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The role of MANF in neuronal plasticity and neuroprotection

2014/15/B/NZ3/04754

Keywords

Descriptors

  • NZ3_5: Neurobiologia molekularna
  • NZ3_6: Neurobiologia komórkowa
  • NZ3_4: Starzenie

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Uniwersytet Jagielloński, Wydział Biologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Elżbieta Małgorzata Pyza

Number of co-investigators in the project: 6

Call

OPUS 8 – announced on 2014-09-15

Amount awarded
991 452 PLN
Project start date
2015-08-06
Project end date
2019-08-05
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Inkubator MIR-254-PE do hodowli Drosophila melanogaster z kontrolą światła i temperatury z osłoną na okno obserwacyjne i dodatkowymi półkami.
  2. Inkubator do hodowli Drosophila melanogaster z kontrolą światła i temperatury.
  3. Inkubator do hodowli Drosophila melanogaster z kontrolą światła i temperatury.. Cost: 60 000 PLN
  4. Wirówka – Mini Plate Spinner. Cost: 4 000 PLN
  5. Zestaw do dokumentacji żeli. Cost: 20 000 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Downregulation of DmMANF in Glial Cells Results in Neurodegeneration and Affects Sleep and Lifespan in Drosophila melanogaster

    Authors:
    Walkowicz L, Kijak E, Krzeptowski W, Górska-Andrzejak J, Stratoulias V, Woznicka O, Chwastek E, Heino TI, Pyza EM
    Academic press:
    Frontiers in Neuroscience (year: 2017, volume: 11, pages: 610), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnins.2017.00610 – link to the publication

  2. Different Levels of Expression of the Clock Protein PER and the Glial Marker REPO in Ensheathing and Astrocyte-Like Glia of the Distal Medulla of Drosophila Optic Lobe

    Authors:
    Wojciech Krzeptowski, Lucyna Walkowicz, Alicja Płonczyńska, Jolanta Górska-Andrzejak
    Academic press:
    Frontiers in Physiology (year: 2018, volume: 11, pages: 361), Publisher: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fphys.2018.00361 – link to the publication

  3. Glial expression of DmMANF is required for the regulation of activity, sleep and circadian rhythms in the visual system of Drosophila melanogaster.

    Authors:
    Walkowicz, L., Krzeptowski, W., Krzeptowska, E., Warzecha, K., Sałek, J., Górska‐Andrzejak, J.,Pyza, E.
    Status:
    Accepted for publication

Articles in post-conference publications (10)

  1. Downregulation of DmMANF in clock neurons influences rhythmic behaviour of Drosophila melanogaster

    Authors:
    Walkowicz L., Krzeptowski W., Witek K., Szramel J., Warzecha K., Sałek J., Krzeptowska E., Górska-Andrzejak J., Pyza E.
    Conference:
    Neuronus 2018 IBRO Neuroscience Forum (year: 2018, pages: 119), Publisher: Neuronus 2018 IBRO Neuroscience Forum
    Date:
    conference 20-22.04.2018
    Status:
    Published

  2. Localization and function of DmMANF in the visual system of Drosophila melanogaster

    Authors:
    Lucyna Walkowicz, Wojciech Krzeptowski, Ewelina Kijak, Jolanta Górska-Andrzejak, Elżbieta Pyza
    Conference:
    Imaging the Brain (year: 2016, pages: 84), Publisher: EMBO
    Date:
    conference 18-21.05.2016
    Status:
    Published

  3. Lokalizacja czynnika troficznego DmMANF oraz jego funkcja w mózgu Drosophila melanogaster

    Authors:
    Lucyna Walkowicz, Wojciech Krzeptowski, Ewelina Kijak, Jolanta Górska-Andrzejak, Elżbieta Pyza
    Conference:
    V Ogólnopolska Konferencja Młodych Naukowców Arthropod (year: 2016, pages: 28), Publisher: Wydział Biologii i Ochrony Środowiska, Uniwersytet Śląski W Katowicach
    Date:
    conference 01-03.07.2016
    Status:
    Published

  4. The Role of DmMANF in the Visual System of Drosophila melanogaster and Circadian Plasticity

    Authors:
    Krzeptowski W., Walkowicz L., Kijak E., Górska-Andrzejak J., Stratoulias V., Heino T., Pyza E.
    Conference:
    Neurofly 2016, 16th European Neurobiology of Drosophila Conference (year: 2016, pages: 139), Publisher: Neurofly 2016
    Date:
    conference 2-6.09.2016
    Status:
    Published

  5. Mesencephalic Astrocyte-derived Neurotrophic Factor is vital for endoplasmic reticulum and mitochondria and involved in unfolded protein response pathways.

    Authors:
    Warzecha .K, Walkowicz L., Krzeptowski W., Pyza E.
    Conference:
    4th International Conference of Cell Biology (year: 2018, pages: 160), Publisher: 4th International Conference of Cell Biology
    Date:
    conference 11-12.05.2018
    Status:
    Published

  6. DmMANF is a neurotrophic factor crutial for development of clock neurons

    Authors:
    Krzeptowski W., Walkowicz L., Górska-Andrzejak J., Witek K., Warzecha K., Sałek J., Motta E., Pyza E.
    Conference:
    17th European Drosophila Beurobiology Conference (year: 2018, pages: 41), Publisher: 17th European Drosophila Beurobiology Conference
    Date:
    conference 3-7.09.2018
    Status:
    Published

  7. DmMANF Regulates Behaviour of Drosophila melanogaster

    Authors:
    Walkowicz L., Krzeptowski W., Kijak E., Heino T., Pyza E.
    Conference:
    Neurofly 2016, 16th European Neurobiology of Drosophila Conference (year: 2016, pages: 199), Publisher: Neurofly 2016
    Date:
    conference 2-6.09.2016
    Status:
    Published

  8. Distal medulla glia express mesencephalic astrocyte-derived neurotrophic factor that is crutial for circadian rhythms in Drosophila melanogaster

    Authors:
    Walkowicz L., Krzeptowski W., Witek K., Motta E., Szramel J., Warzecha K., Sałek J., Górska-Andrzejak J., Pyza E.
    Conference:
    17th European Drosophila Neurobiology Conference (year: 2018, pages: 45), Publisher: 17th European Drosophila Neurobiology Conference
    Date:
    conference 3-7.09.2018
    Status:
    Published

  9. Motor stimulation affects the level of synaptic proteins, expression of DmMANF neurotrophic factor and lifespan of Drosophila melanogaster

    Authors:
    Szramel J., Walkowicz L., Krzeptowski W., Pyza E.
    Conference:
    Neuronus 2018 IBRO Neuroscience Forum (year: 2018, pages: 116-117), Publisher: Neuronus 2018 IBRO Neuroscience Forum
    Date:
    conference 20-22.04.2018
    Status:
    Published

  10. DmMANF regulates behaviour of Drosophila melanogaster

    Authors:
    Walkowicz L, Krzeptowski W, Krzeptowska E, Witek K, Górska-Andrzejak J, Pyza E
    Conference:
    7th Conference Aspects of Neuroscience (year: 2017, pages: 140-141), Publisher: Uniwersytet Warszawski
    Date:
    conference 24-26.11.2017
    Status:
    Published

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