Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of cholinergic anti-inflammatory pathway in the preventing of negative effect of inflammation on the GnRH/LH secretion in the follicular phase ewes

2013/11/B/NZ9/01848

Keywords:

acetylocholine cholinergic antiinflammatory pathway GnRH LH hypothalamus anterior pituitary ewe

Descriptors:

  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Andrzej Herman 

Number of co-investigators in the project: 7

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 733 000 PLN

Project start date (Y-m-d): 2014-07-23

Project end date (Y-m-d): 2018-01-22

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator z wytrząsanie (37 800 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (5)
  1. Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide- Induced Systemic Inflammation
    Authors:
    Andrzej P. Herman, Dorota Tomaszewska-Zaremba, Marta Kowalewska, Aleksandra Szczepkowska, Małgorzata Oleszkiewicz, Agata Krawczyńska, Maciej Wójcik, Hanna Antushevich, Janina Skipor
    Academic press:
    Mediators of Inflammation (rok: 2018, tom: 2018, strony: Article ID 9150207,), Wydawca: HINDAWI LTD
    Status:
    Published
    DOI:
    10.1155/2018/9150207 - link to the publication
  2. Effect of central injection of neostigmine on the bacterial endotoxin induced suppression of GnRH/LH secretion in ewes during the follicular phase of the estrous cycle
    Authors:
    Andrzej P. Herman, Janina Skipor, Agata Krawczyńska, Joanna Bochenek, K. Wojtulewicz, Bartosz Pawlina, Hanna Antushevich, Anna Herman, Dorota Tomaszewska-Zaremba
    Academic press:
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (rok: 2019, tom: brak, strony: brak), Wydawca: MDPI
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Peripheral inhibitor of AChE, neostigmine, prevents the inflammatory dependent suppression of GnRH/LH secretion during the Follicular phase of the estrous cycle
    Authors:
    Herman A.P., Skipor J., Krawczyńska A., Bochenek J., Wojtulewicz K., Antushevich H., Herman A., Paczesna K., Romanowicz K., Tomaszewska-Zaremba D
    Academic press:
    BioMedResearch International (rok: 2017, tom: 2017, strony: 6823209), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2017/6823209 - link to the publication
  1. Effect of acetylcholinesterase blocking on mRNA expression of pattern recognition receptors, pro-inflammatory cytokines and their receptors in the ovine choroid plexus under basal and LPS-challenged conditions
    Authors:
    Kowalewska M., Szczepkowska A., Oleszkiewicz M., Herman A.P., Skipor J.
    Conference:
    19th International Symposium on Signal Transduction at the Blood-Brain Barriers (rok: 2016, ), Wydawca: University of Copenhagen
    Data:
    konferencja 14-16.09.2016
    Status:
    Published
  2. Effect of central injection of donepezil on the bacterial endotoxin induced suppression of GnRH/LH secretion in ewes during the follicular phase of the estrous cycle
    Authors:
    Herman AP, Skipor J, Król K, Bochenek J, Krawczyńska A, Antushevich A, Kopycińska K, Romanowicz K, Tomaszewska-Zaremba D
    Conference:
    VIII Zjazd Towarzystwa Biologii Rozrodu (rok: 2017, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 7-9 września 2017
    Status:
    Published
  3. Central injection of donepezil influences lipopolysaccharide-induced synthesis of pro-inflammatory cytokines and gene expression of their receptor in the hypothalamus of ewes
    Authors:
    Tomczyk M., Skipor J., Antushevich A., Krawczyńska A., Bochenek J., Wojtulewicz K., Tomaszewska-Zaremba D., Herman AP.
    Conference:
    XIVth International Conference of Young Researchers "Physiology and Biochemistry in Animal Nutrition (rok: 2017, ), Wydawca: Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN
    Data:
    konferencja 14–15 września2017
    Status:
    Published
  4. Donepezil reduces the LPS-induced suppression of GnRH synthesis in the hypothalamus of ewe during the follicular phase of the estrous cycle
    Authors:
    Herman A.P., Skipor J., Bochenek J., Kopycińska K., Król K., Antushevich H., Krawczyńska A., Tomaszewska – Zaremba D.
    Conference:
    The 4rd Winter Workshop of the Society for Biology of Reproduction Central and Local Regulations of Reproductive Processes" (rok: 2016, ), Wydawca: Oddział Krakowski Towarzystwa Biologii Rozrodu
    Data:
    konferencja 3-5.02.2016
    Status:
    Published
  5. The effect of Donepezil and Neostigmine on the gene expression of proinflammatory cytokines and their receptors in the preoptic area of follicular phase ewes during peripheral acute inflammation
    Authors:
    Krawczyńska A., Wójcik M., Kopycińska K., Skipor J., Bochenek J., Król K., Antushevich H., Tomaszewska-Zaremba D., Herman A.P.
    Conference:
    Physiology and Biochemistry in Animal Nutrition (rok: 2016, ), Wydawca: Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN
    Data:
    konferencja 27-28.09.2016
    Status:
    Published

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