Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Applications of High Resolution Magic Angle Spinning Spectroscopy in research of selected anticancer drug embedded in mesoporous silica nanoparticles.

2014/13/N/ST5/03444

Keywords:

HR MAS drug delivery systems anticancer drug NMR spectroscopy

Descriptors:

  • ST5_1: Structural properties of materials
  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST5_6: Porous materials, ceramics, glasses

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Ewa Skorupska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 99 770 PLN

Project start date (Y-m-d): 2015-02-05

Project end date (Y-m-d): 2017-02-04

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. mieszadło magnetyczne z Heat-On Block System (5 610 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Thermal Solvent-Free Method of Loading of Pharmaceutical Cocrystals into the Pores of Silica Particles: A Case of Naproxen/ Picolinamide Cocrystal
    Authors:
    Ewa Skorupska, Agata Jeziorna, Marek J. Potrzebowski
    Academic press:
    Journal of Physical Chemistry C (rok: 2016, tom: 120, strony: 13169−13180), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpcc.6b05302 - link to the publication
  2. Chlorambucil labelled with the phenosafranin scaffold as a new chemotherapeutic for both imaging and cancer treatment
    Authors:
    Malgorrzata Sierant, Ewa Skorupska, Adam Michalski, Slawomir Kazmierski, Urszula Steinke, Pawel Uznanski
    Academic press:
    Colloids and Surfaces B: Biointerfaces (rok: 2017, tom: 159, strony: 820-828), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2017.08.045 - link to the publication
  3. Solid State NMR Characterization of Ibuprofen:Nicotinamide Cocrystals and New Idea for Controlling of Release of the Drugs Embedded into Mesoporous Silica Particles
    Authors:
    Ewa Skorupska, Slawomir Kazmierski, Marek J. Potrzebowski
    Academic press:
    Molecular Pharmaceutics (rok: 2017, tom: 14(5), strony: 1800-1810), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.molpharmaceut.7b00092 - link to the publication