Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Adjusting the neurohormonal system of natural immunity and adaptive in children with primary hypertension

2013/11/B/NZ4/03832

Keywords:

primary hypertension children adjusting neurohormonal system,

Descriptors:

  • NZ4_11: Metabolism
  • NZ4_2: Physiology
  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut "Pomnik - Centrum Zdrowia Dziecka"

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Mieczysław Litwin 

Number of co-investigators in the project: 12

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 681 250 PLN

Project start date (Y-m-d): 2014-09-17

Project end date (Y-m-d): 2018-08-16

Project duration:: 47 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (10)
  1. Accelerated maturation of peripheral blood lymphocytes in children with primary hypertension
    Authors:
    Anna Niemirska, Jacek Michałkiewicz, Mieczysław Litwin
    Academic press:
    Postępy Nauk Medycznych (rok: 2015, tom: XXVIII, strony: 766-771), Wydawca: borgis
    Status:
    Published
  2. Expression of adiponectin receptors on peripheral blood leukocytes of hypertensive children is associated with the severity of hypertension.
    Authors:
    Lidia Gackowska; Mieczysław Litwin; Joanna Trojanek; Andrzej Eljaszewicz; Izabela Kubiszewska; Anna Niemirska; Aldona Wierzbicka; Jacek Michałkiewicz
    Academic press:
    BioMed Res.Int. (rok: 2015, tom: Vol.15, strony: Article ID 742646, 11 s.), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2015/742646 - link to the publication
  3. Loss of CD31receptor in CD4þ and CD8þ T-cell subsets in childrenwith primary hypertension is associated with hypertension severity and hypertensive target organ damage
    Authors:
    Lidia Gackowskaa, Jacek Michałkiewicza,b, Anna Niemirskac, Anna Helmin-Basaa, Maciej Kłosowskia, Izabela Kubiszewskaa, --Lukasz Obrycki, Mieczysław Szaleckid, Aldona Wierzbickae, Zbigniew Kułagaf, Malgorzata Wiesea, and Mieczysław Litw
    Academic press:
    Journal of Hypertension (rok: 2018, tom: 36, strony: 2148-2156), Wydawca: Wolters Kluwer Health
    Status:
    Published
    DOI:
    10.1097/HJH.0000000000001811 - link to the publication
  4. The role of immune system in pathogenesis of primary hypertension
    Authors:
    Jacek Michałkiewicz
    Academic press:
    Postępy Nauk Medycznych (rok: 2015, tom: XXVIII, strony: 779-786), Wydawca: Borgis
    Status:
    Published
  5. Vascular aging: lessons from pediatric hypertension.
    Authors:
    Mieczysław Litwin; Janusz Feber; Marcel Ruzicka
    Academic press:
    Canadian Journal of Cardiology (rok: 2016, tom: Vol. 32, Nr 5, strony: 642-649), Wydawca: ELSEVIER SCIENCE INC.
    Status:
    Published
    DOI:
    10.1016/j.cjca.2016.02.064 - link to the publication
  6. Altered matrix metalloproteinase 9 and tissue inhibitor of metalloproteinases 1 levels in children with primary hypertension.
    Authors:
    Anna Niemirska; Mieczysław Litwin; Joanna Trojanek; Lidia Gackowska; Izabela Kubiszewska; Aldona Wierzbicka; Zbigniew Kułaga; Jacek Michałkiewicz
    Academic press:
    Journal of Hypertension (rok: 2016, tom: Vol. 34, Nr 9, strony: 1815-1822), Wydawca: LIPPINCOTT WILLIAMS & WILKINS.
    Status:
    Published
    DOI:
  7. Assessment of central blood pressure as a predictor of target organ damage in children with primary hypertension
    Authors:
    Łukasz Obrycki, Jędrzej Sarnecki, Anna Niemirska, *Mieczysław Litwin
    Academic press:
    Łukasz Obrycki, Jędrzej Sarnecki, Anna Niemirska, *Mieczysław Litwin (rok: 2015, tom: XXVIII, strony: 766-771), Wydawca: Borgis
    Status:
    Published
  8. Central systolic blood pressure and central pulse pressure predict left ventricular hypertrophy in hypertensive children
    Authors:
    Mieczysław Litwin; Łukasz Obrycki; Anna Niemirska; Jędrzej Sarnecki; Zbigniew Kułaga
    Academic press:
    Pediatric Nephrplogy (rok: 2019, tom: Vol. 34, Nr 4, strony: 703 - 712), Wydawca: Spinger
    Status:
    Published
    DOI:
    10.1007/s00467-018-4136-7 - link to the publication
  9. Primary hypertension is a disease of premature vascular aging associated with neuro-immuno-metabolic abnormalities.
    Authors:
    Mieczysław Litwin; Janusz Feber; Anna Niemirska; Jacek Michałkiewicz
    Academic press:
    Pediatr.Nephrol. (rok: 2016, tom: Vol. 31, nr 2, strony: 185 - 194), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00467-015-3065-y - link to the publication
  10. Why should we screen for arterial hypertension in children and adolescents?
    Authors:
    Mieczysław Litwin
    Academic press:
    Pediatric Nephrology (rok: 2018, tom: Vol. 33 Nr 1, strony: 83-92), Wydawca: Spinger
    Status:
    Published
    DOI:
    10.1007/s00467-017-3739-8 - link to the publication