Endogenny układ opioidowy i nocyceptynowy jako potencjalne cele farmakologiczne dla terapeutyków działających w układzie pokarmowym
2014/12/T/NZ7/00252
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
- NZ5_7: Leczenie chorób człowieka
- NZ5_3: Patogeneza chorób człowieka
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Medyczny w Łodzi, Wydział Lekarski
Voivodeship: łódzkie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
ETIUDA 2 – announced on 2013-12-16
- Amount awarded
- 95 214 PLN
- Project start date
- 2014-10-01
- Project end date
- 2015-09-30
- Project duration
- 12 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (6)
-
The role of MOP and DOP receptors in treatment of diarrhea-predominant irritable bowel syndrome.
- Authors:
- Jarmuż A, Zielińska M, Banaszek M, Leń K, Storr M, Fichna J
- Academic press:
- Mini Reviews in Medicinal Chemistry (year: 2016, volume: 18 (16), pages: 1462-69), Publisher: Bentham Science
- Status:
- Published
- DOI:
- 10.2174/1389557516666160804165318 – link to the publication
-
Anti-inflammatory effect of dual nociceptin and opioid receptor agonist, BU08070, in experimental colitis in mice
- Authors:
- Zielińska, M.; Ben Haddou, T.; Cami-Kobeci, G.; Sałaga, M.; Jarmuż, A.; Padysz, M.; Kordek, R.; Spetea, M.; Husbands, SM.; Fichna J.
- Academic press:
- European Journal of Pharmacology (year: 2015, volume: 765, pages: 582-590), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.ejphar.2015.09.021 – link to the publication
-
Methyl-orvinol—Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome
- Authors:
- Zielińska M, Jarmuż A, Wasilewski A, Cami-Kobeci G, Husbands S, Fichna J
- Academic press:
- Pharmacological Reports (year: 2017, volume: 69, pages: 350-357), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.pharep.2016.12.001 – link to the publication
-
Tenapanor hydrochloride for the treatment of constipation-predominant irritable bowel syndrome
- Authors:
- Zielińska, M.; Wasilewski, A.; Fichna J.
- Academic press:
- Expert Opinion on Investigational Drugs (year: 2015, volume: 24(8), pages: 1093-1099), Publisher: Taylor&Francis Online
- Status:
- Published
- DOI:
- 10.1517/13543784.2015.1054480 – link to the publication
-
Melatonin, but not melatonin receptor agonists Neu-P11 and Neu-P67, attenuates TNBS-induced colitis in mice
- Authors:
- Zielińska, M.; Jarmuż, A.; Sałaga, M.; Kordek, R.; Laudon, M.; Storr, M.; Jakub Fichna J.
- Academic press:
- Naunyn-Schmiedeberg's Archives of Pharmacology (year: 2016, volume: 389, pages: 511-519), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1007/s00210-016-1214-x – link to the publication
-
Mixed MOP/DOP agonist biphalin elicits anti-transit effect in mouse models mimicking diarrhea-predominant irritable bowel syndrome symptoms
- Authors:
- Zielińska, M.; Jarmuż, A.; Sałaga, M.; Lipkowski, A.; Fichna J.
- Academic press:
- Pharmacological Reports (year: 2016, volume: 68, pages: 32-36), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.pharep.2015.06.001 – link to the publication
Book publications / chapters in book publications (2)
-
Patient's Guide in Colorectal Cancer: Prophylaxis, Diet and Lifestyle
- Authors:
- M Zielińska & Włodarczyk J
- Book:
- Introduction to Gastrointestinal Diseases Vol. 2 (year: 2017, volume: 2, pages: 155-166), Publisher: Elsevier
- Status:
- Published
-
Clinical Treatment in Colorectal Cancer: Other Aspects
- Authors:
- Jarmuż A & Zielińska M
- Book:
- Introduction to Gastrointestinal Diseases Vol. 2 (year: 2017, volume: 2, pages: 145-154), Publisher: Elsevier
- Status:
- Published