Wpływ benzylopiperazyny - modelowego związku z grupy dopalaczy na stan energetyczny komórek, apoptozę i stres oksydacyjny

2014/12/T/NZ7/00262

Descriptors

  • NZ7_15: Toksykologia
  • NZ3_3: Apoptoza

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Jagielloński, Wydział Chemii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Karolina Persona

Number of co-investigators in the project: 2

Call

ETIUDA 2 – announced on 2013-12-16

Amount awarded
57 288 PLN
Project start date
2014-10-01
Project end date
2015-03-31
Project duration
6 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (2)

  1. An In Vitro Study of the Neurotoxic Effects of N-Benzylpiperazine: A Designer Drug of Abuse

    Authors:
    Karolina Persona, Anna Polus, Joanna Góralska, Anna Gruca, Aldona Dembińska-Kieć, Wojciech Piekoszewski
    Academic press:
    Neurotoxicity Research (year: 2016, volume: brak, pages: 46033), Publisher: Springer US
    Status:
    Published
    DOI:
    10.1007/s12640-016-9604-x – link to the publication
  2. Analytical methodologies for the determination of benzodiazepines in biological samples

    Authors:
    Karolina Persona, Katarzyna Madej, Paweł Knihnicki, Wojciech Piekoszewski
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (year: 2015, volume: 113, pages: 239-264), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2015.02.017 – link to the publication

Articles in post-conference publications (1)

  1. Mitochondria dysfunction and oxidative stress in neurodegenerative process influenced by the designer drug of abuse - N-benzylpiperazine

    Authors:
    Karolina Persona, Anna Polus, Joanna Góralska, Anna Gruca, Aldona Dembińska-Kieć, Wojciech Piekoszewski
    Conference:
    12th International Symposium, Molecular Basis of Pathology and Therapy in Neurological Disorders (year: 2014, pages: 351-352), Publisher: FOLIA NEUROPATHOLOGICA
    Date:
    conference 20 - 21 listopada 2014
    Status:
    Published
    DOI:
    link to the publication

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Graphic design and implementation: Jakub Piotrowski