Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Application of hyphenated and combined separation techniques in metabolomic studies and searching for cancer markers

2014/14/A/ST4/00641

Keywords:

cancer biomarkers xenoestrogens and their metabolites extraction techniques new generation of stationary phases in-vitro studies separation techniques mass spectrometry

Descriptors:

  • ST4_6: Instrumental methods in chemistry
  • ST5_6: Porous materials, ceramics, glasses
  • NZ5_5: Diagnostics in human diseases

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Mikołaja Kopernika, Wydział Chemii

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Bogusław Buszewski 

Number of co-investigators in the project: 6

Call: MAESTRO 6 - announced on 2014-06-16

Amount awarded: 2 399 950 PLN

Project start date (Y-m-d): 2015-05-15

Project end date (Y-m-d): 2018-05-14

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Fotobioreaktor (250 000 PLN)
  2. Homogenizator (40 000 PLN)
  3. Mikroskop optyczny.
  4. Autoklaw.
  5. Przesiewacz laboratoryjny, z sitami oraz uchwytami mocującymi (40 000 PLN)
  6. Ekstraktor SPE z pompką membranową i nakładką do azotu oraz zakup eksploatacyjnych elementów do ekstrakcji (60 000 PLN)
  7. Fluorymetr.
  8. Kruszarka szczękowa (45 000 PLN)
  9. Liofilizator (65 000 PLN)

Information in the final report

  • Publication in academic press/journals (14)
  1. Electrochemistry-mass spectrometry for in-vitro determination of selected chemotherapeutics and their electrochemical products in comparison to in-vivo approach
    Authors:
    M. Szultka-Młyńska, B. Buszewski
    Academic press:
    Talanta (rok: 2016, tom: 160, strony: 694-709), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.talanta.2016.07.054 - link to the publication
  2. Hypercrosslinked cholesterol-based polystyrene monolithic capillary columns
    Authors:
    D. Grzywiński, M. Szumski, B. Buszewski
    Academic press:
    Journal of Chromatorgrapy A (rok: 2016, tom: 1477, strony: 45617), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2016.11.023 - link to the publication
  3. Isolation, separation and preconcentration of biologically active compounds from plant matrices by extraction techniques
    Authors:
    V. Raks, H. Al-Suod, B. Buszewski
    Academic press:
    Chromatographia (rok: 2018, tom: 81, strony: 1889-202), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10337-017-3405-0 - link to the publication
  4. Mass spectrometric techniques for the analysis of volatile organic compounds emitted from bacteria
    Authors:
    I.-A. Ratiu, T. Ligor, V. BocosBintintan, B. Buszewski
    Academic press:
    Bioanalysis (rok: 2017, tom: 9(14), strony: 1069-1092), Wydawca: Future Science
    Status:
    Published
    DOI:
    10.4155/bio-2017-0051 - link to the publication
  5. Chromatographic behavior of selected antibiotic drugs supported by quantitative structure-retention relationships
    Authors:
    M. Szultka-Młyńska, B. Buszewski
    Academic press:
    Journal of Chromatography A (rok: 2016, tom: 1478, strony: 50-59), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2016.11.057 - link to the publication
  6. A study of zearalenone biosorption and metabolisation by prokaryotic and eukaryotic cells
    Authors:
    A. Rogowska, P. Pomastowski, K. Rafińska, V. Railean-Plugaru, M. Złoch, J. Walczak, B. Buszewski
    Academic press:
    Toxicon (rok: 2019, tom: 169, strony: 81-90), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.toxicon.2019.09.008 - link to the publication
  7. Study of in-vitro metabolizm of selected antibiotic drugs in human liver microsomes by liquid chromatography coupled with tandem mass spectrometry
    Authors:
    M. Szultka-Młyńska, B. Buszewski
    Academic press:
    Analytical & Bioanalytical Chemistry (rok: 2016, tom: 408, strony: 8273-8287), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s000216-016-9929-6 - link to the publication
  8. The determination of zearalenon and its major metabolitem in endometrial cancer tissues
    Authors:
    M. Pajewska, M. Łojko, K. Cendrowski, W. Sawicki, T. Kowalkowski, B. Buszewski, R. Gadzała-Kopciuch
    Academic press:
    Analytical & Bioanalytical Chemistry (rok: 2018, tom: 410, strony: 1571-1582), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-017-0807-7 - link to the publication
  9. Microbiology neutralization of zearalenon Rusing Lactococcus lactis and Bifidobacterium sp.
    Authors:
    A. Król, P. Pomastowski, K. Rafińska, V. Railean-Plugaru, J. Walczak, B. Buszewski
    Academic press:
    Analytical & Bioanalytical Chemistry (rok: 2018, tom: 410, strony: 943-952), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-017-0555-8 - link to the publication
  10. Non-target analysis of phospholipid and sphingolipid species in egg yolk using liquid chromatography/triple quadrupole tandem mass spectrometry
    Authors:
    B. Buszewski, J. Walczak, P. Zuvela, JJ.Liu
    Academic press:
    Journal of Chromatography A (rok: 2017, tom: 1487, strony: 179-186), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2017.01.055 - link to the publication
  11. Towards a new approach for the description of cyclo–2,4- dihydroxybenzoate, a substance which effectively mimics zearalenone in imprinted polymers designed for analyzing selected mycotoxins in urine
    Authors:
    R. Gadzała-Kopciuch, K. Kwaśniewska, A. Ludwiczak, P. Skrzyniarz, R. Jakubowski, W. Nowak, A. Wojtczak, B. Buszewski
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: nd), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20071588 - link to the publication
  12. Analytical techniques in lipidomics: state of art
    Authors:
    K. Jurowski, K. Kochan, J. Walczak, M. Barańska, W. Piekoszewski, B. Buszewski
    Academic press:
    Critical Review in Analytical Chemistry (rok: 2017, tom: 47(5), strony: 418-437), Wydawca: Taylor & Francis Online
    Status:
    Published
    DOI:
    10.1080/10408347.2017.1310613 - link to the publication
  13. Lactococcus lactis as a safe and inexpensive source of bioactive silver composites
    Authors:
    V. Railean-Plugaru, P. Pomastowski, K. Meller, M. Zloch, K. Rafińska, B. Buszewski
    Academic press:
    Applied Microbiology and Biotechnology (rok: 2017, tom: 101, strony: 1069-1092), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00253-017-8443-x - link to the publication
  14. Nanoporous conducting polimer-based coatings in microextraction techniques for environmental and biomedical applications
    Authors:
    M. Szultka-Młyńska, P. Olszowy, B. Buszewski
    Academic press:
    Critical REviews in Analytical Chemistry (rok: 2016, tom: 46(3), strony: 236-247), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/10408347.2015.1081051 - link to the publication

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