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Information on the principal investigator and host institution

Information of the project and the call

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Wpływ inhibitorów deacetylaz histonów na regulację cząsteczki CD20 w komórkach nowotworowych

2015/16/T/NZ6/00034

Keywords:

Descriptors:

  • NZ3_1: Cell biology
  • NZ5_7: Human disease treatment
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Małgorzata Bobrowicz 

Number of co-investigators in the project: 2

Call: ETIUDA 3 - announced on 2014-12-15

Amount awarded: 54 596 PLN

Project start date (Y-m-d): 2015-10-01

Project end date (Y-m-d): 2016-06-30

Project duration:: 9 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. FOXO1 alters efficacy of rituximab-based therapy by suppressing MS4A1/CD20 expression
    Authors:
    Beata Pyrzynska, Michal Dwojak, Abdessamad Zerrouqi, Giulia Morlino, Piotr Zapala, Nina Miazek, Agnieszka Zagozdzon, Kamil Bojarczuk, Malgorzata Bobrowicz, Marta Siernicka, Marcin M. Machnicki, Joanna Barankiewicz, Ewa Lech-Maranda, Przemyslaw Juszczynski, Dinis Calado, Jakub Golab, Magdalena Winiarska
    Academic press:
    Oncoimmunology (rok: 2018, tom: 7, strony: e1423183-1 - e1423183-9), Wydawca: Francis & Taylor Group
    Status:
    Published
    DOI:
    10.1080/2162402X.2017.1423183 - link to the publication
  2. HDAC6 inhibition up-regulates CD20 level and increases the efficacy of anti-CD20 monoclonal antibodies.
    Authors:
    Malgorzata Bobrowicz, Michal Dwojak, Beata Pyrzynska, Elise Berthel, Nicole Dalla Venezia, Mieszko Kozikowski, Joanna Stachura, Agata Malenda, Marta Siernicka, Antoni Domagala, Kamil Bojarczuk, Agnieszka Zagozdzon, Magdalena Gabrysiak, Nina Miazek, Piotr Zapala, Jean-Jacques Diaz, Marta Karp, Ewa Lech-Maranda, Malgorzata Firczuk, Abdessamad Zerrouqi, Krzysztof Giannopoulos, Jakub Golab, and Magdalena Winiarska
    Academic press:
    Blood (rok: 2018, tom: 130, strony: 1628-1638), Wydawca: American Society of Hematology
    Status:
    Published
    DOI:
    10.1182/blood-2016-08-736066 - link to the publication
  1. HDAC6 INHIBITION SENSITIZES TUMOR CELLS TO ANTI-CD20 IMMUNOTHERAPY IN VIVO
    Authors:
    Malgorzata Bobrowicz , Michal Dwojak , Joanna Stachura , Muchowicz Angelika , Pyrzynska Beata , Siernicka Marta , Nina Miazek , Piotr Zapala , Jakub Golab , Magdalena Winiarska
    Conference:
    22nd Congress Of The European Hematology Association (rok: 2017, ), Wydawca: European Hematology Association
    Data:
    konferencja 22-25.06.
    Status:
    Published
  2. Wpływ inhibitorów deacetylaz histonów na regulację cząsteczki CD20 w komórkach nowotworowych
    Authors:
    Małgorzata Bobrowicz
    Conference:
    XII Konferencja Naukowa I Wydziału Lekarskiego pt. "Postępy onkologii eksperymentalnej i klinicznej". (rok: 2017, ), Wydawca: Warszawski Uniwersytet Medyczny
    Data:
    konferencja 23-05-2017
    Status:
    Published
  3. HDAC6 INHIBITION INCREASES CD20 LEVEL BY STIMULATING TRANSLATION OF CD20 MRNA
    Authors:
    A. Graczyk-Jarzynka,, M. Bobrowicz, M. Dwojak, J. Stachura, E. Berthel, B. Pyrzyńska, M. Siernicka, N. Miązek, P. Zapała, N. Dalla-Venezia, J. Gołąb, M. Winiarska
    Conference:
    22nd Congress Of The European Hematology Association (rok: 2017, ), Wydawca: European Hematology Association
    Data:
    konferencja 22-25.06.
    Status:
    Published