors:

  • ST5_12: Methods of nanomaterials/materials synthesis
  • ST5_21:
  • ST5_3: Surface modification

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Materiałów Polimerowych i Węglowych PAN

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Kowalczuk 

Number of co-investigators in the project: 6

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 899 640 PLN

Project start date (Y-m-d): 2016-01-28

Project end date (Y-m-d): 2020-01-27

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikrowaga kwarcowa (372 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. Stable star polymer nanolayers and their thermoresponsiveness as a tool for controlled culture and detachment of fibroblast sheets
    Authors:
    Barbara Mendrek, Iwona-Żymełka-Miara, Łukasz Sieroń, Agnieszka Fus, Katarzyna Balin, Jerzy Kubacki, Mario Smet, Barbara Trzebicka, Aleksander L. Sieroń, Agnieszka Kowalczuk
    Academic press:
    Journal of Materials Chemistry B (rok: 2018, tom: 6, strony: 641-655), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C7TB02748F - link to the publication
  2. Star polymer-based nanolayers with immobilized complexes of polycationic stars and DNA for deposition gene delivery and recovery of intact transfected cells
    Authors:
    Barbara Mendrek, Agnieszka Fus-Kujawa, Paulina Teper, Malwina Botor, Jerzy Kubacki, Aleksander L. Sieroń, Agnieszka Kowalczuk
    Academic press:
    International Journal of Pharmaceutics (rok: 2020, tom: 589, strony: 119823-119839), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijpharm.2020.119823 - link to the publication
  3. Synthesis, characterization and cytotoxicity of novel thermoresponsive star copolymers of N,N'-dimethylaminoethyl methacrylate and hydroxyl-bearing oligo(ethylene glycol) methacrylate
    Authors:
    Barbara Mendrek, Agnieszka Fus, Katarzyna Klarzyńska, Aleksander L. Sieroń, Mario Smet, Agnieszka Kowalczuk, Andrzej Dworak
    Academic press:
    Polymers (rok: 2018, tom: 10 (11), strony: 1255), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym10111255 - link to the publication
  4. Functional star polymers as reagents for efficient nucleic acids delivery into HT-1080 cells
    Authors:
    Agnieszka Fus-Kujawa, Paulina Teper, Malwina Botor, Katarzyna Klarzyńska, Łukasz Sieroń, Bram Verbelen, Mario Smet, Aleksander L. Sieroń, Barbara Mendrek, Agnieszka Kowalczuk
    Academic press:
    International Journal of Polymeric Materials and Polymeric Biomaterials (rok: 2021, tom: 70(5), strony: 356-370), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/00914037.2020.1716227 - link to the publication
  1. The cytotoxicity studies of polycationic polymers with star topology in polyplexes with nucleic acids
    Authors:
    Malwina Botor, Agnieszka Fus, Agnieszka Kowalczuk, Barbara Mendrek, Aleksander L. Sieroń
    Conference:
    The 44th FEBS Congress (Federation of European Biochemical Societies), FEBS OPEN BIO (rok: 2019, ), Wydawca: The 44th FEBS Congress (Federation of European Biochemical Societies)
    Data:
    konferencja 6-11 czerwca 2019
    Status:
    Published

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