Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The role of NADPH oxidase in the pathogenesis of perivascular adipose tissue inflammation in spontaneously hypertensive rats

2013/11/N/NZ4/00310

Keywords:

NADPH oxidase hypertension perivascular inflammation vascular dysfunction oxiddative stress

Descriptors:

  • NZ4_2: Physiology
  • NZ5_3: Pathogenesis of human diseases
  • NZ6_3: Animal immunology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Ryszard Nosalski 

Number of co-investigators in the project: 3

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 149 565 PLN

Project start date (Y-m-d): 2014-09-17

Project end date (Y-m-d): 2018-03-16

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Perivascular adipose tissue inflammation in vascular disease
    Authors:
    Nosalski R. Guzik T.J.
    Academic press:
    Br J Pharmacol. (rok: 2017, tom: 174(20), strony: 3496–3513), Wydawca: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1111/bph.13705 - link to the publication
  2. T-Cell-Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension
    Authors:
    Nosalski R, Siedlinski M, Denby L, McGinnigle E, Nowak M, Cat AND, Medina-Ruiz L, Cantini M, Skiba D, Wilk G, Osmenda G, Rodor J, Salmeron-Sanchez M, Graham G, Maffia P, Graham D, Baker AH, Guzik TJ.
    Academic press:
    Circ Res (rok: 2020, tom: 126, strony: 988–1003), Wydawca: LIPPINCOTT WILLIAMS & WILKINS
    Status:
    Published
    DOI:
    10.1161/CIRCRESAHA.119.315428 - link to the publication
  3. Novel Immune Mechanisms in Hypertension and Cardiovascular Risk
    Authors:
    Ryszard Nosalski, Eilidh McGinnigle, Mateusz Siedlinski, Tomasz J. Guzik
    Academic press:
    Current Cardiovascular Risk Reports (rok: 2017, tom: 11, strony: 12), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12170-017-0537-6 - link to the publication
  4. Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension
    Authors:
    Nosalski R, Mikolajczyk T, Siedlinski M, Saju B, Koziol J, Maffia P, Guzik TJ.
    Academic press:
    Pharmacol Res (rok: 2020, ), Wydawca: Elsevier
    Status:
    Accepted for publication
    DOI:
    10.1016/j.phrs.2020.105235 - link to the publication

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