Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Impact of nanoparticles on cancer metastasis - epigenetic mechanisms

2014/15/B/NZ7/01036

Keywords:

silver nanoparticles gold nanoparticles nanoparticles functionalization tumor development SCID mice melanoma adenocarcinoma

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_2: Environment and health risks

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Wyższa Szkoła Informatyki i Zarządzania w Rzeszowie, Wydział Medyczny

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marcin Kruszewski 

Number of co-investigators in the project: 10

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 966 584 PLN

Project start date (Y-m-d): 2015-09-02

Project end date (Y-m-d): 2019-09-01

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. lodówko-zamrażarka (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Comet assay in neural cells as a tool to monitor DNA damage induced by chemical or physical factors relevant to environmental and occupational exposure
    Authors:
    Kruszewski M, Sikorska K, Meczynska-Wielgosz S, Grzelak A, Sramkova M, Gabelova A, Kapka-Skrzypczak L.
    Academic press:
    Mutation Research - Genetic Toxicology and Environmental Mutagenesis (rok: 2019, tom: 845, strony: 402990), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mrgentox.2018.11.014 - link to the publication
  2. Effect of nanoparticles on the expression and activity of matrix metalloproteinases
    Authors:
    Matysiak-Kucharek M, Czajka M, Sawicki K, Kruszewski M, Kapka-Skrzypczak L.
    Academic press:
    Nanotechnology Reviews (rok: 2018, tom: 7(6), strony: 541–553), Wydawca: De Gruyter
    Status:
    Published
    DOI:
    10.1515/ntrev-2018-0110 - link to the publication
  3. Toxicity of metallic nanoparticles in the central nervous system
    Authors:
    Krzysztof Sawicki*, Magdalena Czajka, Magdalena Matysiak-Kucharek, Berta Fal, Bartłomiej Drop, Sylwia Męczyńska-Wielgosz, Katarzyna Sikorska, Marcin Kruszewski, Lucyna Kapka-Skrzypczak
    Academic press:
    Nanotechnology Reviews (rok: 2019, tom: 8, strony: 175-200), Wydawca: De Gruyter
    Status:
    Published
    DOI:
    10.1515/ntrev-2019-0017 - link to the publication
  4. Transient Vasodilation in Mouse 4T1 Tumors after Intragastric and Intravenous Administration of Gold Nanoparticles
    Authors:
    Brzoska, K., Szczygiel, M., Drzał, A., Sniegocka, M., Michalczyk-Wetula, D., Biela, E., Elas, M., Kapka-Skrzypczak, L., Lewandowska-Siwkiewicz, H., Urbanska, K., Kruszewski, M
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2361), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22052361 - link to the publication
  5. Crucial role of chelatable iron in silver nanoparticles induced DNA damage and cytotoxicity
    Authors:
    Grzelak A, Wojewódzka M, Meczynska-Wielgosz S, Zuberek M, Wojciechowska D, Kruszewski M.
    Academic press:
    Redox Biology (rok: 2018, tom: 15, strony: 435-440), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.redox.2018.01.006 - link to the publication

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