Projects funded by the NCN
Modulation of mitochondrial calcium traffic in pink1 mutant Zebrafish model of Parkinson's disease
2014/15/D/NZ3/05176
Keywords:
Parkinson's disease mutant pink1 mitochondria Ca2+ Zebrafish
Descriptors:
- NZ3_6: Cell neurobiology
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Międzynarodowy Instytut Biologii Molekularnej i Komórkowej
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 1
Call: SONATA 8 - announced on 2014-09-15
Amount awarded: 583 437 PLN
Project start date (Y-m-d): 2015-08-12
Project end date (Y-m-d): 2018-08-11
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Zestaw hodowlany Danio rerio (25 000 PLN)
Information in the final report
- Publication in academic press/journals (2)
- Inhibition of the mitochondrial calcium uniporter (MCU) rescues dopaminergic neurons in pink1-/-zebrafishAuthors:Soman, S., Keatinge, M., Moein, M., DaCosta, M., Mortiboys, H., Skupin, A., Sugunan, S., Bazala, M., Kuznicki, J. and Bandmann, O.Academic press:European Journal of Neuroscience (rok: 2017, tom: 45, strony: 528-535), Wydawca: Wiley-BlackwellStatus:PublishedDOI:10.1111/ejn.13473 - link to the publication
- Restriction of mitochondrial calcium overload by mcu inactivation renders neuroprotective effect in zebrafish models of AQ1 Parkinson's diseaseAuthors:Smijin K. Soman, Michal Bazała, Marcus Keatinge, Oliver Bandmann and Jacek KuznickiAcademic press:Biology Open (rok: 2019, tom: 8, strony: 45303), Wydawca: The Company of Biologists LtdStatus:PublishedDOI:10.1242/bio.044347 - link to the publication