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Information on the principal investigator and host institution

Information of the project and the call

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Mechanisms of extracellular export of small non-coding RNA in autoimmune demyelination in multiple sclerosis.

2014/13/N/NZ6/03510

Keywords:

multiple sclerosis autoimmune demyelination microRNA next generation sequencing exosomes

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ6_8: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny w Łodzi, Katedra Neurologii

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Igor Selmaj 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2015-03-25

Project end date (Y-m-d): 2018-03-24

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (6)
  1. Multiple sclerosis: Serum-derived exosomes express myelin proteins.
    Authors:
    Galazka G, Mycko MP, Selmaj I, Raine CS, Selmaj KW.
    Academic press:
    Multiple Sclerosis (rok: 2017, tom: 135245851769659, strony: 45301), Wydawca: Sage
    Status:
    Published
    DOI:
    10.1177/1352458517696597 - link to the publication
  2. The role of exosomes in CNS inflammation and their involvement in multiple sclerosis
    Authors:
    Selmaj I, Mycko MP, Raine CS, Selmaj KW.
    Academic press:
    J neuroimmunology (rok: 2017, tom: 306, strony: 45301), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jneuroim.2017.02.002 - link to the publication
  3. Global exosome transcriptome profiling reveals biomarkers for multiple sclerosis
    Authors:
    Selmaj I, Cichalewska M, Namiecinska M, Galazka G, Horzelski W, Selmaj KW, Mycko MP
    Academic press:
    Ann Neurol (rok: 2017, tom: 81, strony: 703-717), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ana.24931 - link to the publication
  1. Serum exosomal microRNA profiling reveals new biomarkers of MS
    Authors:
    Igor Selmaj, Magdalena Namiecińska, Maria Cichalewska, Hanna Ćwiklińska, CS Raine, Krzysztof Selmaj, Marcin P. Mycko
    Conference:
    European Academy of Neurology (rok: 2016, ), Wydawca: European Journal of Neurology
    Data:
    konferencja June
    Status:
    Published
  2. Circulating exosomes analysis reveals different microRNA composition in relapsing-remitting multiple sclerosis patients
    Authors:
    I. Selmaj, M. Cichalewska, M. Namiecinska, K. Selmaj, M. Mycko
    Conference:
    European Academy of Neurology (rok: 2017, ), Wydawca: European Journal of Neurology
    Data:
    konferencja June
    Status:
    Published
  3. Serum exosomes microRNA-122-5p, miRNA-196b-5p, miRNA-301a-3p and miRNA-532-5p represent a biomarkers of multiple sclerosis
    Authors:
    I. Selmaj, M. Namiecinska, M. Cichalewska, G. Galazka, M.P. Mycko, K.W. Selmaj
    Conference:
    ECTRIMS (rok: 2017, ), Wydawca: Multiple Sclerosis Journal
    Data:
    konferencja October
    Status:
    Published
  4. Exosomal RNA sequences as biomarkers of MS
    Authors:
    Igor Selmaj, Krzysztof Selmaj, Magdalena Mariasiewicz, Marcin P Mycko
    Conference:
    European Academy of Neurology (rok: 2015, ), Wydawca: European Journal of Neurology
    Data:
    konferencja June
    Status:
    Published
  5. Exosomal RNA signature in multiple sclerosis patients
    Authors:
    Igor Selmaj, Magdalena Mariasiewicz, Krzysztof Selmaj, Marcin P Mycko
    Conference:
    ECTRIMS (rok: 2015, ), Wydawca: Multiple Sclerosis Journal
    Data:
    konferencja 7-10 OCT
    Status:
    Published
  6. Serum exosomes as biomarkers of multiple sclerosis
    Authors:
    Igor Selmaj, Magdalena Namiecińska, Maria Cichalewska, Grazyna Gałązka, Krzysztof Selmaj
    Conference:
    ECTRIMS 2016 (rok: 2016, ), Wydawca: Multiple Sclerosis Journal
    Data:
    konferencja 14-17 sep
    Status:
    Published
    DOI:
    link to the publication

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