Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Research for biomarkers of neuroplasticity in prelignually deaf children treated with cochlear implantation.

2014/13/D/NZ5/03337

Keywords:

neuroplasticity auditory system molecular regulation cochlear implantation

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ3_7: Signal transduction
  • NZ4_7: Neurophysiology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Fizjologii i Patologii Słuchu

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Monika Matusiak 

Number of co-investigators in the project: 4

Call: SONATA 7 - announced on 2014-03-17

Amount awarded: 354 400 PLN

Project start date (Y-m-d): 2015-03-05

Project end date (Y-m-d): 2020-09-04

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. drukarka (700 PLN)
  2. aparat do elektroforezy - Bio-rad, Protean 2 Xi (10 600 PLN)
  3. komputer laptop (3 500 PLN)
  4. tablet (2 300 PLN)
  5. dyski zewnętrzne (2 szt.) (1 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  • Book publications / chapters in book publications (2)
  1. Ocena wyników leczenia głuchoty prelingwalnej za pomocą wszczepienia implantu ślimakowego w świetle funkcjonaalnego poliorfizmu genów MMP-9 i BDNF
    Authors:
    Monika Matusiak, Dominika Oziębło, Monika Ołdak, Anita Obycka, Leszek Kaczmarek, Henryk Skarżyński
    Academic press:
    Nowa Audiofonologia (rok: 2021, tom: 10, strony: 45614), Wydawca: Instytut Narządów Zmysłów, ul. Mokra 1, Kajetany, 05-830 Nadarzyn
    Status:
    Published
  2. MMP-9 plasma level as biomarker of cochlear implantation outcome in cohort study of deaf children
    Authors:
    Monika Matusiak, Dominika Oziębło, Monika Ołdak, Emilia Rejmak, Dominik Dobek, Leszek Kaczmarek, Henryk Skarżynski
    Academic press:
    European Archives of Oto-Rhino-Larynology , Wydawca: Springer
    Status:
    Submitted
  3. Neuroplasticity after cochlear implantation as assessed by the plasma level of MMp-9 and its genetic polymorphisms: a prospctive study of congenitally deaf children
    Authors:
    Monika Matusiak, Dominika Oziębło, Monika Ołdak, Emilia Rejmak, Leszek Kaczmarek, Henryk Skarżyński,
    Academic press:
    Journal of Hearing Science (rok: 2022, tom: 12, strony: 47-53), Wydawca: Institute of Sensory Organs, 1 Mokra Street, Kajetany, 05-830 Nadarzyn
    Status:
    Published
    DOI:
    10.17430/JHS.2022.12.3.5 - link to the publication
  4. Functional polymorphism of MMP9 and BDNF as potential biomarker of auditory neuroplasticity in prelingual deafness treatment with cochlear implantation – a retrospective cohort analysis.
    Authors:
    Matusiak Monika, Oziębło Dominika, Obrycka Anita, Ołdak Monika, Kaczmarek Leszek, Skarżyński Piotr, Skarżyński Henryk
    Academic press:
    Trends in Hearing (rok: 2021, tom: 25, strony: 45304), Wydawca: SAGE JOURNALS
    Status:
    Published
    DOI:
    10.1177/23312165211002140 - link to the publication
  5. Longitudinal changes of BDNF and MMP-9 protein plasma levels in children after cochlear implantation
    Authors:
    Monika Matusiak, Dominika Oziębło, Monika Ołdak, Emilia Rejmak, Leszek Kaczmarek, Henryk Skarżyński
    Academic press:
    International Journal od Molecular Sciences (rok: 2023, tom: 24(4), strony: 3714), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24043714 - link to the publication
  6. Prospective cohort study reveals MMP-9, a neuroplasticity regulator, as a prediction marker of cochlear implantation outcome in prelingual deafness treatment.
    Authors:
    Monika Matusiak, Dominika Oziębło, Monika Ołdak, Emilia Rejmak, Leszek Kaczmarek, Piotr Skarżyński, Henryk Skarżyński
    Academic press:
    Molecular Neurobiology (rok: 2022, tom: 59, strony: 2190-2203), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-022-02732-7 - link to the publication
  1. Molekularny biomerker neuroplastyczności w leczeniu głuchoty wrodzonej za pomocą implantaxcji slimakowej - MMP-9?
    Authors:
    Monika Matusiak
    Conference:
    4. Kongres Zdrowie Polaków (rok: 2023, ), Wydawca: Instytut Fizjologii i Patologii Słuchu
    Data:
    konferencja 17-18 10 2022
    Status:
    Published
  1. Genetic biomarkers of neuroplasticity in the treatment of children with prelingual deafness with cochlear implantation
    Authors:
    Monika Matusiak Henryk Skarżyński
    Book:
    Methods of Partial Deafness Treatment (rok: 2022, tom: 1, strony: 31-35), Wydawca: Francis and Taylor
    Status:
    Published
  2. Genetyczne biomarkery neuroplastyczności w leczeniu głuchoty prelingwalnej za pomocą wszczepienia implantu ślimakowego
    Authors:
    Monika Matusiak Henryk Skarżyński
    Book:
    Implanty słuchowe. Wskaznia i wyniki. Na podstawie międzynarodowych warsztatów otochirurgicznych "Window Approach Workshops". (rok: 2021, tom: 1, strony: 101-106), Wydawca: Instytut Fizjologii i Patologii Słuchu w Warszawie
    Status:
    Published