Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Self-organizing systems based on polymeric surfactants and lipid formulations; characteristics and their role in the formation of stable complexes with nucleic acids

2014/15/N/ST5/02003

Keywords:

lipoplexes polymeric surfactants DNA gene therapy

Descriptors:

  • ST5_12: Methods of nanomaterials/materials synthesis
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Żaneta Polańska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 8 - announced on 2014-09-15

Amount awarded: 133 600 PLN

Project start date (Y-m-d): 2015-09-25

Project end date (Y-m-d): 2019-09-24

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. mikro-przystawka ATR z kryształem diamentowym (22 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (5)
  1. Clear distinction between CAC and CMC revealed by high-resolution NMR diffusometry for a series of bis-imidazolium gemini surfactants in aqueous solutions
    Authors:
    Kosma Szutkowski, Żaneta Kołodziejska, Zuzanna Pietralik, Igor Zhukov, Andrzej Skrzypczak, Katarzyna Materna, Maciej Kozak
    Academic press:
    RSC Advances (rok: 2018, tom: 8, strony: 38470-38482), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8RA07081D - link to the publication
  2. The Process of Binding and Releasing of Genetic Material from Lipoplexes Based on Trimeric Surfactants and Phospholipids
    Authors:
    Żaneta Polańska, Zuzanna Pietralik-Molińska, Daria Wojciechowska, Augustyn Moliński, Marek Weiss, Andrzej Skrzypczak, Maciej Kozak
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 7744), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22147744 - link to the publication
  1. Systems based on trimetric surfactants and lipids as nonviral vector for gene therapy
    Authors:
    Żaneta Kołodziejska, Zuzanna Pietralik, Maciej Kozak
    Conference:
    KSUPS 2017 (rok: 2017, ), Wydawca: Polish Synchrotron Radiation Society
    Data:
    konferencja 04-07.09.2017
    Status:
    Published
  2. TRIMERIC SURFACTANTS AS NEW EFFECTIVE VECTORS FOR GENE THERAPY
    Authors:
    Żaneta Kołodziejska, Zuzanna Pietralik, Maciej Kozak
    Conference:
    X-Ray Investigations of Polymer Structure XIPS 2016 (rok: 2016, ), Wydawca: Wyd. Naukowe Akademia Techniczno-Humanistyczna
    Data:
    konferencja 06-09.12.2016
    Status:
    Published
  3. The aggregation in the transition region studied for monomeric and dimeric gemini surfactants
    Authors:
    K. Szutkowski, Ż. Kołodziejska, M. Banaszak, R.J. Spontak, R. Markiewicz
    Conference:
    Ampere NMR School (rok: 2018, ), Wydawca: NanoBioMedical Centre and Faculty of Physics UAM Poznan
    Data:
    konferencja 10-16.06.2018
    Status:
    Published
  4. Układy na bazie surfaktantów trigemini i formulacji lipidowych jako efektywne i innowacyjne nośniki dla terapii genowej
    Authors:
    Ż. Kołodziejska, Z. Pietralik, M. Kozak
    Conference:
    IX Seminarium Badania prowadzone metodami skaningowej mikroskopii bliskich oddziaływań STM/AFM 2016 (rok: 2016, ), Wydawca: NANOSAM
    Data:
    konferencja 30.11- 4.12.2016
    Status:
    Published
  5. Complexes based on trigemini surfactants and natural lipids as new effective carriers for gene therapy
    Authors:
    Ż. Kołodziejska, Z. Pietralik, M. Weiss, M. Kozak
    Conference:
    13th International School and Symposium on Synchrotron Radiation in Natural Science (ISSRNS 2016), Ustroń (rok: 2016, ), Wydawca: Polish Synchrotron Radiation Society
    Data:
    konferencja 13-18.06.2016
    Status:
    Published