Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Participation of the TET enzymes in aging of human skin

2014/13/B/NZ4/00157

Keywords:

aging skin epigenetics 5-hydroxymethylation TET enzymes

Descriptors:

  • NZ4_12: Other related subjects
  • NZ3_4: Ageing

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Monika Puzianowska-Kuźnicka 

Number of co-investigators in the project: 5

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 964 370 PLN

Project start date (Y-m-d): 2015-01-23

Project end date (Y-m-d): 2018-11-22

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Alterations in the genomic distribution of 5hmC in in vivo aged human skin fibroblasts
    Authors:
    Kolodziej-Wojnar P, Borkowska J, Wicik Z, Domaszewska-Szostek A, Polosak J, Cakala-Jakimowicz M, Bujanowska O, Puzianowska-Kuznicka M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 22, strony: 78), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22010078 - link to the publication
  2. Alterations in 5hmC level and genomic distribution in aging-related epigenetic drift in human adipose stem cells
    Authors:
    Borkowska J, Domaszewska-Szostek A, Kołodziej P, Wicik Z, Połoska J, Buyanovskaya O, Charzewski L, Stańczyk M, Noszczyk B, Puzianowska-Kuznicka M.
    Academic press:
    Epigenomics (rok: 2020, tom: 12, strony: 423-437), Wydawca: Future Medicine
    Status:
    Published
    DOI:
    10.2217/epi-2019-0131 - link to the publication