Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The impact of circulating monocyte-platelete aggregates and platelet derived microparticles on the stroke pathophysiology, treatment and outcome.

2014/15/B/NZ4/00736

Keywords:

stroke platelets platelet derived microparticles monocyte-platelet complexes

Descriptors:

  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Maria Łukasik 

Number of co-investigators in the project: 3

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 781 408 PLN

Project start date (Y-m-d): 2015-08-06

Project end date (Y-m-d): 2019-08-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Agregometr Multiplate (59 400 PLN)
  2. Mikrowirówka z chłodzeniem (22 140 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (4)
  1. Association between platelet-derived microparticles and their phenotypes with high on-treatment platelet reactivity and recurrent vascular events in convalescent stroke patients treated with acetylsalicylic acid
    Authors:
    Rosinska J., Maciejewska J., Narożny R., Kozubski W., Łukasik M.
    Academic press:
    Wiadomości Lekarskie (rok: 2019, tom: LXXII, nr 8, strony: 1427-37), Wydawca: Polskie Towarzystwo Lekarskie
    Status:
    Published
  2. The impact of vascular disease treatment on platelet-derived microvesicles
    Authors:
    Rosinska J., Łukasik M., Kozubski W.
    Academic press:
    Cardiovasc Drugs Ther (rok: 2017, tom: Vol. 31, strony: 627-644,), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10557-017-6757-7 - link to the publication
  3. Association of platelet-derived microvesicles and their phenotypes with carotid atherosclerosis and recurrent vascular events in patients after ischemic stroke
    Authors:
    Rosinska J., Ambrosius W., MaciejewskaJ., Narożny R., Kozubski W., Łukasik M
    Academic press:
    Thrombosis Research (rok: 2019, tom: 176, strony: 18-26), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.thromres.2019.01.014 - link to the publication
  4. Effect of acetylsalicylic acid intake on platelet derived microvesicles in healthy subjects
    Authors:
    Rosinska J., Maciejewska J., Narożny R., Osztynowicz K., Raczak B., Michalak S., Watała C., Kozubski W., Łukasik M.
    Academic press:
    Platelets (rok: 2019, tom: 45372, strony: 45300), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/09537104.2019.1588242 - link to the publication
  1. High residual platelet reactivity in patients after thrombotic stroke treated with aspirin
    Authors:
    Justyna Rosińska, Maria Łukasik, Robert Narożny, Wojciech Ambrosius, Cezary Watała, Wojciech Kozubski
    Conference:
    27th European Stroke Conference. Athens, Greece (rok: 2018, ), Wydawca: Cerebrovasc Dis, Karger
    Data:
    konferencja 11-13.04.2018
    Status:
    Published
  2. Diapedetic Potential of Monocytes in Complexes with Platelets Correlates with Clinical Outcome after Stroke
    Authors:
    Maria Lukasik, Radoslaw Kazmierski, Natalia Andrzejewska, Jacek Aniola, Maria Kamieniarz, Justyna Rosinska, Maciej Boruczkowski, Magdalena Frydrychowicz, Robert Narozny, Grzegorz Dworacki, Wojciech Kozubski
    Conference:
    70th Annual Meeting of American Academy of Neurology, Los Angeles, CA (rok: 2018, ), Wydawca: Neurology, Wolters Kluwer
    Data:
    konferencja 21-27.04.2018
    Status:
    Published
  3. Evaluation of platelet-derived microvesicles in patients after thrombotic stroke
    Authors:
    Justyna Rosińska, Maria Łukasik, Joanna Maciejewska, Robert Narożny, Wojciech Kozubski.
    Conference:
    4th Congress of the European Academy of Neurology. Lisbon, Portugal (rok: 2018, ), Wydawca: Eur J Neurol, Wiley Online Library
    Data:
    konferencja 16-19.06.2018
    Status:
    Published
  4. The effect of aspirin daily dose change on platelet-derived microvesicles in patients after ischaemic stroke
    Authors:
    Justyna Rosińska, Maria Łukasik, Joanna Maciejewska, Robert Narożny, Wojciech Kozubski
    Conference:
    Annual Meeting of International Society for Extracellular Vesicles (ISEV) 2018. Barcelona, Spain (rok: 2018, ), Wydawca: Journal of Extracellular Vesicles, Taylor&Francis Online
    Data:
    konferencja 2-6.05.2018
    Status:
    Published