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Poszukiwanie inhibitorów oddziaływania białek MDM2-p53. Trójpodstawione pochodne 1,5-dihydro-2H-pirol-2-onu.

2014/12/T/ST5/00684

Keywords:

Descriptors:

  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Ewa Wrona 

Number of co-investigators in the project: 2

Call: ETIUDA 2 - announced on 2013-12-16

Amount awarded: 69 845 PLN

Project start date (Y-m-d): 2014-10-01

Project end date (Y-m-d): 2015-04-30

Project duration:: 7 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  1. A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-furanone-Based Antagonists of the p53-Mdm2 Interaction
    Authors:
    Ewa Wrona, Aleksandra Twarda, Krzysztof M. Zak, Bogdan Musielak, Marcin D. Tomala, Przemyslaw Grudnik, Dobrosława Krzemień, Mateusz Jablonski, Justyna Kalinowska-Tluscik, Alexander Dömling, Grzegorz Dubin, and Tad A. Holak
    Academic press:
    Angewandte Chemie International Edition , Wydawca: John Wiley & Sons, Inc.
    Status:
    Submitted
    DOI:
    brak - link to the publication

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