Thermosensitive star polymer surfaces for culturing and transfection of cells

2015/17/B/ST5/01095

Keywords

Descriptors

  • ST5_12: Materiały "inteligentne" – materiały samoorganizujące się, materiały reagujące na bodźce zewnętrzne
  • ST5_21: Chemia polimerów
  • ST5_3: Modyfikacja powierzchni materiałów

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Centrum Materiałów Polimerowych i Węglowych PAN

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Agnieszka Kowalczuk

Number of co-investigators in the project: 6

Call

OPUS 9 – announced on 2015-03-16

Amount awarded
899 640 PLN
Project start date
2016-01-28
Project end date
2020-01-27
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikrowaga kwarcowa. Cost: 372 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. Synthesis, characterization and cytotoxicity of novel thermoresponsive star copolymers of N,N'-dimethylaminoethyl methacrylate and hydroxyl-bearing oligo(ethylene glycol) methacrylate

    Authors:
    Barbara Mendrek, Agnieszka Fus, Katarzyna Klarzyńska, Aleksander L. Sieroń, Mario Smet, Agnieszka Kowalczuk, Andrzej Dworak
    Academic press:
    Polymers (year: 2018, volume: 10 (11), pages: 1255), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/polym10111255 – link to the publication
  2. Stable star polymer nanolayers and their thermoresponsiveness as a tool for controlled culture and detachment of fibroblast sheets

    Authors:
    Barbara Mendrek, Iwona-Żymełka-Miara, Łukasz Sieroń, Agnieszka Fus, Katarzyna Balin, Jerzy Kubacki, Mario Smet, Barbara Trzebicka, Aleksander L. Sieroń, Agnieszka Kowalczuk
    Academic press:
    Journal of Materials Chemistry B (year: 2018, volume: 6, pages: 641-655), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C7TB02748F – link to the publication
  3. Star polymer-based nanolayers with immobilized complexes of polycationic stars and DNA for deposition gene delivery and recovery of intact transfected cells

    Authors:
    Barbara Mendrek, Agnieszka Fus-Kujawa, Paulina Teper, Malwina Botor, Jerzy Kubacki, Aleksander L. Sieroń, Agnieszka Kowalczuk
    Academic press:
    International Journal of Pharmaceutics (year: 2020, volume: 589, pages: 119823-119839), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijpharm.2020.119823 – link to the publication
  4. Functional star polymers as reagents for efficient nucleic acids delivery into HT-1080 cells

    Authors:
    Agnieszka Fus-Kujawa, Paulina Teper, Malwina Botor, Katarzyna Klarzyńska, Łukasz Sieroń, Bram Verbelen, Mario Smet, Aleksander L. Sieroń, Barbara Mendrek, Agnieszka Kowalczuk
    Academic press:
    International Journal of Polymeric Materials and Polymeric Biomaterials (year: 2021, volume: 70(5), pages: 356-370), Publisher: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/00914037.2020.1716227 – link to the publication

Articles in post-conference publications (1)

  1. The cytotoxicity studies of polycationic polymers with star topology in polyplexes with nucleic acids

    Authors:
    Malwina Botor, Agnieszka Fus, Agnieszka Kowalczuk, Barbara Mendrek, Aleksander L. Sieroń
    Conference:
    The 44th FEBS Congress (Federation of European Biochemical Societies), FEBS OPEN BIO (year: 2019, pages: Volume: 9, Pages: 214-214), Publisher: The 44th FEBS Congress (Federation of European Biochemical Societies)
    Date:
    conference 6-11 czerwca 2019
    Status:
    Published

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