Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Translation elongation as a target for regulation by non-coding RNAs in bacteria

2014/15/B/NZ1/03330

Keywords:

ribosome translation elongation frameshifting Hfq bacterial non-coding RNA

Descriptors:

  • NZ1_2:
  • NZ1_1:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mikołaj Olejniczak 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 1 013 270 PLN

Project start date (Y-m-d): 2015-07-20

Project end date (Y-m-d): 2019-07-19

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. zamrazarka -80C (45 000 PLN)
  2. system do detekcji metodą Western wraz z zasilaczem (30 000 PLN)
  3. autoklaw stolowy (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. The binding of Class II sRNA MgrR to two different sites on matchmaker protein Hfq enables efficient competition for Hfq and annealing to regulated mRNAs
    Authors:
    Joanna Kwiatkowska, Zuzanna Wroblewska, Kenneth A. Johnson, Mikolaj Olejniczak
    Academic press:
    RNA (rok: 2018, tom: 24, strony: 1761-1784), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1261/rna.067777 - link to the publication
  2. Contributions of the Hfq protein to translation regulation by small noncoding RNAs binding to the mRNA coding sequence
    Authors:
    Wroblewska Z, Olejniczak M.
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 701-701), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    10.18388/abp.2016_1362 - link to the publication
  3. ProQ/FinO-domain proteins: another ubiquitous family of RNA matchmakers?
    Authors:
    Olejniczak M., Storz G.
    Academic press:
    Molecular Microbiology (rok: 2017, tom: 104, strony: 905-915), Wydawca: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/mmi.13679 - link to the publication
  4. Contributions of the Hfq protein to translation regulation by small noncoding RNAs binding to the mRNA coding sequence
    Authors:
    Wroblewska Z, Olejniczak M.
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 701-701), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    10.18388/abp.2016_1362 - link to the publication
  5. Determinants of RNA recognition by the FinO domain of the Escherichia coli ProQ protein.
    Authors:
    Stein EM, Kwiatkowska J, Basczok MM, Gravel CM, Berry KE, Olejniczak M.
    Academic press:
    Nucleic Acids Research (rok: 2020, tom: 48, strony: 7502-7519), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkaa497 - link to the publication
  6. The structure of fadL mRNA and its interactions with RybB sRNA
    Authors:
    Groszewska A, Wroblewska Z, Olejniczak M.
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 835-840), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    0.18388/abp.2016_1361 - link to the publication