Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Optimisation of biocompatible scaffolds combinig graphen and defined stem cell populations for tissue regeneration.

2015/16/W/NZ4/00071

Keywords:

graphen biocompatible scaffolds stem cells tissue regeneration

Descriptors:

  • NZ3_8: Stem cell biology
  • NZ5_7: Human disease treatment
  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ewa Zuba-Surma 

Number of co-investigators in the project: 9

Call: SYMFONIA 3 - announced on 2014-12-15

Amount awarded: 4 988 400 PLN

Project start date (Y-m-d): 2015-11-27

Project end date (Y-m-d): 2020-11-26

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. 384-dołkowy blok grzejny do termocyklera (100 000 PLN)
  2. Autoklaw (10 000 PLN)
  3. Komora laminarna (20 000 PLN)
  4. Automatyczna płuczka do mikropłytek (50 000 PLN)
  5. Mieszadło magnetyczne (10 000 PLN)
  6. Wieloparametrowy miernik laboratoryjny (10 000 PLN)
  7. Dygestorium (80 000 PLN)
  8. Płuczka ultradźwiękowa (10 000 PLN)
  9. Waga analityczna.
  10. Wagosuszarka (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (4)
  • Book publications / chapters in book publications (1)
  1. Graphene-based materials enhance cardiomyogenic and angiogenic differentiation capacity of human mesenchymal stem cells in vitro – Focus on cardiac tissue regeneration
    Authors:
    Sekuła-Stryjewska M, Noga S, Dwigońska M, Adamczyk E, Karnas E, Jagiełło J, Szkaradek A, Chytrosz P, Boruczkowski D, Madeja Z, Kotarba A, Lipińska L, Zuba-Surma E
    Academic press:
    Mater Sci Eng C (rok: 2021, tom: 119 (111614), strony: 45309), Wydawca: Elsevier ScienceDirect
    Status:
    Published
    DOI:
    10.1016/j.msec.2020.111614 - link to the publication
  2. Investigation into morphological and electromechanical surface properties of reduced-graphene-oxide-loaded composite fibers for bone tissue engineering applications: a comprehensive nanoscale study using atomic force microscopy approach
    Authors:
    A. Chlanda, E. Walejewska, K. Kowiorski, M. Heljak, W. Swieszkowski, L. Lipińska
    Academic press:
    Micron (rok: 2021, tom: 146, strony: 103072), Wydawca: Elsevier Science Direct
    Status:
    Published
    DOI:
    10.1016/j.micron.2021.103072 - link to the publication
  3. Perspectives for Future Use of Extracellular Vesicles from Umbilical Cord- and Adipose Tissue-Derived Mesenchymal Stem/Stromal Cells in Regenerative Therapies—Synthetic Review
    Authors:
    Lelek J, Zuba-Surma E
    Academic press:
    Int J Mol Sci (rok: 2020, tom: 21, strony: 799-818), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21030799 - link to the publication
  4. Impact of developmental origin, niche mechanics and oxygen availability on osteogenic differentiation capacity of mesenchymal stem/stromal cells.
    Authors:
    Bryniarska N, Kubiak A, Łabędź-Masłowska A, Zuba-Surma E
    Academic press:
    Acta Biochim Pol (rok: 2019, tom: 66 (4), strony: 491-498), Wydawca: PTBioch
    Status:
    Published
    DOI:
    10.18388/abp.2019_2893 - link to the publication
  5. Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles
    Authors:
    Bobis-Wozowicz S, Kmiotek K, Kania K, Karnas E, Labedz-Maslowska A, Sekula M, Kedracka-Krok S, Kolcz J, Boruczkowski D, Madeja Z, Zuba-Surma EK.
    Academic press:
    J Mol Med (Berl). (rok: 2017, tom: 95, strony: 205-220), Wydawca: Springer International Publishing AG. Part of Springer Nature.
    Status:
    Published
    DOI:
    10.1007/s00109-016-1471-7 - link to the publication
  6. Morphology and Chemical Purity ofWater Suspension of Graphene Oxide FLAKES Aged for 14 Months in Ambient Conditions. A Preliminary Study
    Authors:
    A. Chlanda, K. Kowiorski, M. Małek, E. Kijeńska-Gawrońska, M. Bil, M. Djas, T. Stachowski, W. Swieszkowski, L. Lipińska
    Academic press:
    Materials (rok: 2021, tom: 14 (15), strony: 4108), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14154108 - link to the publication
  7. Synthesis and Characterization of Graphene Oxide and Reduced Graphene Oxide Composites with Inorganic Nanoparticles for Biomedical Applications
    Authors:
    J. Jagiełło, A. Chlanda, M. Baran, M. Gwiazda, L. Lipińska
    Academic press:
    Nanomaterials (rok: 2020, tom: 10 (1846), strony: 45309), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10091846 - link to the publication
  8. Impact of Graphene-Based Surfaces on the Basic Biological Properties of Human Umbilical Cord Mesenchymal Stem Cells: Implications for Ex Vivo Cell Expansion Aimed at Tissue Repair
    Authors:
    Jagiełło J, Sekuła-Stryjewska M, Noga S, Adamczyk E, Dźwigońska M, Kurcz M, Kurp K, Winkowska-Struzik M, Karnas E, Boruczkowski D, Madeja Z, Lipińska L, Zuba-Surma EK
    Academic press:
    Int. J. Mol. Sci. (rok: 2019, tom: 20 (18), strony: 4561), Wydawca: MDPI AG
    Status:
    Published
    DOI:
    10.3390/ijms20184561 - link to the publication
  1. Graphene-based substrates influence biological and functional properties of human umbilical cord-derived mesenchymal stem cells
    Authors:
    Sekuła M., Karnas E., Jagiełło J., Noga S., Adamczyk E., Dźwigońska M., Kmiotek K., Baran M., Madeja Z., Lipińska L., Zuba-Surma E.
    Conference:
    25th Anniversary Conference on Biomaterials in Medicine and Veterinary Medicine (rok: 2016, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 13-16 October
    Status:
    Published
  2. Application of polymer- and graphene- based materials in biomedical research
    Authors:
    Sekuła M, Domalik-Pyzik P, Noga S, Karnas E, Kosowska K, Hunger M, Złocista-Szewczyk N, Jagiełło J, Lipińska L, Pielichowska K, Chłopek J, Zuba-Surma EK
    Conference:
    27th Anniversary Conference on Biomaterials in Medicine and Veterinary Medicine (rok: 2018, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 11-14 October
    Status:
    Published
  3. Mesenchymal stem cells and graphene-based substrates as novel grafts in cardiac tissue regeneration.
    Authors:
    M. Sekuła, J. Jagiełło, E. Karnas, S. Noga, M. Dźwigońska, E. Adamczyk, Z. Madeja, L. Lipińska, E.K. Zuba-Surma.
    Conference:
    42nd FEBS Congress (rok: 2017, ), Wydawca: FEBS PRESS (The FEBS Journal)
    Data:
    konferencja 10-14 September
    Status:
    Published
    DOI:
    link to the publication
  4. Utilization of graphene- based materials and mesenchymal stem cells in regenerative medicine.
    Authors:
    6)Sekuła-Stryjewska M, Noga S, Byrska A, Pabis M, Lelek J, Jagiełło J, Madeja Z, Lipińska L, Zuba-Surma EK.
    Conference:
    28th Anniversary Conference on Biomaterials in Medicine and Veterinary Medicine (rok: 2019, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 10-13 October
    Status:
    Published
  1. Biomaterials and Stem Cells: Promising Tools in Tissue Engineering and Biomedical Applications
    Authors:
    Sekula M., Zuba-Surma EK.
    Book:
    Biomaterials in Regenerative Medicine (rok: 2017, tom: 1, strony: 361-378), Wydawca: InTech - open science (http://www.intechopen.com)
    Status:
    Published
    DOI:
    link to the publication

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