Projects funded by the NCN
Analysis of factors determining clearance or persistence of infection with the hepatitis C virus (HCV) in the initial stage of infection: the role of molecular characteristics of the virus and the immune response.
2013/11/B/NZ6/01679
Keywords:
HCV initial stage of infection blood donors virus elimination NGS immune response.
Descriptors:
- NZ6_8: Other related subjects
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Warszawski Uniwersytet Medyczny, I Wydział Lekarski
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 7
Call: OPUS 6 - announced on 2013-09-16
Amount awarded: 770 900 PLN
Project start date (Y-m-d): 2014-08-26
Project end date (Y-m-d): 2019-08-25
Project duration:: 60 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- NanoDrop (35 000 PLN)
- Zamrażarka -80oC (30 000 PLN)
Information in the final report
- Publication in academic press/journals (5)
- Hepatitis C virus (HCV) genotype 1b displays higher genetic variability of hypervariable region 1 (HVR1) than genotype 3.Authors:Janiak M, Perlejewski K, Grabarczyk P, Kubicka-Russel D, Zagordi O, Berak H, Osuch S, Pawełczyk A, Bukowska-Ośko I, Płoski R, Laskus T, Caraballo Cortés K.Academic press:Sci Rep (rok: 2019, tom: Sep 6;9(1), strony: 12846), Wydawca: Nature Publishing GroupStatus:PublishedDOI:10.1038/s41598-019-49258-y. - link to the publication
- Next-generation Sequencing Analysis of New Genotypes Appearing During Antiviral Treatment of Chronic Hepatitis C Reveals that These Are Selected from Pre-existing Minor Strains.Authors:Bukowska-Ośko I, Perlejewski K, Caraballo Cortés K, Pollak A, Berak H, Pawełczyk A, Horban A, Kosińska J, Płoski R, Laskus T, Radkowski M.Academic press:J Gen Virol (rok: 2019, tom: 100(3), strony: 1633-1642), Wydawca: Microbiology Society JournalsStatus:PublishedDOI:10.1099/jgv.0.001225 - link to the publication
- Next-generation sequencing analysis of a cluster of hepatitis C virus infections in a haematology and oncology center.Authors:Caraballo Cortes K, Rosińska M, Janiak M, Stępień M, Zagordi O, Perlejewski K, Osuch S, Pawełczyk A, Bukowska-Ośko I, Płoski R, Grabarczyk P, Laskus T, Radkowski M.Academic press:PlosONE (rok: 2018, tom: Mar 22;13(3):, strony: e0194816.), Wydawca: PUBLIC LIBRARY SCIENCE.Status:PublishedDOI:10.1371/journal.pone.0194816. - link to the publication
- Next-Generation Sequencing of Hepatitis C Virus (HCV) Mixed-Genotype Infections in Anti-HCV-Negative Blood Donors.Authors:Janiak M, Caraballo Cortés K, Perlejewski K, Kubicka-Russel D, Grabarczyk P, Demkow U, Radkowski M.Academic press:Adv Exp Med Biol (rok: 2018, tom: 1096:., strony: 65-71), Wydawca: SPRINGER-VERLAG BERLIN.Status:PublishedDOI:10.1007/5584_2018_190. - link to the publication
- Seronegative hepatitis C virus (HCV) infection in Polish blood donors – virological characteristics of index donations and follow-up observationsAuthors:Piotr Grabarczyk, Dorota Kubicka-Russel, Aneta Kopacz, Grzegorz Liszewski, Ewa Sulkowska, Paulina Zwolińska, Kazimierz Madaliński, Maciej Marek, MałgorzataSzabelewska, Ewa Świątek, Tomasz Laskus, Marek RadkowskiAcademic press:J Med Virol (rok: 2020, tom: Mar;92(3), strony: 339-347), Wydawca: WILEYStatus:PublishedDOI:10.1002/jmv.25617 - link to the publication