Biodegradable poly(N-vinylpyrrolidone) hydrogels containing trehalose as bioprotective protein carriers

2014/15/N/ST8/02707

Keywords

Descriptors

  • ST8_8: Inżynieria materiałowa (biomateriały, metale, ceramika, polimery, kompozyty)
  • ST8_13: Inne zagadnienia pokrewne

Panel

ST8 – Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution

Politechnika Śląska, Wydział Chemiczny

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Małgorzata Anna Burek

Number of co-investigators in the project: 3

Call

PRELUDIUM 8 – announced on 2014-09-15

Amount awarded
149 400 PLN
Project start date
2015-09-03
Project end date
2018-12-02
Project duration
39 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Czytnik mikropłytek. Cost: 30 000 PLN

Information in the final report

Publication in academic press/journals (6)

  1. Study on protein release from hydrolytically degradable hydrogels governed by substituent effects in trehalose-based crosslinker and network properties

    Authors:
    Małgorzata Burek, Klaudia Kubic, Izabela Nabiałczyk, Sylwia Waśkiewicz, Ilona Wandzik
    Academic press:
    European Polymer Journal (year: 2019, volume: 111, pages: 123-133), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.eurpolymj.2018.12.020 – link to the publication
  2. Trehalose-rich, degradable hydrogels designed for trehalose release under physiologically relevant conditions

    Authors:
    Małgorzata Burek, Ilona Wandzik
    Academic press:
    Polymers (year: 2019, volume: 11, pages: 2027), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/polym11122027 – link to the publication
  3. Thermoresponsive microgels containing trehalose as soft matrices for 3D cell culture

    Authors:
    Małgorzata Burek, Sylwia Waśkiewicz, Anna Lalik, Sebastian Student, Tadeusz Bieg, Ilona Wandzik
    Academic press:
    Biomaterials Science (year: 2017, volume: 5, pages: 234-246), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c6bm00624h – link to the publication
  4. Synthetic Hydrogels with Covalently Incorporated Saccharides Studied for Biomedical Applications – 15 Year Overview

    Authors:
    Małgorzata Burek, Ilona Wandzik
    Academic press:
    Polymer Reviews (year: 2018, volume: 58, pages: 537-386), Publisher: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/15583724.2018.1443122 – link to the publication
  5. Thermoresponsive hydrogels with covalently incorporated trehalose as protein carriers

    Authors:
    Małgorzata Bureka, Sylwia Waśkiewicz, Stefan Awietjan, Ilona Wandzik
    Academic press:
    Reactive and Functional Polymers (year: 2017, volume: 119, pages: 105-115), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.reactfunctpolym.2017.08.009 – link to the publication
  6. Hydrogels with novel hydrolytically labile trehalose-based crosslinks: small changes – big differences in degradation behavior

    Authors:
    Małgorzata Burek, Sylwia Waśkiewicz, Anna Lalik, Ilona Wandzik
    Academic press:
    Polymer Chemistry (year: 2018, volume: 9, pages: 3721-3726), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c8py00488a – link to the publication

Book publications / chapters in book publications (1)

  1. HYDROŻELE ZAWIERAJĄCE JEDNOSTKI CUKROWE JAKO POTENCJALNE NOŚNIKI LEKÓW

    Authors:
    Małgorzata Burek, Ilona Wandzik, Sylwia Waśkiewicz
    Book:
    NA POGRANICZU CHEMII I BIOLOGII (year: 2015, volume: XXXV, pages: 107-117), Publisher: WYDAWNICTWO NAUKOWE UAM
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski