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Information on the principal investigator and host institution

Information of the project and the call

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Endogenny układ opioidowy i nocyceptynowy jako potencjalne cele farmakologiczne dla terapeutyków działających w układzie pokarmowym

2014/12/T/NZ7/00252

Keywords:

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ5_7: Human disease treatment
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marta Zielińska 

Number of co-investigators in the project: 2

Call: ETIUDA 2 - announced on 2013-12-16

Amount awarded: 95 214 PLN

Project start date (Y-m-d): 2014-10-01

Project end date (Y-m-d): 2015-09-30

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (6)
  • Book publications / chapters in book publications (2)
  1. Methyl-orvinol—Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome
    Authors:
    Zielińska M, Jarmuż A, Wasilewski A, Cami-Kobeci G, Husbands S, Fichna J
    Academic press:
    Pharmacological Reports (rok: 2017, tom: 69, strony: 350-357), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2016.12.001 - link to the publication
  2. Tenapanor hydrochloride for the treatment of constipation-predominant irritable bowel syndrome
    Authors:
    Zielińska, M.; Wasilewski, A.; Fichna J.
    Academic press:
    Expert Opinion on Investigational Drugs (rok: 2015, tom: 24(8), strony: 1093-1099), Wydawca: Taylor&Francis Online
    Status:
    Published
    DOI:
    10.1517/13543784.2015.1054480 - link to the publication
  3. Anti-inflammatory effect of dual nociceptin and opioid receptor agonist, BU08070, in experimental colitis in mice
    Authors:
    Zielińska, M.; Ben Haddou, T.; Cami-Kobeci, G.; Sałaga, M.; Jarmuż, A.; Padysz, M.; Kordek, R.; Spetea, M.; Husbands, SM.; Fichna J.
    Academic press:
    European Journal of Pharmacology (rok: 2015, tom: 765, strony: 582-590), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2015.09.021 - link to the publication
  4. Melatonin, but not melatonin receptor agonists Neu-P11 and Neu-P67, attenuates TNBS-induced colitis in mice
    Authors:
    Zielińska, M.; Jarmuż, A.; Sałaga, M.; Kordek, R.; Laudon, M.; Storr, M.; Jakub Fichna J.
    Academic press:
    Naunyn-Schmiedeberg's Archives of Pharmacology (rok: 2016, tom: 389, strony: 511-519), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1007/s00210-016-1214-x - link to the publication
  5. The role of MOP and DOP receptors in treatment of diarrhea-predominant irritable bowel syndrome.
    Authors:
    Jarmuż A, Zielińska M, Banaszek M, Leń K, Storr M, Fichna J
    Academic press:
    Mini Reviews in Medicinal Chemistry (rok: 2016, tom: 18 (16), strony: 1462-69), Wydawca: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1389557516666160804165318 - link to the publication
  6. Mixed MOP/DOP agonist biphalin elicits anti-transit effect in mouse models mimicking diarrhea-predominant irritable bowel syndrome symptoms
    Authors:
    Zielińska, M.; Jarmuż, A.; Sałaga, M.; Lipkowski, A.; Fichna J.
    Academic press:
    Pharmacological Reports (rok: 2016, tom: 68, strony: 32-36), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2015.06.001 - link to the publication
  1. Clinical Treatment in Colorectal Cancer: Other Aspects
    Authors:
    Jarmuż A & Zielińska M
    Book:
    Introduction to Gastrointestinal Diseases Vol. 2 (rok: 2017, tom: 2, strony: 145-154), Wydawca: Elsevier
    Status:
    Published
  2. Patient's Guide in Colorectal Cancer: Prophylaxis, Diet and Lifestyle
    Authors:
    M Zielińska & Włodarczyk J
    Book:
    Introduction to Gastrointestinal Diseases Vol. 2 (rok: 2017, tom: 2, strony: 155-166), Wydawca: Elsevier
    Status:
    Published

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