Composites of nucleic acids and oligofunctionalized boron clusters as new material for bionanotechnology
2015/16/W/ST5/00413
Keywords
Descriptors
- ST5_11: Synteza biomateriałów
- ST5_10: Nanomateriały: nanocząstki, nanorurki
- ST5_9: Materiały do konstrukcji sensorów
Panel
ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution
Instytut Biologii Medycznej PAN
Voivodeship: łódzkie
Principal investigator (from the host institution)
prof. Zbigniew Jan Leśnikowski
Number of co-investigators in the project: 9
Call
SYMFONIA 3 – announced on 2014-12-15
- Amount awarded
- 3 430 080 PLN
- Project start date
- 2015-11-16
- Project end date
- 2022-11-15
- Project duration
- 84 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Agregat chłodzący (2 pcs). Cost: 33 200 PLN
- DNA/RNA Syntetyzer. Cost: 180 000 PLN
- Liofilizator. Cost: 75 000 PLN
- Pompa hybrydowa. Cost: 25 000 PLN
- Reaktor mikrofalowy.
- Spektrofotometr przenośny w kropli. Cost: 39 800 PLN
- System do chromatografii kartridżowej. Cost: 270 000 PLN
- System wyparki obrotowej z wyposażeniem (2 pcs). Cost: 70 000 PLN
- Wirówka próżniowa typu "Speedvac". Cost: 55 000 PLN
- Wytrząsarka o ruchu koziołkującym, wielofuncyjna.. Cost: 32 000 PLN
Information in the final report
Publication in academic press/journals (17)
-
Boron Clusters as a Platform for New Materials: Composites of Nucleic Acids and Oligofunctionalized Carboranes (C2B10H12) and their Assembly into Functional Nanoparticles
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbinska, Katarzyna Kulik, Slawomir Janczak, Anna Maciaszek, Katarzyna Bednarska, Barbara Nawrot and Zbigniew Lesnikowski
- Academic press:
- Nanoscale (year: 2020, volume: 12, pages: 103-114), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/C9NR06550D – link to the publication
-
Recent developments with boron as a platform for novel drug design
- Authors:
- Zbigniew J. Leśnikowski
- Academic press:
- Expert Opinion on Drug Discovery (year: 2016, volume: 11, pages: 569–578), Publisher: Taylor & Francis
- Status:
- Published
- DOI:
- 10.1080/17460441.2016.1174687 – link to the publication
-
Synthesis and in vitro evaluation of antiviral and cytostatic properties of novel 8-triazolyl acyclovir derivatives
- Authors:
- Dijana Saftić, Biserka Žinić, Ljubica Glavaš-Obrovac, Mirosława Studzińska, Edyta Paradowska & Zbigniew J. Leśnikowski
- Academic press:
- Nucleosides, Nucleotides and Nucleic Acids (year: 2018, volume: 37, pages: 397-414), Publisher: Taylor & Francis
- Status:
- Published
- DOI:
- 10.1080/15257770.2018.1485932 – link to the publication
-
Insights into molecular structure of adenosine-boron cluster conjugates and theirs phenyl isosters as adenosine receptor ligands: Nuclear magnetic resonance, crystallographic and computational studies
- Authors:
- Daniel Baranowski, Adam Mieczkowski, Damian Trzybiński, Krzysztof Woźniak, Katarzyna Bednarska-Szczepaniak, Zofia Gdaniec, Zbigniew J. Leśnikowski
- Academic press:
- Journal of Molecular Structure (year: 2023, volume: 1274, pages: 134588), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.molstruc.2022.134588 – link to the publication
-
EGFR-targeted cellular delivery of therapeutic nucleic acids mediated by boron clusters
- Authors:
- Kaniowski D., Suwara J., Ebenryter-Olbińska K., Jakóbik-Kolon A., Nawrot B.
- Academic press:
- International Journal of Molecular Sciences (year: 2022, volume: 23, pages: 14793), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms232314793 – link to the publication
-
High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbinska, Milena Sobczak, BłazejWojtczak, Sławomir Janczak, Zbigniew J. Lesnikowski, Barbara Nawrot
- Academic press:
- Molecules (year: 2017, volume: 22, pages: 46042), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/molecules22091393 – link to the publication
-
Versatile Method for the Site-Specific Modification of DNA with Boron Clusters: Anti-Epidermal Growth Factor Receptor (EGFR) Antisense Oligonucleotide Case
- Authors:
- Katarzyna Ebenryter-Olbinska, Damian Kaniowski, Milena Sobczak, Błazej A. Wojtczak, Sławomir Janczak, Ewelina Wielgus, Barbara Nawrot, Zbigniew J. Lesnikowski
- Academic press:
- Chemistry A European Journal (year: 2017, volume: 23, pages: 16535 – 16546), Publisher: Wiley
- Status:
- Published
- DOI:
- 10.1002/chem.201702957 – link to the publication
-
Boron clusters as enhancers of RNase H activity in the smart strategy of gene silencing by antisense oligonucleotides
- Authors:
- Kaniowski D., Kulik K., Suwara J., Ebenryter-Olbińska K., Nawrot B.
- Academic press:
- International Journal of Molecular Sciences (year: 2022, volume: 23, pages: 12190), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms232012190 – link to the publication
-
Unusual resistance of cobalt bis dicarbollide phosphate and phosphorothioate bridged esters towards alkaline hydrolysis: The metallacarborane effect
- Authors:
- Carla Sardo, Sławomir Janczak and Zbigniew J. Leśniowski
- Academic press:
- Journal of Organometallic Chemistry (year: 2019, volume: 896, pages: 70-76), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jorganchem.2019.06.001 – link to the publication
-
DNA Modified with Boron–Metal Cluster Complexes [M(C2B9H11)2]—Synthesis, Properties, and Applications
- Authors:
- Agnieszka B. Olejniczak, Barbara Nawrot and Zbigniew J. Lesnikowski
- Academic press:
- International Journal of Molecular Sciences (year: 2018, volume: 19, pages: 46035), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms19113501 – link to the publication
-
Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing
- Authors:
- David Kodr, Cansu Pinar Yenice, Anna Simonova, Dijana Pavlović-Saftic, Radek Pohl, ́Veronika Sykorová, Mayreli Ortiz, Ludek Havran, Miroslav Fojta, Zbigniew J. Lesnikowski, Ciara K. O'Sullivan, Michal Hocek
- Academic press:
- Journal of American Chemical Society (year: 2021, volume: 143, pages: 7124-7134), Publisher: American Chemical Society
- Status:
- Published
- DOI:
- 10.1021/jacs.1c02222 – link to the publication
-
Antiviral Effect of Nonfunctionalized Gold Nanoparticles against Herpes Simplex Virus Type-1 (HSV-1) and Possible Contribution of Near-Field Interaction Mechanism
- Authors:
- Edyta Paradowska, Mirosława Studzinska, Agnieszka Jabłonska, Valeri Lozovski, Natalia Rusinchuk, Iuliia Mukha, Nadiia Vitiuk, Zbigniew J. Lesnikowski
- Academic press:
- Molecules (year: 2021, volume: 26, pages: 5960), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/molecules26195960 – link to the publication
-
Comparative study of the effects of ortho-, meta- and para-carboranes (C2B10H12) on the physicochemical properties, cytotoxicity and antiviral activity of uridine and 2'-deoxyuridine boron cluster conjugate
- Authors:
- Dijana Saftić, Mirosława Studzińska, Edyta Paradowska, Ivo Piantanida, Goran Baranović, Magdalena Białek-Pietras and Zbigniew J. Leśnikowski
- Academic press:
- Bioorganic Chemistry (year: 2020, volume: 94, pages: 103466), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.bioorg.2019.103466 – link to the publication
-
Intramolecular rotations and electronic states of iron in the iron bis(dicarbollide) complex Fe[(C2B9H11)2] studied by a 57Fe nuclear probe and computational methods.
- Authors:
- Katarzyna Bednarska-Szczepaniak, Katarzyna Dziedzic-Kocurek, Ewelina Przelazły, Jan Stanek and Zbigniew J. Leśnikowski
- Academic press:
- Chemical Communications (year: 2022, volume: 58, pages: 391-394), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/D1CC05111C – link to the publication
-
What are the current challenges with the application of boron clusters to drug design?
- Authors:
- Zbigniew J. Leśnikowski
- Academic press:
- Expert Opinion on Drug Discovery (year: 2020, volume: 15, pages: 46025), Publisher: Taylor & Francis
- Status:
- Published
- DOI:
- 10.1080/17460441.2021.1867531 – link to the publication
-
Composites of Nucleic Acids and Boron Clusters (C2B10H12) as Functional Nanoparticles for Downregulation of EGFR Oncogene in Cancer Cells
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbinska, Katarzyna Kulik, Justyna Suwara, Wojciech Cypryk, Agata Jakóbik-Kolon, Zbigniew Lesnikowski, Barbara Nawrot
- Academic press:
- International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 4863), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms22094863 – link to the publication
-
Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase
- Authors:
- Damian Kaniowski, Katarzyna Kulik, Katarzyna Ebenryter-Olbińska, Ewelina Wielgus, Zbigniew Leśnikowski and Barbara Nawrot
- Academic press:
- Biomolecules (year: 2020, volume: 10, pages: 46042), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/biom10050718 – link to the publication
Articles in post-conference publications (37)
-
Comparative study of inorganic (boron cluster) and organic (phenyl) adenosine modifications as adenosine receptors ligands: Synthesis, in silico docking and physicochemical and biological evaluation
- Authors:
- Aleksandra Kierozalska, Adam Mieczkowski, Dijana Saftić, Katarzyna Bednarska, Tomasz Przygodzki, Kamil Karolczak, Cezary Watała, Magdalena Białek-Pietras, Tomasz M. Goszczyński, Mirosława Studzińska, Edyta Paradowska, Harsha Rao, Zhan-Guo Gao, Kenneth A. Jacobson and Zbigniew J. Leśnikowski
- Conference:
- 8th European Conference on Boron Chemistry (EUROBORON 8) (year: 2019, pages: 50), Publisher: Universite de Montpellier
- Date:
- conference 24-28 June 2019, Montpellier
- Status:
- Published
-
Klastery boru skoniugowane z kwasami nukleinowymi – nowy materiał dla bionanotechnologii
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Katarzyna Kulik, Anna Maciaszek, Zbigniew J. Leśnikowski, Barbara Nawrot
- Conference:
- STM/AFM NANOSAM (year: 2018, pages: P-I-7), Publisher: Uniwersytet Jagielloński
- Date:
- conference 28 listopada - 2 grudnia
- Status:
- Published
-
Functionalization of metallacarboranes – Synthesis of cobalt bis dicarbollide cyclic phosphorothioate ester and its alkylation
- Authors:
- Carla Sardo, Róża Hamera-Fałdyga, Krzysztof Śmiałkowski, Zbigniew Leśnikowski
- Conference:
- XXII International Symposium Advances in the Chemistry of Heteroorganic Compounds (year: 2019, pages: P-105), Publisher: CBMiM PAN, PTCh
- Date:
- conference 22 listopada
- Status:
- Published
-
Synthesis and physico-chemical and biological properties of oligopods of boron clusters and antisense oligonucleotides
- Authors:
- Kaniowski, K. Ebenryter-Olbińska, K. Kulik, M. Sobczak, S. Janczak, Z. J. Leśnikowski and B. Nawrot
- Conference:
- XI Ogólnopolskie Sympozjum Chemii Heteroorganicznej (year: 2018, pages: P-24), Publisher: OSCO
- Date:
- conference 8-11 kwietnia
- Status:
- Published
-
Composites of nucleic acids with oligofunctionalized carboranes as functional nanoparticles about two faces: anti-EGFR in cancer cells and carriers of boron for BNCT
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Katarzyna Kulik, Anna Maciaszek, Wojciech Cypryk, Agata Jakóbik-Kolon, Zbigniew J. Leśnikowski, Barbara Nawrot
- Conference:
- 63 Zjazd Polskiego Towarzystwa Chemicznego (year: 2021, pages: S02 P019), Publisher: 63 PTCH
- Date:
- conference 2021-09-13-17
- Status:
- Published
-
Composites of nucleic acids with oligofunctionalized carboranes (C2B10H12) as functional nanoparticles for downregulation of EGFR in cancer cells and carriers of boron for BNCT
- Authors:
- D. Kaniowski, K. Ebenryter-Olbińska, K. Kulik, A. Maciaszek, Agata Jakóbik-Kolon, Z.J. Leśnikowski and B. Nawrot
- Conference:
- Cold Spring Harbour Laboratory (year: 2021, pages: 44), Publisher: Cold Spring Harbour Laboratory
- Date:
- conference 2021-03-24-26
- Status:
- Published
-
Nanostructures of conjugates of antisense oligonucleotides and boron clusters as potential dual-action therapeutic nucleic acids
- Authors:
- . D.Kaniowski, K.Ebenryter-Olbińska, K.Kulik, A.Maciaszek, Z.J. Leśnikowski and B.Nawrot
- Conference:
- IFF Spring School Forschugszentrum (year: 2019, pages: 30), Publisher: Forschungszentrum Jülich
- Date:
- conference 11-22 marca
- Status:
- Published
-
Conjugates of antisense oligonucleotides with boron clusters: new material for boron neutron capture therapy (BNCT)
- Authors:
- D.Kaniowski, K.Ebenryter-Olbińska, K.Kulik, A.Maciaszek, Z.J. Leśnikowski, B.Nawrot
- Conference:
- 8th Intercollegiate Biotechnology Symposium 'Symbioza', Warsaw (year: 2019, pages: P15), Publisher: Politechnika Warszawska
- Date:
- conference 17-19 maj
- Status:
- Published
-
Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase
- Authors:
- Katarzyna Ebenryter-Olbińska, Damian Kaniowski, Katarzyna Kulik, Ewelina Wielgus, Zbigniew Leśnikowski, Barbara Nawrot
- Conference:
- 63 Zjazd Polskiego Towarzystwa Chemicznego (year: 2021, pages: S02 P021), Publisher: 63 PTCH
- Date:
- conference 2021-09-13-17
- Status:
- Published
-
New conjugates of DNA-boron clusters with two faces
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Katarzyna Kulik, Anna Maciaszek, Justyna Suwara, Wojciech Cypryk, Agata Jakóbik-Kolon, Zbigniew J. Leśnikowski and Barbara Nawrot
- Conference:
- IS3NA-IRT Virtual Virtual Symposium Symposium (year: 2021, pages: PL12), Publisher: International Society of Nucleosides, Nucleotides and Nucleic Acids
- Date:
- conference 2021-08-26-27
- Status:
- Published
-
Anti-EGFR silencing activity of antisense oligonucleotides labeled with boron clusters
- Authors:
- D. Kaniowski, K. Ebenryter-Olbińska, ZJ. Leśnikowski, B. Nawrot
- Conference:
- XVIIth Symposium on Chemistry of Nucleic Acid Components (year: 2017, pages: 154), Publisher: UOCHB AV CR
- Date:
- conference June 4-9
- Status:
- Published
-
Anti-EGFR antisense oligonucleotides conjugated with metallacarboranyl clusters
- Authors:
- D. Kaniowski, K. Ebenryter-Olbińska, ZJ. Leśnikowski, B. Nawrot
- Conference:
- 60 Zjazd PTCh (year: 2017, pages: 604), Publisher: PTCh
- Date:
- conference 17-21 września
- Status:
- Published
-
Aromaticity in 3D -Putting boron clusters at work
- Authors:
- C. Sardo, S. Janczak, ZJ. Leśnikowski
- Conference:
- XX International Symposium Advances in the Chemistry of Heteroorganic Compounds (year: 2017, pages: P-033), Publisher: CBMiM PAN
- Date:
- conference November 23-24
- Status:
- Published
-
Synthesis, anticancer and antiviral activity of novel 8-(4-substituted-1H-1,2,3-triazol-1-yl)purine derivatives
- Authors:
- D. Saftic, L. Glavas-Obrovac, M. Studzińska, E. Paradowska, ZJ. Leśnikowski, B. Zinic
- Conference:
- VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (year: 2017, pages: P351), Publisher: EFMC
- Date:
- conference August 27-31
- Status:
- Published
-
Nietypowa odporność na hydrolizę alkaliczną estrów p-nitrofenylowych cyklicznych tiofosforanów bishydroksymetalokarboranów
- Authors:
- S. Janczak, Z.J. Leśnikowski
- Conference:
- 59 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2016, pages: 132 S03P09), Publisher: Uniwersytet im. Adama Mickiewicza
- Date:
- conference 19-23 września
- Status:
- Published
-
Development of a dual fluorescence assay for monitoring of anti-EGFR silencing activity of chemically modified oligonucleotides; construction of pGFP-EGFR fusion plasmid
- Authors:
- D. Kaniowski, B. Nawrot
- Conference:
- 59 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2016, pages: 89 S01P35), Publisher: Uniwersytet im. Adama Mickiewicza
- Date:
- conference 19-23 września
- Status:
- Published
-
Boron clusters oligopods: New tool for nanoconstruction
- Authors:
- Carla Sardo and Zbigniew J. Leśnikowski
- Conference:
- NanoTech Poland 2017 (year: 2017, pages: 183), Publisher: Uniwersytet im. Adama Mickiewicza, Poznań
- Date:
- conference 1st–3rd JUNE
- Status:
- Published
-
Synthesis, physicochemical and biological properties of DNA oligonucleotides modified with boron clusters
- Authors:
- Katarzyna Ebenryter-Olbińska, Damian Kaniowski, Zbigniew Leśnikowski, Barbara Nawrot
- Conference:
- XIX International Symposium Advances in the Chemistry of Heteroorganic Compounds (year: 2016, pages: P059), Publisher: Polskie Towarzystwo Chemiczne
- Date:
- conference 25 listopada
- Status:
- Published
-
Synthesis and physicochemical modification of antisense oligonucleotides modified with boron clusters
- Authors:
- K. Ebenryter-Olbińska, M. Sobczak, D. Kaniowski, ZJ. Leśnikowski, B. Nawrot
- Conference:
- XVIIth Symposium on Chemistry of Nucleic Acid Components (year: 2017, pages: 133), Publisher: UOCHB AV CR
- Date:
- conference June 4-9
- Status:
- Published
-
BORON CLUSTERS – FROM NANOMACHINES TO DNA-NANOCONSTRUCTION
- Authors:
- Zbigniew J. Lesnikowski
- Conference:
- NANOTECH POLAND 2016 Conference and Exhibition (year: 2016, pages: 144), Publisher: Centrum NanoBioMedyczne Uniwersytetu im . Adama Mickiewicza w Poznaniu
- Date:
- conference 22-25 czerwca
- Status:
- Published
-
Composites of Nucleic Acids and Oligofunctionalized Carboranes: synthesis, physicochemical and biological properties
- Authors:
- D. Kaniowski, K. Ebenryter-Olbińska, K. Kulik, M. Sobczak, S. Janczak, Z. J. Leśnikowski, B. Nawrot
- Conference:
- XX International Symposium Advances in the Chemistry of Heteroorganic Compounds (year: 2018, pages: P-118), Publisher: CBMM PAN, PTCh
- Date:
- conference 46349
- Status:
- Published
-
Effect of boron cluster substitution on electronic properties of purine chromophore in adenosine nucleosides
- Authors:
- Aleksandra Kierozalska, Carla Sardo, Zbigniew J. Lenikowski
- Conference:
- XXI International Symposium Advances in the Chemistry of Heteroorganic Compounds (year: 2018, pages: P-039), Publisher: CBMM PAN, PTCh
- Date:
- conference 46349
- Status:
- Published
-
Post-synthetic modification of DNA-oligonucleotides with boron clusters using click chemistry methodology
- Authors:
- K. Ebenryter-Olbińska, Z.J. Leśnikowski, B. Nawrot
- Conference:
- 59 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2016, pages: 88 S01P33), Publisher: Uniwersytet im. Adama Mickiewicza
- Date:
- conference 19-23 września
- Status:
- Published
-
Oligopods of antisense oligonucleotides with boron clusters: self-assembly and biological properties
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Katarzyna Kulik, Milena Sobczak, Sławomir Janczak, Zbigniew J. Leśnikowski, Barbara Nawrot
- Conference:
- XXIII International Roundtable on Nucleosides, Nucleotides and Nucleic Acids (year: 2018, pages: P-168), Publisher: UC San Diego
- Date:
- conference August 26-30
- Status:
- Published
-
Optimization of click reaction conditions on solid support for synthesis of oligofunctionalized carboranes
- Authors:
- K. Kulik, A. Maciaszek, Z. J. Leśnikowski, B. Nawrot
- Conference:
- XX International Symposium Advances in the Chemistry of Heteroorganic Compounds (year: 2018, pages: P-117), Publisher: CBMM, PAN, PTCh
- Date:
- conference 46349
- Status:
- Published
-
Nowe metody funkcjonalizacji klasterów boru i ich wykorzystanie do syntezy biokoniugatów
- Authors:
- S. Janczak, ZJ. Leśnikowski
- Conference:
- 60 Zjazd PTCh (year: 2017, pages: 591), Publisher: PTCh
- Date:
- conference 17-21 września
- Status:
- Published
-
Antiviral effect of non-functionalized gold nanoparticles against herpes simplex virus type 1 (HSV-1)
- Authors:
- Leśnikowski Z., Paradowska E., Studzińska M., Lozovski V., Rusinchuk N., Mukha Iu., Vityuk N.
- Conference:
- Nanotechnology and Nanomaterials (NANO-2018) (year: 2018, pages: 8), Publisher: National Academy of Sciences of Ukraine
- Date:
- conference 27-30 August
- Status:
- Published
-
Unusual resistance of metallacarborane O-(4-nitrophenyl)-phosphorothioate ester towards alkali hydrolysis
- Authors:
- Carla Sardo, Zbigniew Leśnikowski
- Conference:
- PBSi 2018 International Conference on Phosphorus, Boron and Silicon (year: 2018, pages: 148), Publisher: PremC
- Date:
- conference December 10-12
- Status:
- Published
-
Application of boron clusters in nanoconstruction – present and future
- Authors:
- Leśnikowski Z.J.
- Conference:
- Nanotechnology and Nanomaterials (NANO-2018) (year: 2018, pages: 394-395), Publisher: National Academy of Sciences of Ukraine
- Date:
- conference 27-30 August
- Status:
- Published
-
Composites of DNA and boron clusters and their assembly into functional nanoparticles
- Authors:
- Katarzyna Ebenryter-Olbińska, Krzysztof Śmiałkowski, Carla Sardo, Damian Kaniowski, Gabriela Gajek, Katarzyna Bednarska-Szczepaniak, Lidia Żukowska, Barbara Nawrot and Zbigniew J. Leśnikowski
- Conference:
- 9th European Conference on Boron Chemistry (year: 2022, pages: 21), Publisher: ICMAB and CSIC
- Date:
- conference 3-7 lipca
- Status:
- Published
-
Oligofunkcjonalizacja metalokarboranów - Synteza pochodnych bis(1,2-dikarba-closo-undekaborano)-commo-3,3'-kobaltanu (III) (-1) podstawionych równocześnie na atomach węgla i boru
- Authors:
- Krzysztof Śmiałkowski, Zbigniew Leśnikowski
- Conference:
- VIII Ogólnopolskie Seminarium Postępy w Chemii Boru (year: 2022, pages: 18), Publisher: Politechnika Warszawska
- Date:
- conference 3-5 czerwca
- Status:
- Published
-
Highly boron-loaded antisense oligonucleotides conjugated with target-directed ligands for dual anticancer therapy: anti-EGFR and BNCT
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Justyna Suwara, Agata Jakóbik-Kolon, Anna Maciaszek, Barbara nawrot
- Conference:
- 9th European Conference on Boron Chemistry (year: 2022, pages: 127), Publisher: ICMAB and CSIC
- Date:
- conference 3-7 lipca
- Status:
- Published
-
Antisense oligonucleotides conjugated with boron clusters as a dual-action therapeutic platform: anti-EGFR in cancer cells and BNCT
- Authors:
- Damian Kaniowski, Katarzyna Ebenryter-Olbinska, Justyna Suwara, Agata Jakóbik-Kolon, Anna Maciaszek, Barbara Nawrot
- Conference:
- 8th Central European Congress of Life Sciences EUROBIOTECH (year: 2022, pages: O11), Publisher: EXPO
- Date:
- conference 20-22 czerwiec
- Status:
- Published
-
Oligofunctionalization of cobalt-bis(1,2-dicarbollide)ate (COSAN) as a building block for nanoconstruction
- Authors:
- Krzysztof Śmiałkowski, Carla Sardo, Zbigniew Leśnikowskii
- Conference:
- 9th European Conference on Boron Chemistry (year: 2022, pages: 150), Publisher: ICMAB and CSIC
- Date:
- conference 3-7 lipca
- Status:
- Published
-
Oligofunkcjonalizacja klasterów boru jako bloków budulcowych nowych materiałów oraz związków bioaktywnych
- Authors:
- Krzysztof Śmiałkowski, Zbigniew Leśnikowski
- Conference:
- 63 Zjazd Polskiego Towarzystwa Chemicznego (year: 2021, pages: S01 KS04), Publisher: 63 PTCH
- Date:
- conference 2021-09-17-21
- Status:
- Published
-
Nanostructured conjugates of DNA oligonucleotides and boron clusters as potential dual-action anti-EGFR & BNCT therapeutics
- Authors:
- D.Kaniowski, K.Ebenryter-Olbińska, K.Kulik, A.Maciaszek, Z.J. Leśnikowski, B. Nawrot
- Conference:
- The 44th FEBS Congress (year: 2019, pages: 209), Publisher: FEBS PRESS
- Date:
- conference 6-11 July
- Status:
- Published
-
Unusual chirality of metallacarboranes containing phosphorothioate bridging moiety
- Authors:
- Krzysztof Śmiałkowski, Carla Sardo, Zbigniew Leśnikowski
- Conference:
- 23 International Conference on Phosphorus Chemistry (year: 2021, pages: P-099), Publisher: AJD
- Date:
- conference 2021-07-5-9
- Status:
- Published
Book publications / chapters in book publications (1)
-
Boron Clusters as Redox Labels for Nucleosides and Nucleic Acids
- Authors:
- Agnieszka B. Olejniczak and Zbigniew J. Leśnikowski
- Book:
- Handbook of Boron Science with Applications in Organometallics, Catalysis, Materials, and Medicine (year: 2018, volume: 4, pages: 46035), Publisher: World Scientific
- Status:
- Published