Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Regulation of metabolic processes of contractile proteins in heart subjected to oxidative stress.

2014/15/B/NZ3/04865

Keywords:

ischaemia/hypoxia reperfusion/reoxygenation cardiomyocytes MMP-2 post-translational modyfications

Descriptors:

  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Grzegorz Sawicki 

Number of co-investigators in the project: 4

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 1 057 050 PLN

Project start date (Y-m-d): 2015-07-15

Project end date (Y-m-d): 2019-07-14

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Drukarka.
  2. Graphpad (oprogramowanie).
  3. MS Office 2016.
  4. Łaźnia wodna z wytrząsaniem wraz z wyposażeniem.
  5. Notebook.
  6. MS Office Standard 2013.
  7. Moleculra Imager Chemi DocXRs+system with ImageLab 2.0 software, PC, 220V.
  8. System real-time do badania kurczliwości kardiomiocytów (362 850 PLN)
  9. Łaźnia wodna z systemem do cyrkulacji wody z wyposażeniem.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (4)
  1. A drug cocktail for protecting against ischemia-reperfusion injury
    Authors:
    ANNA KRZYWONOS-ZAWADZKA, MIECZYSŁAW WOŹNIAK, GRZEGORZ SAWICKI, [AUT. KORESP.] IWONA BIL-LULA
    Academic press:
    Frontiers in Bioscience-Landmark (rok: 2020, tom: 25, strony: 722-735), Wydawca: BRI
    Status:
    Published
    DOI:
    10.2741/4831 - link to the publication
  2. L-NAME improves doxycycline and ML-7 cardioprotection from oxidative stress
    Authors:
    Iwona Bil-Lula, Anna Krzywonos –Zawadzka, Jolanta Sawicka, Dariusz Bialy, Magdalena Wawrzynska, Mieczyslaw Wozniak, Grzegorz Sawicki
    Academic press:
    Frontiers in Bioscience (rok: 2018, tom: 23, strony: 298-309), Wydawca: Frontiers in Bioscience
    Status:
    Published
    DOI:
    10.2741/4592. - link to the publication
  3. Multidrug prevention or therapy of ischemia-reperfusion injury of the heart- mini review.
    Authors:
    Anna Krzywonos-Zawadzka, Aleksandra Franczak, Grzegorz Sawicki, Mieczysław Woźniak, Iwona Bil-Lula
    Academic press:
    Environmental Toxicology and Pharmacology (rok: 2017, tom: 55, strony: 55-59), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.etap.2017.08.004 - link to the publication
  1. Administration of exogenous iNOS inhibitor protects from ischemia/reperfusion heart injury in rat model
    Authors:
    Anna Krzywonos-Zawadzka, Aleksandra Franczak, Grzegorz Sawicki, Agnieszka Olejnik, Iwona Bil-Lula
    Conference:
    3rd Wroclaw Scientific Meetings (rok: 2019, ), Wydawca: Wydawnictwo Naukowe TYGIEL sp. z o.o.
    Data:
    konferencja 1-2.03.2019
    Status:
    Published
    DOI:
    link to the publication
  2. Co-administration of low concentrations of matrix metalloproteinase 2, myosin light chain kinase and nitric oxide synthase inhibitors protects heart from ischemia/reperfusion injury
    Authors:
    I. Bil-Lula, G. Sawicki, M. Wozniak, A. Krzywonos-Zawadzka,
    Conference:
    European Society of Cardiology Congress 2017 (rok: 2017, ), Wydawca: Oxford Academic, Eur.Heart J. 2017 Vol.38 suppl.1; s.1194-1195 poz.P5565
    Data:
    konferencja 26-30.08.2017
    Status:
    Published
    DOI:
    link to the publication
  3. An association between MMP-2, MMP-9, TIMP-4 and stable coronary artery disease, hypertension and diabetes
    Authors:
    Marta Banaszkiewicz, Wiktor Kuliczkowski, Iwona Bil-Lula
    Conference:
    3rdWroclaw Scientific Meetings (rok: 2019, ), Wydawca: Wydawnictwo Naukowe TYGIEL sp. z o.o.
    Data:
    konferencja 01-02.03.2019
    Status:
    Published
    DOI:
    link to the publication
  4. Mixture of MMP-2, MLCK and iNOS inhibitors protects from I/R heart injury in isolated rat heart model
    Authors:
    Anna Krzywonos-Zawadzka, Aleksandra Franczak, Grzegorz Sawicki, Agnieszka Olejnik, Iwona Bil-Lula
    Conference:
    3rd Wroclaw Scientific Meetings (rok: 2019, ), Wydawca: Wydawnictwo Naukowe TYGIEL sp. z o.o.,
    Data:
    konferencja 01-02.03.2019
    Status:
    Published
    DOI:
    link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy