Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Studies on the biological activity of selected aminomethylidenebisphosphonic acids

2014/13/B/NZ4/01105

Keywords:

bisphophonates breast cancers chemotherapy adjuvant anticancer therapy tumor metastases osteoporosis

Descriptors:

  • NZ4_12: Other related subjects
  • NZ5_7: Human disease treatment
  • ST5_16:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Nasulewicz-Goldeman 

Number of co-investigators in the project: 5

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 421 650 PLN

Project start date (Y-m-d): 2015-02-11

Project end date (Y-m-d): 2019-02-10

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Biological effects of aromatic bis[aminomethylidenebis(phosphonic)] acids in osteoclast precursors in vitro
    Authors:
    Anna Nasulewicz-Goldeman, Waldemar Goldeman, Ewa Mrówczyńska, Joanna Wietrzyk
    Academic press:
    Chemical Biology and Drug Design (rok: 2019, tom: 94, strony: 1835-1848), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/cbdd.13597 - link to the publication
  2. "Antimetastatic activity of aromatic aminomethylidenebisphosphonates in 4T1 mouse breast cancer model"
    Authors:
    Anna Nasulewicz-Goldeman, Waldemar Goldeman, Diana Papiernik, Marcin Nowak, Ewa Mrówczyńska, Joanna Wietrzyk
    Academic press:
    International Journal of Oncology , Wydawca: Spandidos Publications
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Aromatic bis[aminomethylidenebis(phosphonic)] acids prevent ovariectomy-induced bone loss and suppress osteoclastogenesis in mice
    Authors:
    Anna Nasulewicz-Goldeman, Waldemar Goldeman, Anna Nikodem, Marcin Nowak, Diana Papiernik, Tomasz M. Goszczyński, Joanna Wietrzyk
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 9590-9607), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22179590 - link to the publication
  1. A new bisphosphonate - naphthyl-1,5-diaminobis(methylidenebisphosphonic) acid shows a direct biological effect on MDA-MB-231 human breast carcinoma cells
    Authors:
    Anna Nasulewicz-Goldeman, Waldemar Goldeman, Ewa Zielińska, Joanna Wietrzyk
    Conference:
    15th St. Gallen International Breast Cancer Conference (rok: 2017, ), Wydawca: Elsevier
    Data:
    konferencja 15-18 marca 2017
    Status:
    Published
    DOI:
    link to the publication
  2. Biological activity of benzene-1,4-bis[aminomethylidene (bisphosphonic)] acid towards J774E macrophages – a model of osteoclasts.
    Authors:
    Nasulewicz-Goldeman A, Goldeman W, Wietrzyk J:
    Conference:
    The Tenth Multidisciplinary Conference on Drug Research, Korytnica (rok: 2016, ), Wydawca: Instytut Farmaceutyczny w Warszawie
    Data:
    konferencja 15-19.05.2016
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy