Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structural changes of the alveolar membrane induced by lipid peroxidation and atmospheric pollutants: theoretical and experimental model studies

2014/13/B/ST4/04995

Keywords:

molecular modeling force fields Langmuir monolayers phospholipids lung surfactant

Descriptors:

  • ST4_15: Colloid chemistry
  • ST4_5: Analytical chemistry
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Korchowiec 

Number of co-investigators in the project: 5

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 452 640 PLN

Project start date (Y-m-d): 2015-02-04

Project end date (Y-m-d): 2018-04-03

Project duration:: 38 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Moduł topograficzny 3D z niezbędnym wyposażeniem (150 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. The impact of lipid oxidation on the functioning of a lung surfactant model
    Authors:
    A. Stachowicz-Kussnierz, L. Cwiklik, J. Korchowiec, E. Rogalska and B. Korchowiec
    Academic press:
    Physical Chemistry Chemical Physics (rok: 2018, tom: 20, strony: 24968-24978), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c8cp04496a - link to the publication
  2. The role of DPPG in lung surfactant exposed to benzo[a]pyrene
    Authors:
    Beata Korchowiec, Anna Stachowicz-Kuśnierz and Jacek Korchowiec
    Academic press:
    Environmental Science Processes & Impacts (rok: 2019, tom: 21, strony: 438-445), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c8em00497h - link to the publication
  3. Mixed DPPC/POPC Monolayers: All-atom Molecular Dynamics Simulations and Langmuir Monolayer Experiments
    Authors:
    A. Olżyńska, M. Zubek, M. Roeselova, J. Korchowiec, L. Cwiklik
    Academic press:
    Biochimica et Biophysica Acta (rok: 2016, tom: 1858, strony: 3120–3130), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2016.09.015 - link to the publication
  4. Modeling Lung Surfactant Interactions with Benzo[a]pyrene
    Authors:
    A. Stachowicz-Kuśnierz, S. Trojan, L. Cwiklik, B. Korchowiec, J. Korchowiec
    Academic press:
    Chemistry - A European Journal (rok: 2017, tom: 23, strony: 5307-5316), Wydawca: Willey
    Status:
    Published
    DOI:
    10.1002/chem.201605945 - link to the publication