Translation elongation as a target for regulation by non-coding RNAs in bacteria

2014/15/B/NZ1/03330

Keywords

Descriptors

  • NZ1_2: Biochemia
  • NZ1_1: Biologia molekularna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Mikołaj Olejniczak

Number of co-investigators in the project: 6

Call

OPUS 8 – announced on 2014-09-15

Amount awarded
1 013 270 PLN
Project start date
2015-07-20
Project end date
2019-07-19
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. autoklaw stolowy. Cost: 5 000 PLN
  2. system do detekcji metodą Western wraz z zasilaczem. Cost: 30 000 PLN
  3. zamrazarka -80C. Cost: 45 000 PLN

Information in the final report

Publication in academic press/journals (5)

  1. Contributions of the Hfq protein to translation regulation by small noncoding RNAs binding to the mRNA coding sequence

    Authors:
    Wroblewska Z, Olejniczak M.
    Academic press:
    Acta Biochimica Polonica (year: 2016, volume: 63, pages: 701-701), Publisher: Polish Biochemical Society
    Status:
    Published
    DOI:
    10.18388/abp.2016_1362 – link to the publication
  2. The structure of fadL mRNA and its interactions with RybB sRNA

    Authors:
    Groszewska A, Wroblewska Z, Olejniczak M.
    Academic press:
    Acta Biochimica Polonica (year: 2016, volume: 63, pages: 835-840), Publisher: Polish Biochemical Society
    Status:
    Published
    DOI:
    link to the publication
  3. Determinants of RNA recognition by the FinO domain of the Escherichia coli ProQ protein.

    Authors:
    Stein EM, Kwiatkowska J, Basczok MM, Gravel CM, Berry KE, Olejniczak M.
    Academic press:
    Nucleic Acids Research (year: 2020, volume: 48, pages: 7502-7519), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkaa497 – link to the publication
  4. The binding of Class II sRNA MgrR to two different sites on matchmaker protein Hfq enables efficient competition for Hfq and annealing to regulated mRNAs

    Authors:
    Joanna Kwiatkowska, Zuzanna Wroblewska, Kenneth A. Johnson, Mikolaj Olejniczak
    Academic press:
    RNA (year: 2018, volume: 24, pages: 1761-1784), Publisher: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1261/rna.067777 – link to the publication
  5. ProQ/FinO-domain proteins: another ubiquitous family of RNA matchmakers?

    Authors:
    Olejniczak M., Storz G.
    Academic press:
    Molecular Microbiology (year: 2017, volume: 104, pages: 905-915), Publisher: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/mmi.13679 – link to the publication

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