Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of intercellular interactions involving Fgf4/MAPK signalling pathway in regulation of development of mouse chimaeric embryo

2014/15/D/NZ3/02435

Keywords:

chimaera embryonic stem cells embryo blastocyst intercellular interactions

Descriptors:

  • NZ3_13: Developmental biology in animals
  • NZ3_8: Stem cell biology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aneta Suwińska 

Number of co-investigators in the project: 3

Call: SONATA 8 - announced on 2014-09-15

Amount awarded: 649 400 PLN

Project start date (Y-m-d): 2015-08-10

Project end date (Y-m-d): 2019-08-09

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. komputer wraz z monitorem, klawiaturą, myszką.
  2. oprogramowanie IMARIS Track (40 000 PLN)
  3. Dysocjator do tkanek (40 000 PLN)
  4. Oprogramowanie Imaris; moduły: Core, MeasurementPro, Track.

Information in the final report

  • Publication in academic press/journals (5)
  1. FGF/ERK signaling pathway: how it operates in mammalian preimplantation embryos and embryo-derived stem cells
    Authors:
    Soszyńska A., Klimczewska K., Suwińska A.
    Academic press:
    International Journal of developmental Biology (rok: 2019, tom: 63, strony: 171-186), Wydawca: UPV/EHU Press
    Status:
    Published
    DOI:
    10.1387/ijdb.180408as - link to the publication
  2. Multi-level Fgf4- and apoptosis-dependent regulatory mechanism ensures the plasticity of ESC-chimaeric mouse embryo
    Authors:
    Soszyńska A., Filimonow K., Wigger M., Wołukanis K., Gross A., Szczepańska K. and Suwińska A.
    Academic press:
    Development (rok: 2023, tom: 150 (14), strony: dev201756), Wydawca: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/dev.201756 - link to the publication
  3. Exposure of chimaeric embryos to exogenous FGF4 leads to the production of pure ESCs-derived mice
    Authors:
    Soszyńska Anna, Krawczyk Katarzyna, Szpila Marcin, Winek Eliza, Szpakowska Anna, Suwińska Aneta
    Academic press:
    Reproduction (rok: 2023, tom: -, strony: -), Wydawca: Society for Reproduction and Fertility
    Status:
    Submitted
  4. The regulative nature of mammalian embryos
    Authors:
    Klimczewska K., Kasperczuk A., Suwińska A.
    Academic press:
    Current topics in developmental biology (rok: 2018, tom: 128, strony: 105-149), Wydawca: Elsevier
    Status:
    Published
  5. Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of Fgf/MAPK pathway
    Authors:
    Wigger M., Kisielewska K., Filimonow K., Plusa B., Maleszewski M., Suwińska A.
    Academic press:
    Scientific Reports (rok: 2017, tom: 7(1), strony: 15136), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-017-15427-0 - link to the publication