Application of hyphenated and combined separation techniques in metabolomic studies and searching for cancer markers

2014/14/A/ST4/00641

Keywords

Descriptors

  • ST4_6: Chemia analityczna
  • ST5_6: Materiały porowate
  • NZ5_5: Diagnostyka chorób człowieka

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Voivodeship: kujawsko-pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Bogusław Andrzej Buszewski

Number of co-investigators in the project: 6

Call

MAESTRO 6 – announced on 2014-06-16

Amount awarded
2 399 950 PLN
Project start date
2015-05-15
Project end date
2018-05-14
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Autoklaw.
  2. Ekstraktor SPE z pompką membranową i nakładką do azotu oraz zakup eksploatacyjnych elementów do ekstrakcji. Cost: 60 000 PLN
  3. Fluorymetr.
  4. Fotobioreaktor. Cost: 250 000 PLN
  5. Homogenizator. Cost: 40 000 PLN
  6. Kruszarka szczękowa. Cost: 45 000 PLN
  7. Liofilizator. Cost: 65 000 PLN
  8. Mikroskop optyczny.
  9. Przesiewacz laboratoryjny, z sitami oraz uchwytami mocującymi. Cost: 40 000 PLN

Information in the final report

Publication in academic press/journals (14)

  1. Non-target analysis of phospholipid and sphingolipid species in egg yolk using liquid chromatography/triple quadrupole tandem mass spectrometry

    Authors:
    B. Buszewski, J. Walczak, P. Zuvela, JJ.Liu
    Academic press:
    Journal of Chromatography A (year: 2017, volume: 1487, pages: 179-186), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2017.01.055 – link to the publication
  2. Hypercrosslinked cholesterol-based polystyrene monolithic capillary columns

    Authors:
    D. Grzywiński, M. Szumski, B. Buszewski
    Academic press:
    Journal of Chromatorgrapy A (year: 2016, volume: 1477, pages: 46347), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2016.11.023 – link to the publication
  3. Mass spectrometric techniques for the analysis of volatile organic compounds emitted from bacteria

    Authors:
    I.-A. Ratiu, T. Ligor, V. BocosBintintan, B. Buszewski
    Academic press:
    Bioanalysis (year: 2017, volume: 9(14), pages: 1069-1092), Publisher: Future Science
    Status:
    Published
    DOI:
    10.4155/bio-2017-0051 – link to the publication
  4. Isolation, separation and preconcentration of biologically active compounds from plant matrices by extraction techniques

    Authors:
    V. Raks, H. Al-Suod, B. Buszewski
    Academic press:
    Chromatographia (year: 2018, volume: 81, pages: 1889-202), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s10337-017-3405-0 – link to the publication
  5. Analytical techniques in lipidomics: state of art

    Authors:
    K. Jurowski, K. Kochan, J. Walczak, M. Barańska, W. Piekoszewski, B. Buszewski
    Academic press:
    Critical Review in Analytical Chemistry (year: 2017, volume: 47(5), pages: 418-437), Publisher: Taylor & Francis Online
    Status:
    Published
    DOI:
    10.1080/10408347.2017.1310613 – link to the publication
  6. Lactococcus lactis as a safe and inexpensive source of bioactive silver composites

    Authors:
    V. Railean-Plugaru, P. Pomastowski, K. Meller, M. Zloch, K. Rafińska, B. Buszewski
    Academic press:
    Applied Microbiology and Biotechnology (year: 2017, volume: 101, pages: 1069-1092), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00253-017-8443-x – link to the publication
  7. Study of in-vitro metabolizm of selected antibiotic drugs in human liver microsomes by liquid chromatography coupled with tandem mass spectrometry

    Authors:
    M. Szultka-Młyńska, B. Buszewski
    Academic press:
    Analytical & Bioanalytical Chemistry (year: 2016, volume: 408, pages: 8273-8287), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s000216-016-9929-6 – link to the publication
  8. Chromatographic behavior of selected antibiotic drugs supported by quantitative structure-retention relationships

    Authors:
    M. Szultka-Młyńska, B. Buszewski
    Academic press:
    Journal of Chromatography A (year: 2016, volume: 1478, pages: 50-59), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2016.11.057 – link to the publication
  9. Towards a new approach for the description of cyclo–2,4- dihydroxybenzoate, a substance which effectively mimics zearalenone in imprinted polymers designed for analyzing selected mycotoxins in urine

    Authors:
    R. Gadzała-Kopciuch, K. Kwaśniewska, A. Ludwiczak, P. Skrzyniarz, R. Jakubowski, W. Nowak, A. Wojtczak, B. Buszewski
    Academic press:
    International Journal of Molecular Sciences (year: 2019, volume: 20, pages: nd), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20071588 – link to the publication
  10. A study of zearalenone biosorption and metabolisation by prokaryotic and eukaryotic cells

    Authors:
    A. Rogowska, P. Pomastowski, K. Rafińska, V. Railean-Plugaru, M. Złoch, J. Walczak, B. Buszewski
    Academic press:
    Toxicon (year: 2019, volume: 169, pages: 81-90), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.toxicon.2019.09.008 – link to the publication
  11. Nanoporous conducting polimer-based coatings in microextraction techniques for environmental and biomedical applications

    Authors:
    M. Szultka-Młyńska, P. Olszowy, B. Buszewski
    Academic press:
    Critical REviews in Analytical Chemistry (year: 2016, volume: 46(3), pages: 236-247), Publisher: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/10408347.2015.1081051 – link to the publication
  12. Electrochemistry-mass spectrometry for in-vitro determination of selected chemotherapeutics and their electrochemical products in comparison to in-vivo approach

    Authors:
    M. Szultka-Młyńska, B. Buszewski
    Academic press:
    Talanta (year: 2016, volume: 160, pages: 694-709), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.talanta.2016.07.054 – link to the publication
  13. Microbiology neutralization of zearalenon Rusing Lactococcus lactis and Bifidobacterium sp.

    Authors:
    A. Król, P. Pomastowski, K. Rafińska, V. Railean-Plugaru, J. Walczak, B. Buszewski
    Academic press:
    Analytical & Bioanalytical Chemistry (year: 2018, volume: 410, pages: 943-952), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-017-0555-8 – link to the publication
  14. The determination of zearalenon and its major metabolitem in endometrial cancer tissues

    Authors:
    M. Pajewska, M. Łojko, K. Cendrowski, W. Sawicki, T. Kowalkowski, B. Buszewski, R. Gadzała-Kopciuch
    Academic press:
    Analytical & Bioanalytical Chemistry (year: 2018, volume: 410, pages: 1571-1582), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00216-017-0807-7 – link to the publication

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Graphic design and implementation: Jakub Piotrowski