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Wpływ inhibitorów deacetylaz histonów na regulację cząsteczki CD20 w komórkach nowotworowych

2015/16/T/NZ6/00034

Descriptors

  • NZ3_1: Biologia komórki
  • NZ5_7: Leczenie chorób człowieka
  • NZ6_1: Odporność swoista i nieswoista

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Małgorzata Bobrowicz

Number of co-investigators in the project: 2

Call

ETIUDA 3 – announced on 2014-12-15

Amount awarded
54 596 PLN
Project start date
2015-10-01
Project end date
2016-06-30
Project duration
9 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (2)

  1. FOXO1 alters efficacy of rituximab-based therapy by suppressing MS4A1/CD20 expression

    Authors:
    Beata Pyrzynska, Michal Dwojak, Abdessamad Zerrouqi, Giulia Morlino, Piotr Zapala, Nina Miazek, Agnieszka Zagozdzon, Kamil Bojarczuk, Malgorzata Bobrowicz, Marta Siernicka, Marcin M. Machnicki, Joanna Barankiewicz, Ewa Lech-Maranda, Przemyslaw Juszczynski, Dinis Calado, Jakub Golab, Magdalena Winiarska
    Academic press:
    Oncoimmunology (year: 2018, volume: 7, pages: e1423183-1 - e1423183-9), Publisher: Francis & Taylor Group
    Status:
    Published
    DOI:
    10.1080/2162402X.2017.1423183 – link to the publication

  2. HDAC6 inhibition up-regulates CD20 level and increases the efficacy of anti-CD20 monoclonal antibodies.

    Authors:
    Malgorzata Bobrowicz, Michal Dwojak, Beata Pyrzynska, Elise Berthel, Nicole Dalla Venezia, Mieszko Kozikowski, Joanna Stachura, Agata Malenda, Marta Siernicka, Antoni Domagala, Kamil Bojarczuk, Agnieszka Zagozdzon, Magdalena Gabrysiak, Nina Miazek, Piotr Zapala, Jean-Jacques Diaz, Marta Karp, Ewa Lech-Maranda, Malgorzata Firczuk, Abdessamad Zerrouqi, Krzysztof Giannopoulos, Jakub Golab, and Magdalena Winiarska
    Academic press:
    Blood (year: 2018, volume: 130, pages: 1628-1638), Publisher: American Society of Hematology
    Status:
    Published
    DOI:
    10.1182/blood-2016-08-736066 – link to the publication

Articles in post-conference publications (3)

  1. HDAC6 INHIBITION INCREASES CD20 LEVEL BY STIMULATING TRANSLATION OF CD20 MRNA

    Authors:
    A. Graczyk-Jarzynka,, M. Bobrowicz, M. Dwojak, J. Stachura, E. Berthel, B. Pyrzyńska, M. Siernicka, N. Miązek, P. Zapała, N. Dalla-Venezia, J. Gołąb, M. Winiarska
    Conference:
    22nd Congress Of The European Hematology Association (year: 2017, pages: 559), Publisher: European Hematology Association
    Date:
    conference 22-25.06.
    Status:
    Published
    DOI:
    link to the publication

  2. HDAC6 INHIBITION SENSITIZES TUMOR CELLS TO ANTI-CD20 IMMUNOTHERAPY IN VIVO

    Authors:
    Malgorzata Bobrowicz , Michal Dwojak , Joanna Stachura , Muchowicz Angelika , Pyrzynska Beata , Siernicka Marta , Nina Miazek , Piotr Zapala , Jakub Golab , Magdalena Winiarska
    Conference:
    22nd Congress Of The European Hematology Association (year: 2017, pages: 568), Publisher: European Hematology Association
    Date:
    conference 22-25.06.
    Status:
    Published
    DOI:
    link to the publication

  3. Wpływ inhibitorów deacetylaz histonów na regulację cząsteczki CD20 w komórkach nowotworowych

    Authors:
    Małgorzata Bobrowicz
    Conference:
    XII Konferencja Naukowa I Wydziału Lekarskiego pt. Postępy onkologii eksperymentalnej i klinicznej. (year: 2017, pages: 26-27), Publisher: Warszawski Uniwersytet Medyczny
    Date:
    conference 23-05-2017
    Status:
    Published
    DOI:
    link to the publication

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