Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular mechanism of selected nitrophenol action in the ovary of hen (Gallus domesticus)

2014/15/B/NZ9/01986

Keywords:

4-nitrophenol 3-methyl-4-nitrophenol ovary chicken

Descriptors:

  • NZ9_2: Animal production
  • NZ9_13: Other related subjects

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Andrzej Sechman 

Number of co-investigators in the project: 5

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 563 470 PLN

Project start date (Y-m-d): 2015-07-17

Project end date (Y-m-d): 2019-07-16

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Homogenizator (7 500 PLN)
  2. Jednokanałowy spektrofotometr mikropłytkowy (BioTek Instruments) (57 000 PLN)
  3. Kołyska laboratoryjna MR-12 (3 800 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (13)
  • Book publications / chapters in book publications (1)
  1. Nitrophenols suppress steroidogenesis in prehierarchical chicken ovarian follicles by targeting STAR, HSD3B1 and CYP19A1, and downregulating LH and estrogen receptor expression
    Authors:
    Sechman A, Grzegorzewska AK, Grzesiak M, Kozubek A, Katarzyńska-Banasik D, Kowalik K, Hrabia A. K., Hrabia A.
    Academic press:
    Domestic Animal Endocrinology (rok: 2020, tom: 70, strony: 106378), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.domaniend.2019.07.006 - link to the publication
  2. In vitro effects of PNP and PNMC on apoptosis and proliferation in the hen ovarian stroma and prehierarchal follicles
    Authors:
    Grzegorzewska A.K., Hrabia A., Kowalik K., Katarzyńska-Banasik D., Kozubek A., Sechman A.
    Academic press:
    Acta Histochemica (rok: 2020, tom: 122, strony: 151463), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.acthis.2019.151463 - link to the publication
  3. Nitrophenols are negative modulators of steroidogenesis in preovulatory follicles of the hen (Gallus domesticus) ovary: An in vitro and in vivo study
    Authors:
    Kozubek A., Katarzyńska-Banasik D., Grzegorzewska A.K., Kowalik K., Hrabia A., Sechman A.
    Academic press:
    Theriogenology (rok: 2020, tom: 157, strony: 162-175), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2020.07.029 - link to the publication
  1. Effect of 4-nitrophenol (PNP) and 3-methyl-4-nitrophenol (PNMC) on mRNA expression and activity of selected caspases in white and yellowish ovarian follicles of the chicken
    Authors:
    Grzegorzewska A.K., Hrabia A., Grzesiak M., Karpeta A., Katarzyńska-Banasik D., Kowalik K., Mika M., Sechman A.
    Conference:
    XLVI ESNA Annual Meeting (rok: 2017, ), Wydawca: Publishing House of the University of Agriculture in Krakow
    Data:
    konferencja 29th August – 1st September
    Status:
    Published
  2. Effects of 4-nitrophenol and 3-methyl-4-nitrophenol on plasma LH and steroid hormone concentrations in the hen (Gallus domesticis)
    Authors:
    69.Sechman A., Grzegorzewska A.K., Mika M., Kozubek A., Karzyńska-Banasik D. Kowalik K., Hrabia, A.
    Conference:
    Poultry Days (rok: 2018, ), Wydawca: Mendel University in Brno
    Data:
    konferencja June 21-22, 2018
    Status:
    Published
  3. Effects of nitrophenol exposure on chicken ovarian steroidogenesis
    Authors:
    Sechman A.
    Conference:
    XXVII International Symposium Molecular and Physiological Aspects of Regulatory Processes in the Organism (rok: 2019, ), Wydawca: Jagiellonian University
    Data:
    konferencja 45577
    Status:
    Published
  4. The effect of nitrophenols on granulosa cell proliferation in chicken ovary
    Authors:
    Karpeta A., Katarzyńska D., Grzesiak M., Mika M., Sechman A.
    Conference:
    XVIII International Poultry Science Symposium PB WPSA Science to Practice – Practice to Science" (rok: 2016, ), Wydawca: WPSA
    Data:
    konferencja 14-16.09.2016
    Status:
    Published
  5. Effect of 4-nitrophenol (PNP) and 3-methyl-4-nitrophenol (PNMC) on caspase -3 and caspase-8 mRNA expression in chocken ovarian follicles.
    Authors:
    Grzegorzewska A.K., Grzesiak M., Hrabia A., Karpeta A., Katarzyńska-Banasik D., Kowalik K., Mika M., Sechman A
    Conference:
    International Conference "Biotechnology an Welfare in Animal Sciences in conjunction with the Session Perspectives for Cattle Breeding and Production" (rok: 2017, ), Wydawca: UR Kraków
    Data:
    konferencja 22-23 czerwca 2017
    Status:
    Published
  6. Effect of 4-nitrophenol and 3-methyl-4-nitrophenol on sex steroid secretion by ovarian follicles of the hen (Gallus domesticus)
    Authors:
    Sechman A., Grzesiak M., Karpeta A., Katarzyńska D., Hrabia A.
    Conference:
    45th Conference of European Society for New Methods in Agricultural Research (rok: 2016, ), Wydawca: Univeristy of Belgrade
    Data:
    konferencja 6-8 September 2016
    Status:
    Published
  7. Effects of nitrophenol administration on chicken ovarian steroidogenesis.
    Authors:
    72.Sechman A., Grzegorzewska A.K., Grzesiak M., Kozubek A., Karzyńska-Banasik D. Kowalik K., Hrabia, A.
    Conference:
    47th Conference of ESNA - European Society for New Methods in Agricultural Research (rok: 2018, ), Wydawca: University of Craiova, Faculty of Agronomy
    Data:
    konferencja 27-29 September, 2018
    Status:
    Published
  8. Nitrophenols affect steroid hormone secretion by chicken ovarian follicles.
    Authors:
    Sechman A., Grzesiak M., Karpeta A., KatarzyńskaD., Hrabia A.
    Conference:
    11th International Symposium on Avian Endocrinilogy (ISAE 2016) (rok: 2016, ), Wydawca: Gregory Bedecarrats, ISAE 2016
    Data:
    konferencja 11-14 October 2016
    Status:
    Published
  9. In vitro effect of 4-nitrophenol and 3-methyl-4-nitrophenol on STAR, HSD3B and CYP19A1 mRNA expression in the chicken preovulatory follicles
    Authors:
    Sechman A., Grzegorzewska A.K., Grzesiak M., Karpeta A., Katarzyńska-Banasik D., Wojnar T., Hrabia A.
    Conference:
    XLVI ESNA Annual Meeting (rok: 2017, ), Wydawca: Publishing House of the University of Agriculture in Krakow
    Data:
    konferencja 29th August – 1st September
    Status:
    Published
  10. Adverse effects of nitrophenols in the chicken ovary are associated with mRNA expression of LH and estrogen receptors; in vivo study
    Authors:
    78.Sechman A., Grzegorzewska A.K., Katarzyńska-Banasik D., Kowalik K., Kozubek A., Hrabia A.
    Conference:
    Risk Factors of Food Chain, XXth International Scientific Conference (rok: 2019, ), Wydawca: Slovak University of Agriculture
    Data:
    konferencja 9-11 września
    Status:
    Published
  11. Effect of 4-nitrophenol (PNP) and 3-methyl-4-nitrophenol (PNMC) on mRNA expression of estrogen receptors in chicken ovarian follicles
    Authors:
    68.Grzegorzewska A.K., Grzesiak M., Hrabia A., Kozubek A., Katarzyńska-Banasik D., Kowalik K., Mika M., Sechman A.
    Conference:
    International Conference "Biotechnology an Welfare in Animal Sciences" (rok: 2018, ), Wydawca: Ur Kraków
    Data:
    konferencja 19 czerwca 2018
    Status:
    Published
  12. Effect of nitrophenols on steroidogenesis in prehierarchical ovarian follicles of the hen (Gallus domesticus).
    Authors:
    Sechman A., Grzegorzewska A.K., Grzesiak M., Karpeta A., Katarzyńska-Banasik D., Kowalik K., Hrabia A.
    Conference:
    VIII Zjazd Towarzystwa Biologii Rozrodu (rok: 2017, ), Wydawca: Towarzystwo Biologii Rozrodu Olsztyn
    Data:
    konferencja 7-9 września 2017r
    Status:
    Published
  13. Nitrophenols affect expression and activity of caspases in white and yellowish follicles of the hen (Gallus domesticus) ovary
    Authors:
    71.Sechman A., Grzegorzewska A.K, Kozubek A., Katarzyńska-Banasik D., Kowalik K., Wojnar T., Hrabia A.
    Conference:
    XIX. International Conference "Risk Factors of Food Chain 2018" (rok: 2018, ), Wydawca: Szent Istvan University, Godollo, Hungary
    Data:
    konferencja 26-28 September 2018
    Status:
    Published
  1. Nitrophenols affect expression and activity of caspases in white and yellowish follicles of the hen (Gallus domesticus) ovary
    Authors:
    Sechman A, Grzegorzewska A.K., Kozubek A., Katarzyńska-Banasik D., Kowalik K., Wojnar T., Hrabia A.
    Book:
    Researched Risk Factors of Food Chain 2018 (rok: 2018, tom: brak, strony: 27-30), Wydawca: HOF Foundation
    Status:
    Published