Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of MANF in neuronal plasticity and neuroprotection

2014/15/B/NZ3/04754

Keywords:

Drosophila melanogaster plasticity of the nervous system circadian rhythms glial cells

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology
  • NZ3_4: Ageing

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Elżbieta Pyza 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 991 452 PLN

Project start date (Y-m-d): 2015-08-06

Project end date (Y-m-d): 2019-08-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw do dokumentacji żeli (20 000 PLN)
  2. Wirówka – Mini Plate Spinner (4 000 PLN)
  3. Inkubator do hodowli Drosophila melanogaster z kontrolą światła i temperatury.
  4. Inkubator do hodowli Drosophila melanogaster z kontrolą światła i temperatury. (60 000 PLN)
  5. Inkubator MIR-254-PE do hodowli Drosophila melanogaster z kontrolą światła i temperatury z osłoną na okno obserwacyjne i dodatkowymi półkami.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (10)
  1. Different Levels of Expression of the Clock Protein PER and the Glial Marker REPO in Ensheathing and Astrocyte-Like Glia of the Distal Medulla of Drosophila Optic Lobe
    Authors:
    Wojciech Krzeptowski, Lucyna Walkowicz, Alicja Płonczyńska, Jolanta Górska-Andrzejak
    Academic press:
    Frontiers in Physiology (rok: 2018, tom: 11, strony: 361), Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fphys.2018.00361 - link to the publication
  2. Downregulation of DmMANF in Glial Cells Results in Neurodegeneration and Affects Sleep and Lifespan in Drosophila melanogaster
    Authors:
    Walkowicz L, Kijak E, Krzeptowski W, Górska-Andrzejak J, Stratoulias V, Woznicka O, Chwastek E, Heino TI, Pyza EM
    Academic press:
    Frontiers in Neuroscience (rok: 2017, tom: 11, strony: 610), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnins.2017.00610 - link to the publication
  3. Glial expression of DmMANF is required for the regulation of activity, sleep and circadian rhythms in the visual system of Drosophila melanogaster.
    Authors:
    Walkowicz, L., Krzeptowski, W., Krzeptowska, E., Warzecha, K., Sałek, J., Górska‐Andrzejak, J.,Pyza, E.
    Academic press:
    European Journal of Neuroscience (rok: 2021, ), Wydawca: Federation of European Neuroscience Societies and John Wiley & Sons Ltd
    Status:
    Accepted for publication
    DOI:
    10.1111/ejn.15171 - link to the publication
  4. DmMANF regulates morphology of PDF-positive clock neurons and circadian neuronal plasticity in Drosophila melanogaster
    Authors:
    Wojciech Krzeptowski, Lucyna Walkowicz, Ewelina Krzeptowska, Edyta Motta, Kacper Witek, Joanna Szramel, Terence Al Abaquita, Zbigniew Baster, Zenon Rajfur, Ezio Rosato, Vassilis Stratoulias5, Tapio I. Heino, Elżbieta Pyza
    Academic press:
    Frontiers in Physiology , Wydawca: Frontiers
    Status:
    Submitted
  1. DmMANF is a neurotrophic factor crutial for development of clock neurons
    Authors:
    Krzeptowski W., Walkowicz L., Górska-Andrzejak J., Witek K., Warzecha K., Sałek J., Motta E., Pyza E.
    Conference:
    17th European Drosophila Beurobiology Conference (rok: 2018, ), Wydawca: 17th European Drosophila Beurobiology Conference
    Data:
    konferencja 3-7.09.2018
    Status:
    Published
  2. Distal medulla glia express mesencephalic astrocyte-derived neurotrophic factor that is crutial for circadian rhythms in Drosophila melanogaster
    Authors:
    Walkowicz L., Krzeptowski W., Witek K., Motta E., Szramel J., Warzecha K., Sałek J., Górska-Andrzejak J., Pyza E.
    Conference:
    17th European Drosophila Neurobiology Conference (rok: 2018, ), Wydawca: 17th European Drosophila Neurobiology Conference
    Data:
    konferencja 3-7.09.2018
    Status:
    Published
  3. DmMANF regulates behaviour of Drosophila melanogaster
    Authors:
    Walkowicz L, Krzeptowski W, Krzeptowska E, Witek K, Górska-Andrzejak J, Pyza E
    Conference:
    7th Conference Aspects of Neuroscience (rok: 2017, ), Wydawca: Uniwersytet Warszawski
    Data:
    konferencja 24-26.11.2017
    Status:
    Published
  4. Downregulation of DmMANF in clock neurons influences rhythmic behaviour of Drosophila melanogaster
    Authors:
    Walkowicz L., Krzeptowski W., Witek K., Szramel J., Warzecha K., Sałek J., Krzeptowska E., Górska-Andrzejak J., Pyza E.
    Conference:
    Neuronus 2018 IBRO Neuroscience Forum (rok: 2018, ), Wydawca: Neuronus 2018 IBRO Neuroscience Forum
    Data:
    konferencja 20-22.04.2018
    Status:
    Published
  5. DmMANF Regulates Behaviour of Drosophila melanogaster
    Authors:
    Walkowicz L., Krzeptowski W., Kijak E., Heino T., Pyza E.
    Conference:
    Neurofly 2016, 16th European Neurobiology of Drosophila Conference (rok: 2016, ), Wydawca: Neurofly 2016
    Data:
    konferencja 2-6.09.2016
    Status:
    Published
  6. Mesencephalic Astrocyte-derived Neurotrophic Factor is vital for endoplasmic reticulum and mitochondria and involved in unfolded protein response pathways.
    Authors:
    Warzecha .K, Walkowicz L., Krzeptowski W., Pyza E.
    Conference:
    4th International Conference of Cell Biology (rok: 2018, ), Wydawca: 4th International Conference of Cell Biology
    Data:
    konferencja 11-12.05.2018
    Status:
    Published
  7. The Role of DmMANF in the Visual System of Drosophila melanogaster and Circadian Plasticity
    Authors:
    Krzeptowski W., Walkowicz L., Kijak E., Górska-Andrzejak J., Stratoulias V., Heino T., Pyza E.
    Conference:
    Neurofly 2016, 16th European Neurobiology of Drosophila Conference (rok: 2016, ), Wydawca: Neurofly 2016
    Data:
    konferencja 2-6.09.2016
    Status:
    Published
  8. Localization and function of DmMANF in the visual system of Drosophila melanogaster
    Authors:
    Lucyna Walkowicz, Wojciech Krzeptowski, Ewelina Kijak, Jolanta Górska-Andrzejak, Elżbieta Pyza
    Conference:
    Imaging the Brain (rok: 2016, ), Wydawca: EMBO
    Data:
    konferencja 18-21.05.2016
    Status:
    Published
  9. Motor stimulation affects the level of synaptic proteins, expression of DmMANF neurotrophic factor and lifespan of Drosophila melanogaster
    Authors:
    Szramel J., Walkowicz L., Krzeptowski W., Pyza E.
    Conference:
    Neuronus 2018 IBRO Neuroscience Forum (rok: 2018, ), Wydawca: Neuronus 2018 IBRO Neuroscience Forum
    Data:
    konferencja 20-22.04.2018
    Status:
    Published
  10. Lokalizacja czynnika troficznego DmMANF oraz jego funkcja w mózgu Drosophila melanogaster
    Authors:
    Lucyna Walkowicz, Wojciech Krzeptowski, Ewelina Kijak, Jolanta Górska-Andrzejak, Elżbieta Pyza
    Conference:
    V Ogólnopolska Konferencja Młodych Naukowców Arthropod (rok: 2016, ), Wydawca: Wydział Biologii i Ochrony Środowiska, Uniwersytet Śląski W Katowicach
    Data:
    konferencja 01-03.07.2016
    Status:
    Published