Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Mechanistic insight in Transmembrane Protein (TMEM) deregulation and its contribution to ccRCC etiology

2014/15/B/NZ2/00589

Keywords:

transmembrane proteins clear cell renal cell carcinoma next generation sequencing

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_7: Bioinformatics
  • NZ1_1: Molecular biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Joanna Wesoły 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 813 884 PLN

Project start date (Y-m-d): 2015-07-20

Project end date (Y-m-d): 2019-07-19

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. termocykler.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (7)
  1. Identification of RCC Subtype-Specific microRNAs-Meta-Analysis of High-Throughput RCC Tumor microRNA Expression Data
    Authors:
    Kajdasz A, Majer W, Kluzek K, Sobkowiak J, Milecki T, Derebecka N, Kwias Z, Bluyssen HAR, Wesoly J.
    Academic press:
    Cancers (rok: 2021, tom: 13(3):, strony: 548), Wydawca: Basel
    Status:
    Published
    DOI:
    0.3390/cancers13030548 - link to the publication
  2. Structural, topological, and functional characterization of transmembrane proteins TMEM213, 207, 116, 72 and 30B provides a potential link to ccRCC etiology
    Authors:
    Joanna Wesoly, Natalia Pstrąg, Kamil Derylo, Barbara Michalec-Wawiórka, Natalia Derebecka, Hanna Nowicka, Arkadiusz Kajdasz, Katarzyna Kluzek, Srebniak Małgorzata, Marek Tchórzewski, Zbigniew Kwias, Hans Bluyssen
    Academic press:
    American Journal of Cancer Research (rok: 2023, tom: brak, strony: brak), Wydawca: e-Century Publishing Corporation
    Status:
    Accepted for publication
  1. Subcellular localization of ccRCC biomarker candidates- TMEM72 and TMEM207 and the role of microRNAs in their regulation
    Authors:
    N. Pstrąg, A. Kajdasz, D. Niewiadomska, H.A.R.Bluyssen, J. Wesoly
    Conference:
    Transmambrane proteins in Health and Disease (rok: 2018, ), Wydawca: Canadian Society for Molecular Biosciences
    Data:
    konferencja 11-15.04
    Status:
    Published
  2. Analysis of splice variants of TMEM116 and their contribution to clear cell renal cell carcinoma (ccRCC) etiology
    Authors:
    N. Pstrąg, A. Kajdasz, HA. Bluyssen,. J. Wesoły
    Conference:
    IVth Międzynarodowa Konferencja Naukowo-Dydaktyczna Wydziału Biologii (rok: 2017, ), Wydawca: Wydawnictwo Kontekst
    Data:
    konferencja 06.04-08.04.2017
    Status:
    Published
  3. Landscape of RNA and protein processing of TMEMs in ccRCC
    Authors:
    N. Pstrag, A. Kajdasz,. H. Bluyssen, J. Wesoly
    Conference:
    Eurobiotech, 6th Central European Congress of Life Sciences (rok: 2017, ), Wydawca: Targi w Krakowie LTD
    Data:
    konferencja 11-14.09
    Status:
    Published
  4. Splice variants of TMEMs and their contribution to ccRCC etiology
    Authors:
    N. Pstrag, A. Kajdasz, J. Wesoly
    Conference:
    Post-transcriptional gene regulation (rok: 2017, ), Wydawca: Institut Curie
    Data:
    konferencja 27-31.03
    Status:
    Published
  5. Subcellular localization of ccRCC biomarker candidates- TMEM72 and TMEM207 and the role of microRNAs in their regulation
    Authors:
    D. Niewiadomska, A. Kajdasz, N. Pstrąg, H.A.R. Bluyssen, J. Wesoly
    Conference:
    EMBL Conference: From Functional Genomics to System Biology (rok: 2018, ), Wydawca: EMBL, Heidelberg, Germany
    Data:
    konferencja 10-13.11
    Status:
    Published
  6. Meta-analysis of the deregulated microRNAs in clear cell renal cell carcinoma
    Authors:
    A. Kajdasz, H.A.R. Bluyssen, J. Wesoly
    Conference:
    13th Microsymposium on Small RNAs (rok: 2018, ), Wydawca: nd
    Data:
    konferencja 18-20.06
    Status:
    Published
  7. Subcellular localization of TMEM116 depends on its alternative splicing - impact on clear cell renal cell carcinoma etiology
    Authors:
    A. Kajdasz, N. Pstrąg,D. Niewiadomska, H.A.R. Bluyssen, J. Wesoly
    Conference:
    Transmembrane Proteins in Health and Disease (rok: 2018, ), Wydawca: Canadian Society for Molecular Biosciences
    Data:
    konferencja 11-15.04
    Status:
    Published