Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of MANF in neuronal plasticity and neuroprotection

2014/15/B/NZ3/04754

Keywords:

Drosophila melanogaster plasticity of the nervous system circadian rhythms glial cells

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology
  • NZ3_4: Ageing

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Elżbieta Pyza 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 991 452 PLN

Project start date (Y-m-d): 2015-08-06

Project end date (Y-m-d): 2019-08-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator MIR-254-PE do hodowli Drosophila melanogaster z kontrolą światła i temperatury z osłoną na okno obserwacyjne i dodatkowymi półkami.
  2. Inkubator do hodowli Drosophila melanogaster z kontrolą światła i temperatury. (60 000 PLN)
  3. Inkubator do hodowli Drosophila melanogaster z kontrolą światła i temperatury.
  4. Wirówka – Mini Plate Spinner (4 000 PLN)
  5. Zestaw do dokumentacji żeli (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (10)
  1. Different Levels of Expression of the Clock Protein PER and the Glial Marker REPO in Ensheathing and Astrocyte-Like Glia of the Distal Medulla of Drosophila Optic Lobe
    Authors:
    Wojciech Krzeptowski, Lucyna Walkowicz, Alicja Płonczyńska, Jolanta Górska-Andrzejak
    Academic press:
    Frontiers in Physiology (rok: 2018, tom: 11, strony: 361), Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fphys.2018.00361 - link to the publication
  2. Downregulation of DmMANF in Glial Cells Results in Neurodegeneration and Affects Sleep and Lifespan in Drosophila melanogaster
    Authors:
    Walkowicz L, Kijak E, Krzeptowski W, Górska-Andrzejak J, Stratoulias V, Woznicka O, Chwastek E, Heino TI, Pyza EM
    Academic press:
    Frontiers in Neuroscience (rok: 2017, tom: 11, strony: 610), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnins.2017.00610 - link to the publication
  3. Glial expression of DmMANF is required for the regulation of activity, sleep and circadian rhythms in the visual system of Drosophila melanogaster.
    Authors:
    Walkowicz, L., Krzeptowski, W., Krzeptowska, E., Warzecha, K., Sałek, J., Górska‐Andrzejak, J.,Pyza, E.
    Academic press:
    European Journal of Neuroscience (rok: 2021, ), Wydawca: Federation of European Neuroscience Societies and John Wiley & Sons Ltd
    Status:
    Accepted for publication
    DOI:
    10.1111/ejn.15171 - link to the publication
  4. DmMANF regulates morphology of PDF-positive clock neurons and circadian neuronal plasticity in Drosophila melanogaster
    Authors:
    Wojciech Krzeptowski, Lucyna Walkowicz, Ewelina Krzeptowska, Edyta Motta, Kacper Witek, Joanna Szramel, Terence Al Abaquita, Zbigniew Baster, Zenon Rajfur, Ezio Rosato, Vassilis Stratoulias5, Tapio I. Heino, Elżbieta Pyza
    Academic press:
    Frontiers in Physiology , Wydawca: Frontiers
    Status:
    Submitted
  1. DmMANF is a neurotrophic factor crutial for development of clock neurons
    Authors:
    Krzeptowski W., Walkowicz L., Górska-Andrzejak J., Witek K., Warzecha K., Sałek J., Motta E., Pyza E.
    Conference:
    17th European Drosophila Beurobiology Conference (rok: 2018, ), Wydawca: 17th European Drosophila Beurobiology Conference
    Data:
    konferencja 3-7.09.2018
    Status:
    Published
  2. Localization and function of DmMANF in the visual system of Drosophila melanogaster
    Authors:
    Lucyna Walkowicz, Wojciech Krzeptowski, Ewelina Kijak, Jolanta Górska-Andrzejak, Elżbieta Pyza
    Conference:
    Imaging the Brain (rok: 2016, ), Wydawca: EMBO
    Data:
    konferencja 18-21.05.2016
    Status:
    Published
  3. Mesencephalic Astrocyte-derived Neurotrophic Factor is vital for endoplasmic reticulum and mitochondria and involved in unfolded protein response pathways.
    Authors:
    Warzecha .K, Walkowicz L., Krzeptowski W., Pyza E.
    Conference:
    4th International Conference of Cell Biology (rok: 2018, ), Wydawca: 4th International Conference of Cell Biology
    Data:
    konferencja 11-12.05.2018
    Status:
    Published
  4. The Role of DmMANF in the Visual System of Drosophila melanogaster and Circadian Plasticity
    Authors:
    Krzeptowski W., Walkowicz L., Kijak E., Górska-Andrzejak J., Stratoulias V., Heino T., Pyza E.
    Conference:
    Neurofly 2016, 16th European Neurobiology of Drosophila Conference (rok: 2016, ), Wydawca: Neurofly 2016
    Data:
    konferencja 2-6.09.2016
    Status:
    Published
  5. Distal medulla glia express mesencephalic astrocyte-derived neurotrophic factor that is crutial for circadian rhythms in Drosophila melanogaster
    Authors:
    Walkowicz L., Krzeptowski W., Witek K., Motta E., Szramel J., Warzecha K., Sałek J., Górska-Andrzejak J., Pyza E.
    Conference:
    17th European Drosophila Neurobiology Conference (rok: 2018, ), Wydawca: 17th European Drosophila Neurobiology Conference
    Data:
    konferencja 3-7.09.2018
    Status:
    Published
  6. Downregulation of DmMANF in clock neurons influences rhythmic behaviour of Drosophila melanogaster
    Authors:
    Walkowicz L., Krzeptowski W., Witek K., Szramel J., Warzecha K., Sałek J., Krzeptowska E., Górska-Andrzejak J., Pyza E.
    Conference:
    Neuronus 2018 IBRO Neuroscience Forum (rok: 2018, ), Wydawca: Neuronus 2018 IBRO Neuroscience Forum
    Data:
    konferencja 20-22.04.2018
    Status:
    Published
  7. Lokalizacja czynnika troficznego DmMANF oraz jego funkcja w mózgu Drosophila melanogaster
    Authors:
    Lucyna Walkowicz, Wojciech Krzeptowski, Ewelina Kijak, Jolanta Górska-Andrzejak, Elżbieta Pyza
    Conference:
    V Ogólnopolska Konferencja Młodych Naukowców Arthropod (rok: 2016, ), Wydawca: Wydział Biologii i Ochrony Środowiska, Uniwersytet Śląski W Katowicach
    Data:
    konferencja 01-03.07.2016
    Status:
    Published
  8. DmMANF Regulates Behaviour of Drosophila melanogaster
    Authors:
    Walkowicz L., Krzeptowski W., Kijak E., Heino T., Pyza E.
    Conference:
    Neurofly 2016, 16th European Neurobiology of Drosophila Conference (rok: 2016, ), Wydawca: Neurofly 2016
    Data:
    konferencja 2-6.09.2016
    Status:
    Published
  9. DmMANF regulates behaviour of Drosophila melanogaster
    Authors:
    Walkowicz L, Krzeptowski W, Krzeptowska E, Witek K, Górska-Andrzejak J, Pyza E
    Conference:
    7th Conference Aspects of Neuroscience (rok: 2017, ), Wydawca: Uniwersytet Warszawski
    Data:
    konferencja 24-26.11.2017
    Status:
    Published
  10. Motor stimulation affects the level of synaptic proteins, expression of DmMANF neurotrophic factor and lifespan of Drosophila melanogaster
    Authors:
    Szramel J., Walkowicz L., Krzeptowski W., Pyza E.
    Conference:
    Neuronus 2018 IBRO Neuroscience Forum (rok: 2018, ), Wydawca: Neuronus 2018 IBRO Neuroscience Forum
    Data:
    konferencja 20-22.04.2018
    Status:
    Published