Understanding the interactions of zinc with zincophores and zinc transporters in fungal pathogens
2014/13/D/ST5/02868
Keywords
Descriptors
- ST5_14: Chemia koordynacyjna
- ST5_16: Chemia biologiczna
- ST5_24: Chemia nieorganiczna
Panel
ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution
Uniwersytet Wrocławski, Wydział Chemii
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
SONATA 7 – announced on 2014-03-17
- Amount awarded
- 448 620 PLN
- Project start date
- 2015-02-12
- Project end date
- 2018-09-11
- Project duration
- 43 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- potencjometr. Cost: 140 000 PLN
- spektrofotometr UV-Vis.
Information in the final report
Publication in academic press/journals (14)
-
Zinc homeostasis at the bacteria/host interface—from coordination chemistry to nutritional immunity.
- Authors:
- Wątły J., Potocki S., Rowińska-Żyrek M.
- Academic press:
- Chemistry-A European Journal (year: 2016, volume: 22, pages: 15992-16010), Publisher: Wiley
- Status:
- Published
- DOI:
- 10.1002/chem.201602376 – link to the publication
-
'Coordination of Zn2+ and Cu2+ to the membrane disrupting fragment of amylin
- Authors:
- Rowińska-Żyrek M.
- Academic press:
- Dalton Transactions (year: 2016, volume: 45, pages: 8099-8106), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/c6dt00628k – link to the publication
-
Fungal zinc homeostasis - a tug of war between the pathogen and host
- Authors:
- Walencik Paulina K., Wątły Joanna, Rowińska-Żyrek Magdalena
- Academic press:
- Current Medicinal Chemistry (year: 2016, volume: 23, pages: 3717-3729), Publisher: Bentham Science Publishers
- Status:
- Published
- DOI:
- 10.2174/0929867323666160817163834 – link to the publication
-
Zn(II) - pramlintide : stability, binding sites and unexpected aggregation
- Authors:
- Łoboda D., Rowińska-Żyrek M.
- Academic press:
- Journal of Inorganic Biochemistry (year: 2017, volume: 174, pages: 150-155), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jinorgbio.2017.06.008 – link to the publication
-
Zinc binding site in Pra1, a zincophore from Candida albicans
- Authors:
- Łoboda D., Rowińska-Żyrek M.
- Academic press:
- Dalton Transactions (year: 2017, volume: 46, pages: 13695-13703), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/c7dt01675a – link to the publication
-
Impact of histidine spacing on modified polyhistidine tag : metal ion interactions
- Authors:
- Wątły J., Hecel A., Rowińska-Żyrek M., Kozłowski H.
- Academic press:
- Inorganica Chimica Acta (year: 2018, volume: 472, pages: 119-126), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.ica.2017.06.053 – link to the publication
-
Ag + complexes as potential therapeutic agents in medicine and pharmacy
- Authors:
- Hecel A., Kolkowska P., Krzywoszynska K., Szebesczyk A., Rowinska-Zyrek M., Kozlowski H.
- Academic press:
- Current Medicinal Chemistry (year: 2019, volume: 26(4), pages: 624-647), Publisher: Bentham Science Publishers
- Status:
- Published
- DOI:
- 10.2174/0929867324666170920125943 – link to the publication
-
Poly-Xaa Sequences in Proteins – Biological Role and Interactions with Metal Ions. Chemical and Medical Aspects
- Authors:
- Wątły J., Hecel A., Kołkowska P., Kozłowski H., Rowińska-Żyrek M.
- Academic press:
- Current Medicinal Chemistry (year: 2018, volume: 25, pages: 22-48), Publisher: Bentham Science Publishers
- Status:
- Published
-
Investigation on the metal binding sites of a putative Zn(II) transporter in opportunistic yeast species Candida albicans
- Authors:
- Belotti D., Łoboda D., Rowińska-Żyrek M., Remelli M.
- Academic press:
- New Journal of Chemistry (year: 2018, volume: 42, pages: 8123-8130), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/C8NJ00533H – link to the publication
-
Histidine tracts in human transcription factors: insight into metal ion coordination ability
- Authors:
- Hecel A., Wątły J., Rowińska-Żyrek M., Świątek-Kozłowska J., Kozłowski H.
- Academic press:
- Journal of Biological Inorganic Chemistry (year: 2018, volume: 23, pages: 81-90), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1007/s00775-017-1512-x – link to the publication
-
Periplasmic HupE region-Ni2+ interactions: Thermodynamics, binding mode and competition with Cu2+ and Zn2+
- Authors:
- Rowińska-Żyrek, M.
- Academic press:
- Inorganica Chimica Acta (year: 2017, volume: 460, pages: 141-147), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.ica.2016.08.007 – link to the publication
-
Candida albicans zincophore and zinc transporter interactions with Zn(II) and Ni(II)
- Authors:
- Łoboda D., Rowińska-Żyrek M.
- Academic press:
- Dalton Transactions (year: 2018, volume: 47, pages: 2646-2654), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/c7dt04403h – link to the publication
-
HENRYK — An endless source of metal coordination surprises
- Authors:
- Kołkowska P., Hecel A., Kędzierska D., Ostrowska M., Walencik P., Wątły J., Zdyb K., Spodzieja M., Rodziewicz-Motowidło S., Potocki S., Łuczkowski M., Gumienna-Kontecka E., Rowińska-Żyrek M.
- Academic press:
- Journal of Inorganic Biochemistry (year: 2016, volume: 163, pages: 258-265), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jinorgbio.2016.02.030 – link to the publication
-
Metal interactions with the transmembrane region of HupE Ni2+ transporter explain its efficiency
- Authors:
- Rowińska-Żyrek M.
- Academic press:
- Journal of Inorganic Biochemistry (year: 2018, volume: 180, pages: 33-38), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jinorgbio.2017.11.026 – link to the publication
Book publications / chapters in book publications (2)
-
Nickel Binding Sites – Coordination Modes and Thermodynamics
- Authors:
- Rowińska-Żyrek M., Kozłowski H.
- Book:
- The biological inorganic chemistry of nickel (year: 2017, volume: 1, pages: 43-59), Publisher: Royal Society of Chemistry
- Status:
- Published
-
The role of trace elements in living organisms
- Authors:
- Gumienna-Kontecka E., Rowińska-Żyrek M., Łuczkowski M.
- Book:
- Recent advances in trace elements (year: 2018, volume: 1, pages: 177-206), Publisher: Wiley
- Status:
- Published