Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Immunomodulatory effects of sildenafil citrate in women with recurrent pregnancy loss

2014/15/D/NZ7/01838

Keywords:

sildenafil,Nk cells recurrent pregnancy loss with unexplain reason

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Monika Kniotek 

Number of co-investigators in the project: 6

Call: SONATA 8 - announced on 2014-09-15

Amount awarded: 389 560 PLN

Project start date (Y-m-d): 2015-08-10

Project end date (Y-m-d): 2020-05-09

Project duration:: 57 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Instalacja i szkolenie z obsługi Bricubator MIC-101 (500 PLN)
  2. Podwójny miernik przeplywu gazów-DFM 3002 (2 405 PLN)
  3. Brinkubator-komora modulująca warunki hodowli-MIC 101 (2 475 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Decreased Production of TNF-α and IL-6 Inflammatory Cytokines in Non-Pregnant Idiopathic RPL Women Immunomodulatory Effect of Sildenafil Citrate on the Cellular Response of Idiopathic RPL Women
    Authors:
    Monika Kniotek, Michał Zych, Aleksander Roszczyk, Monika Szafarowska, Małgorzata Jerzak
    Academic press:
    Journal of Clinical Medicine (rok: 2021, tom: 10(14), strony: 3115), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10143115 - link to the publication
  2. Differences in the Expression of KIR, ILT Inhibitory Receptors, and VEGF Production in the Induced Decidual NK Cell Cultures of Fertile and RPL Women
    Authors:
    Monika Kniotek , Aleksander Roszczyk , Michał Zych , Monika Szafarowska , Małgorzata Jerzak
    Academic press:
    BioMed Research International (rok: 2021, tom: 2021, strony: Article ID 6673427), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2021/6673427 - link to the publication
  3. Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients
    Authors:
    Monika Kniotek, Agnieszka Boguska
    Academic press:
    Journal of Immunology Research (rok: 2017, tom: 2017, strony: 8, Article ID 4541958), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2017/4541958 - link to the publication
  4. Sildenafil Citrate Influences Production of TNF-α in Healthy Men Lymphocytes
    Authors:
    Michał Zych,1 Aleksander Roszczyk,1 Monika Kniotek ,1 Beata Kaleta ,1 and Radoslaw Zagozdzon 1,2
    Academic press:
    Journal of Immunology Research (rok: 2019, tom: 2019, strony: 6), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2019/8478750 - link to the publication
  5. Differences in immune checkpoints expression (TIM-3 and PD-1) on T cells in women with recurrent miscarriages - preliminary studies
    Authors:
    Michał Zych, Aleksander Roszczyk, Monika Kniotek, Filip Dąbrowski Radosław Zagożdżon
    Academic press:
    Journal of Clinical Medicine , Wydawca: MDPI
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy