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Impact of triclosan on mouse cortical neurons

2014/13/N/NZ4/04809

Keywords:

triclosan apoptosis AhR NMDA CYP1A1 CYP1B1

Descriptors:

  • NZ4_8: Neuroendocrinology
  • NZ4_7: Neurophysiology
  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Konrad Szychowski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2015-02-12

Project end date (Y-m-d): 2017-02-11

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Triclosan activates aryl hydrocarbon receptor (AhR)-dependent apoptosis and affects Cyp1a1 and Cyp1b1 expression in mouse neocortical neurons
    Authors:
    Szychowski K.A., Wnuk A., Kajta M., Wójtowicz A.K
    Academic press:
    Environmental Research (rok: 2016, tom: 151, strony: 106-114), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.envres.2016.07.019 - link to the publication
  2. Triclosan-Evoked Neurotoxicity Involves NMDAR Subunits with the Specific Role of GluN2A in Caspase-3-Dependent Apoptosis
    Authors:
    Konrad A. Szychowski, Agnieszka Wnuk, Joanna Rzemieniec, Małgorzata Kajta, Teresa Leszczyńska, Anna K. Wójtowicz
    Academic press:
    Molecular Neurobiology (rok: 2019, tom: 56, strony: 45303), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-018-1083-z - link to the publication
  1. Impact of triclosan on apoptotic processes in neuronal cells
    Authors:
    Szychowski K.A. Sitarz A.M., Wojtowicz A.K
    Conference:
    XIX International Congress of the Polish Pharmacological Society (rok: 2015, ), Wydawca: Elsevier: Pharmacological Reports
    Data:
    konferencja 17-19 Wrzesień
    Status:
    Published
  2. Impact of triclosan on cytochrome CYP1A1 and CYP1B1 expression and activity in mouse neocortical neurons
    Authors:
    Szychowski K.A, Sitarz A.M., Wnuk A., Kajta M., Wojtowicz A.K.
    Conference:
    Neuropsychoimmunological mechanisms in the pathology of neurodegenerative diseases. From biomarkers to therapeutics (rok: 2015, ), Wydawca: Instytut Medycyny Doświadczalnej i Klinicznej PAN w Warszawie
    Data:
    konferencja 22-23 Września
    Status:
    Published
  3. Impact of triclosan on expression of NMDA receptor subunits in mouse neocortical neurons.
    Authors:
    Szychowski K.A., Wnuk A, Binduga U, Kajta M, Wójtowicz A.K.
    Conference:
    The 13th International Symposium "Molecular basis of pathology and therapy in neurological disorders" and The 4th International Conference "Stem cells: therapeutic outlook for nervous system disorders" (rok: 2016, ), Wydawca: Termedia Publishing House
    Data:
    konferencja 17-18 listopada
    Status:
    Published

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