Analiza ilościowa i jakościowa mechanizmów gromadzenia białka XRCC1 w rejonach endogennych, jednoniciowych pęknięć powstających w replikowanym DNA.
2015/16/T/NZ3/00157
Descriptors
- NZ3_1: Biologia komórki
- NZ3_4: Starzenie
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
ETIUDA 3 – announced on 2014-12-15
- Amount awarded
- 98 540 PLN
- Project start date
- 2015-10-01
- Project end date
- 2016-09-30
- Project duration
- 12 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (2)
-
Two stages of XRCC1 recruitment and two classes of XRCC1 foci formed in response to low level DNA damage induced by visible light, or stress triggered by heat shock
- Authors:
- Kamil J. Solarczyk, Magdalena Kordon, Krzysztof Berniak, Jurek W. Dobrucki
- Academic press:
- DNA Repair (year: 2016, volume: 37, pages: 46377), Publisher: ELSEVIER
- Status:
- Published
- DOI:
- 10.1016/j.dnarep.2015.10.006 – link to the publication
-
PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks.
- Authors:
- Magdalena M. Kordon, Aleksander Szczurek, Krzysztof Berniak, Oskar Szelest, Kamil Solarczyk, Magdalena Tworzydło, Sebastian Wachsmann-Hogiu, Anne Vaahtokari, Christoph Cremer, Thoru Pederson, Jurek W. Dobrucki
- Academic press:
- The FASEB Journal (year: 2019, volume: 33(2), pages: 2301-2313), Publisher: The Federation of American Societies for Experimental Biology
- Status:
- Published
- DOI:
- 10.1096/fj.201801379R – link to the publication