Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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An examination of the impact of saponins on Langmuir monolayers as model lipid membranes.

2014/13/N/ST4/04122

Keywords:

Model cell membranes Langmuir monolayers Saponins Anti-bacterial hemolytic anti-fungal as well as cytotoxic activity

Descriptors:

  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST4_1: Physical chemistry, chemical physics
  • ST4_5: Analytical chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Warszawska, Wydział Chemiczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marta Orczyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 124 880 PLN

Project start date (Y-m-d): 2015-02-25

Project end date (Y-m-d): 2017-08-24

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Sensor potencjału powierzchniowego (37 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. The influence of steroidal and triterpenoid saponins on monolayer models of the outer leaflets of human erythrocytes, E.coli and S. cerevisiae cell membranes
    Authors:
    Marta Orczyk ; Kamil Wojciechowski; Gerald Brezesinski
    Academic press:
    The Journal of Physical Chemistry B , Wydawca: ACS Publications
    Status:
    Submitted
  2. Disordering Effects of Digitonin on Phospholipid Monolayers
    Authors:
    Marta Orczyk, Kamil Wojciechowski, Gerald Brezesinski
    Academic press:
    Langmuir (rok: 2017, tom: 33, strony: 3871-3881), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.langmuir.6b04613 - link to the publication