Role of heme oxygenase-1 in monocyte- and macophage-mediated progression of ischemic heart disease
2014/14/E/NZ1/00139
Keywords
Descriptors
- NZ1_1: Biologia molekularna
- NZ1_2: Biochemia
- NZ1_9: Biotechnologia
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
Voivodeship: małopolskie
Principal investigator (from the host institution)
dr hab. Agnieszka Anna Jaźwa-Kusior
Number of co-investigators in the project: 3
Call
SONATA BIS 4 – announced on 2014-06-16
- Amount awarded
- 1 865 000 PLN
- Project start date
- 2015-05-05
- Project end date
- 2021-03-04
- Project duration
- 70 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Aparat do pomiarów mikrokrążenia za pomocą analizy kontrastu obrazu spekli laserowych. Cost: 269 900 PLN
Information in the final report
Publication in academic press/journals (5)
-
Variability in Cardiac miRNA-122 Level Determines Therapeutic Potential of miRNA-Regulated AAV Vectors
- Authors:
- Izabela Kraszewska, Mateusz Tomczyk, Kalina Andrysiak, Monika Biniecka, Anne Geisler, Henry Fechner, Michał Zembala, Jacek Stępniewski, Józef Dulak, Agnieszka Jaźwa-Kusior
- Academic press:
- Molecular Therapy - Methods & Clinical Development (year: 2020, volume: 17, pages: 1190-1201), Publisher: Cell Press
- Status:
- Published
- DOI:
- 10.1016/j.omtm.2020.05.006 – link to the publication
-
Modulation of the monocyte/macrophage system in heart failure by targeting heme oxygenase-1.
- Authors:
- Mateusz Tomczyk, Izabela Kraszewska, Jozef Dulak, Agnieszka Jazwa-Kusior
- Academic press:
- Vascular Pharmacology (year: 2019, volume: 112, pages: 79-90), Publisher: Elsevier Inc.
- Status:
- Published
- DOI:
- 10.1016/j.vph.2018.08.011 – link to the publication
-
Characterization of hepatic macrophages and evaluation of inflammatory response in heme oxygenase-1 deficient mice exposed to scAAV9 vectors
- Authors:
- Mateusz Tomczyk, Izabela Kraszewska, Robert Mąka, Agnieszka Waligórska, Józef Dulak J, Agnieszka Jaźwa-Kusior
- Academic press:
- PLoS One (year: 2020, volume: 15, pages: e0240691), Publisher: Public Library of Science
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0240691 – link to the publication
-
Limb ischemia and vessel regeneration: Is there a role for VEGF?
- Authors:
- Agnieszka Jazwa, Urszula Florczyk, Anna Grochot-Przeczek, Bart Krist, Agnieszka Loboda, Alicja Jozkowicz, Jozef Dulak
- Academic press:
- Vascular Pharmacology (year: 2016, volume: 86, pages: 18-30), Publisher: Elsevier Inc.
- Status:
- Published
- DOI:
- 10.1016/j.vph.2016.09.003 – link to the publication
-
Splenic Ly6Chi monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice.
- Authors:
- Mateusz Tomczyk, Izabela Kraszewska, Krzysztof Szade, Karolina Bukowska-Strakova, Marco Meloni, Alicja Jozkowicz, Jozef Dulak, Agnieszka Jazwa
- Academic press:
- Basic Research in Cardiology (year: 2017, volume: 112, pages: 39), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s00395-017-0629-y – link to the publication
Articles in post-conference publications (2)
-
Cardiac repair after myocardial infarction - role of macrophages and heme oxygenase-1
- Authors:
- Tomczyk M, Kraszewska I, Kachamakova-Trojanowska N, Szade K, Dulak J, Jazwa-Kusior A
- Conference:
- The 44th FEBS Congress (year: 2019, pages: 65–431), Publisher: FEBS Open Bio/ Wiley
- Date:
- conference 6-11 lipca 2019
- Status:
- Published
- DOI:
- link to the publication
-
miRNA-regulated restriction of transgene expression to the heart is limited by interindividual variability in cardiac miRNA-122 level
- Authors:
- Kraszewska I, Tomczyk M, Biniecka M, Zembala M, Dulak J, Jazwa-Kusior A
- Conference:
- The 44th FEBS Congress (year: 2019, pages: 65–431), Publisher: FEBS Open Bio/ Wiley
- Date:
- conference 6-11 lipca 2019
- Status:
- Published
- DOI:
- link to the publication