Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Cytoprotective role of antioxidants towards cells of myogenic origin in in vitro and in situ conditions

2014/13/B/NZ3/04646

Keywords:

myogenic progenitor cells antioxidants cell aging

Descriptors:

  • NZ3_8: Stem cell biology
  • NZ3_4: Ageing

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Kurpisz 

Number of co-investigators in the project: 11

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 1 115 875 PLN

Project start date (Y-m-d): 2015-02-18

Project end date (Y-m-d): 2018-08-17

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (2)
  • Book publications / chapters in book publications (2)
  1. Human myoblast transplantation in mice infarcted heart alters the expression profile of cardiac genes associated with left ventricle remodeling.
    Authors:
    Wiernicki B, Rozwadowska N, Malcher A, Kolanowski T, Zimna A, Rugowska A, Kurpisz M.
    Academic press:
    Int J Cardiol. (rok: 2016, tom: 202, strony: 710-721), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijcard.2015.09.115 - link to the publication
  2. In vitro culture of primary human myoblasts by using the dextran microcarriers Cytodex3®.
    Authors:
    Rozwadowska N, Malcher A, Baumann E, Kolanowski TJ, Rucinski M, Miętkiewski T, Fiedorowicz K, Kurpisz M.
    Academic press:
    Folia Histochem Cytobiol. (rok: 2016, tom: 52(2), strony: 81-90), Wydawca: Polish Scientific Publishers and Polish Histochemical and Cytochemical Society at VM Media
    Status:
    Published
  3. Transient and Stable Overexpression of Extracellular Superoxide Dismutase is Positively Associated with the Myogenic Function of Human Skeletal Muscle-Derived Stem/Progenitor Cells
    Authors:
    Magdalena Nowaczyk, Agnieszka Malcher, Agnieszka Zimna, Wojciech Łabędź, Łukasz Kubaszewski , Katarzyna Fiedorowicz , Kamil Wierzbiński , Natalia Rozwadowska, Maciej Kurpisz
    Academic press:
    Antioxidants (rok: 2020, tom: 9, strony: 817), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox9090817 - link to the publication
  4. Addition of Popular Exogenous Antioxidant Agent, PBN, to Culture Media May Be an Important Step to Optimization of Myogenic Stem/Progenitor Cell Preparation Protocol
    Authors:
    Magdalena Nowaczyk, Agnieszka Malcher, Agnieszka Zimna , Wojciech Łabędź, Łukasz Kubaszewski, Wojciech Barczak, Błażej Rubiś, Natalia Rozwadowska and Maciej Kurpisz
    Academic press:
    Antioxidants (rok: 2021, tom: 10, strony: 959), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox10060959 - link to the publication
  5. Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies.
    Authors:
    Zimna A, Kurpisz M.
    Academic press:
    Biomed Res Int 2015;2015:549412 (pp.1-13). (rok: 2015, tom: 2015, strony: 549412), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2015/549412 - link to the publication
  1. Potential use of superparamagnetic iron oxide nanoparticles for bioimaging of myoblasts in post-infarction heart stem cells therapy.
    Authors:
    Kamil R. Wierzbiński, Tomasz Szymański, Natalia Rozwadowska1, Jakub D. Rybka2,3, Agnieszka Zimna1, Karolina Nowicka-Bauer, Agnieszka Malcher, Magdalena Przybył, Michael Giersig, Maciej Kurpisz
    Conference:
    XXI Sympozjum Sekcji Kardiologii Eksperymentalnej Polskiego Towarzystwa Kardiologicznego (rok: 2016, ), Wydawca: Via Medica sp. z o.o., Gdańsk
    Data:
    konferencja 13-15 października, Rynia
    Status:
    Published
  2. Cytoprotection role of antioxidants towards human myogenic cells of tissue reservoir.
    Authors:
    Magdalena Przybył, Agnieszka Malcher, Agnieszka Zimna, Kamil R. Wierzbiński1, Karolina Nowicka- Bauer1, Wojciech Łabędź, Łukasz Kubaszewski, Jacek Kaczmarczyk,Natalia Rozwadowska, Maciej Kurpisz
    Conference:
    Sympozjum Sekcji Kardiologii Eksperymentalnej Polskiego Towarzystwa Kardiologicznego (rok: 2016, ), Wydawca: Via Medica sp. z o.o., Gdańsk
    Data:
    konferencja 13-15 października, Rynia
    Status:
    Published
  1. Biological bases of cardiac function and the pro-regenerative potential of stem cells in the treatment of myocardial disorder.
    Authors:
    Bednarowicz KA, Kurpisz M.
    Book:
    Cardiac cell culture technologies. Microfluidic and on-chip systems. (rok: 2017, ), Wydawca: Springer International Publishing
    Status:
    Published
  2. Myocardial infarction
    Authors:
    Rozwadowska N, Kurpisz M.
    Book:
    A Roadmap to Mesaenchymal Stem Cell-based Therapeutics: From the bench to the Clinic (rok: 2018, ), Wydawca: Academic Press
    Status:
    Published