Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Mechanistic insight in Transmembrane Protein (TMEM) deregulation and its contribution to ccRCC etiology

2014/15/B/NZ2/00589

Keywords:

transmembrane proteins clear cell renal cell carcinoma next generation sequencing

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_7: Bioinformatics
  • NZ1_1: Molecular biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Joanna Wesoły 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 813 884 PLN

Project start date (Y-m-d): 2015-07-20

Project end date (Y-m-d): 2019-07-19

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. termocykler.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (7)
  1. Identification of RCC Subtype-Specific microRNAs-Meta-Analysis of High-Throughput RCC Tumor microRNA Expression Data
    Authors:
    Kajdasz A, Majer W, Kluzek K, Sobkowiak J, Milecki T, Derebecka N, Kwias Z, Bluyssen HAR, Wesoly J.
    Academic press:
    Cancers (rok: 2021, tom: 13(3):, strony: 548), Wydawca: Basel
    Status:
    Published
    DOI:
    0.3390/cancers13030548 - link to the publication
  2. Structural, topological, and functional characterization of transmembrane proteins TMEM213, 207, 116, 72 and 30B provides a potential link to ccRCC etiology
    Authors:
    Joanna Wesoly, Natalia Pstrąg, Kamil Derylo, Barbara Michalec-Wawiórka, Natalia Derebecka, Hanna Nowicka, Arkadiusz Kajdasz, Katarzyna Kluzek, Srebniak Małgorzata, Marek Tchórzewski, Zbigniew Kwias, Hans Bluyssen
    Academic press:
    American Journal of Cancer Research (rok: 2023, tom: brak, strony: brak), Wydawca: e-Century Publishing Corporation
    Status:
    Accepted for publication
  1. Landscape of RNA and protein processing of TMEMs in ccRCC
    Authors:
    N. Pstrag, A. Kajdasz,. H. Bluyssen, J. Wesoly
    Conference:
    Eurobiotech, 6th Central European Congress of Life Sciences (rok: 2017, ), Wydawca: Targi w Krakowie LTD
    Data:
    konferencja 11-14.09
    Status:
    Published
  2. Splice variants of TMEMs and their contribution to ccRCC etiology
    Authors:
    N. Pstrag, A. Kajdasz, J. Wesoly
    Conference:
    Post-transcriptional gene regulation (rok: 2017, ), Wydawca: Institut Curie
    Data:
    konferencja 27-31.03
    Status:
    Published
  3. Analysis of splice variants of TMEM116 and their contribution to clear cell renal cell carcinoma (ccRCC) etiology
    Authors:
    N. Pstrąg, A. Kajdasz, HA. Bluyssen,. J. Wesoły
    Conference:
    IVth Międzynarodowa Konferencja Naukowo-Dydaktyczna Wydziału Biologii (rok: 2017, ), Wydawca: Wydawnictwo Kontekst
    Data:
    konferencja 06.04-08.04.2017
    Status:
    Published
  4. Meta-analysis of the deregulated microRNAs in clear cell renal cell carcinoma
    Authors:
    A. Kajdasz, H.A.R. Bluyssen, J. Wesoly
    Conference:
    13th Microsymposium on Small RNAs (rok: 2018, ), Wydawca: nd
    Data:
    konferencja 18-20.06
    Status:
    Published
  5. Subcellular localization of ccRCC biomarker candidates- TMEM72 and TMEM207 and the role of microRNAs in their regulation
    Authors:
    D. Niewiadomska, A. Kajdasz, N. Pstrąg, H.A.R. Bluyssen, J. Wesoly
    Conference:
    EMBL Conference: From Functional Genomics to System Biology (rok: 2018, ), Wydawca: EMBL, Heidelberg, Germany
    Data:
    konferencja 10-13.11
    Status:
    Published
  6. Subcellular localization of TMEM116 depends on its alternative splicing - impact on clear cell renal cell carcinoma etiology
    Authors:
    A. Kajdasz, N. Pstrąg,D. Niewiadomska, H.A.R. Bluyssen, J. Wesoly
    Conference:
    Transmembrane Proteins in Health and Disease (rok: 2018, ), Wydawca: Canadian Society for Molecular Biosciences
    Data:
    konferencja 11-15.04
    Status:
    Published
  7. Subcellular localization of ccRCC biomarker candidates- TMEM72 and TMEM207 and the role of microRNAs in their regulation
    Authors:
    N. Pstrąg, A. Kajdasz, D. Niewiadomska, H.A.R.Bluyssen, J. Wesoly
    Conference:
    Transmambrane proteins in Health and Disease (rok: 2018, ), Wydawca: Canadian Society for Molecular Biosciences
    Data:
    konferencja 11-15.04
    Status:
    Published