Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Translation elongation as a target for regulation by non-coding RNAs in bacteria

2014/15/B/NZ1/03330

Keywords:

ribosome translation elongation frameshifting Hfq bacterial non-coding RNA

Descriptors:

  • NZ1_2: Biochemistry
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mikołaj Olejniczak 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 1 013 270 PLN

Project start date (Y-m-d): 2015-07-20

Project end date (Y-m-d): 2019-07-19

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. zamrazarka -80C (45 000 PLN)
  2. system do detekcji metodą Western wraz z zasilaczem (30 000 PLN)
  3. autoklaw stolowy (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Determinants of RNA recognition by the FinO domain of the Escherichia coli ProQ protein.
    Authors:
    Stein EM, Kwiatkowska J, Basczok MM, Gravel CM, Berry KE, Olejniczak M.
    Academic press:
    Nucleic Acids Research (rok: 2020, tom: 48, strony: 7502-7519), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkaa497 - link to the publication
  2. Contributions of the Hfq protein to translation regulation by small noncoding RNAs binding to the mRNA coding sequence
    Authors:
    Wroblewska Z, Olejniczak M.
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 701-701), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    10.18388/abp.2016_1362 - link to the publication
  3. The binding of Class II sRNA MgrR to two different sites on matchmaker protein Hfq enables efficient competition for Hfq and annealing to regulated mRNAs
    Authors:
    Joanna Kwiatkowska, Zuzanna Wroblewska, Kenneth A. Johnson, Mikolaj Olejniczak
    Academic press:
    RNA (rok: 2018, tom: 24, strony: 1761-1784), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1261/rna.067777 - link to the publication
  4. The structure of fadL mRNA and its interactions with RybB sRNA
    Authors:
    Groszewska A, Wroblewska Z, Olejniczak M.
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 835-840), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    0.18388/abp.2016_1361 - link to the publication
  5. Bacterial chaperone protein Hfq facilitates the annealing of sponge RNAs to small regulatory RNAs
    Authors:
    Ewelina M. Małecka, Daria Sobańska, Mikołaj Olejniczak
    Academic press:
    Journal of Molecular Biology (rok: 2021, tom: brak, strony: brak), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    10.1101/2021.04.25.441314 - link to the publication
  6. ProQ/FinO-domain proteins: another ubiquitous family of RNA matchmakers?
    Authors:
    Olejniczak M., Storz G.
    Academic press:
    Molecular Microbiology (rok: 2017, tom: 104, strony: 905-915), Wydawca: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/mmi.13679 - link to the publication

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