Structural changes of the alveolar membrane induced by lipid peroxidation and atmospheric pollutants: theoretical and experimental model studies

2014/13/B/ST4/04995

Keywords

Descriptors

  • ST4_15: Chemia teoretyczna i obliczeniowa
  • ST4_5: Chemia i fizykochemia powierzchni
  • ST4_13: Chemia fizyczna układów biologicznych

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Jagielloński, Wydział Chemii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Jacek Grzegorz Korchowiec

Number of co-investigators in the project: 5

Call

OPUS 7 – announced on 2014-03-17

Amount awarded
452 640 PLN
Project start date
2015-02-04
Project end date
2018-04-03
Project duration
38 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Moduł topograficzny 3D z niezbędnym wyposażeniem. Cost: 150 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. Mixed DPPC/POPC Monolayers: All-atom Molecular Dynamics Simulations and Langmuir Monolayer Experiments

    Authors:
    A. Olżyńska, M. Zubek, M. Roeselova, J. Korchowiec, L. Cwiklik
    Academic press:
    Biochimica et Biophysica Acta (year: 2016, volume: 1858, pages: 3120–3130), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2016.09.015 – link to the publication
  2. The role of DPPG in lung surfactant exposed to benzo[a]pyrene

    Authors:
    Beata Korchowiec, Anna Stachowicz-Kuśnierz and Jacek Korchowiec
    Academic press:
    Environmental Science Processes & Impacts (year: 2019, volume: 21, pages: 438-445), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c8em00497h – link to the publication
  3. The impact of lipid oxidation on the functioning of a lung surfactant model

    Authors:
    A. Stachowicz-Kussnierz, L. Cwiklik, J. Korchowiec, E. Rogalska and B. Korchowiec
    Academic press:
    Physical Chemistry Chemical Physics (year: 2018, volume: 20, pages: 24968-24978), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c8cp04496a – link to the publication
  4. Modeling Lung Surfactant Interactions with Benzo[a]pyrene

    Authors:
    A. Stachowicz-Kuśnierz, S. Trojan, L. Cwiklik, B. Korchowiec, J. Korchowiec
    Academic press:
    Chemistry - A European Journal (year: 2017, volume: 23, pages: 5307-5316), Publisher: Willey
    Status:
    Published
    DOI:
    10.1002/chem.201605945 – link to the publication

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Graphic design and implementation: Jakub Piotrowski