Analysis of factors determining clearance or persistence of infection with the hepatitis C virus (HCV) in the initial stage of infection: the role of molecular characteristics of the virus and the immune response.
2013/11/B/NZ6/01679
Keywords
Descriptors
- NZ6_8: Inne zagadnienia pokrewne
Panel
NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution
Warszawski Uniwersytet Medyczny, I Wydział Lekarski
Voivodeship: mazowieckie
Principal investigator (from the host institution)
prof. Marek Mirosław Radkowski
Number of co-investigators in the project: 7
Call
OPUS 6 – announced on 2013-09-16
- Amount awarded
- 770 900 PLN
- Project start date
- 2014-08-26
- Project end date
- 2019-08-25
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- NanoDrop. Cost: 35 000 PLN
- Zamrażarka -80oC. Cost: 30 000 PLN
Information in the final report
Publication in academic press/journals (5)
-
Hepatitis C virus (HCV) genotype 1b displays higher genetic variability of hypervariable region 1 (HVR1) than genotype 3.
- Authors:
- Janiak M, Perlejewski K, Grabarczyk P, Kubicka-Russel D, Zagordi O, Berak H, Osuch S, Pawełczyk A, Bukowska-Ośko I, Płoski R, Laskus T, Caraballo Cortés K.
- Academic press:
- Sci Rep (year: 2019, volume: Sep 6;9(1), pages: 12846), Publisher: Nature Publishing Group
- Status:
- Published
- DOI:
- 10.1038/s41598-019-49258-y. – link to the publication
-
Seronegative hepatitis C virus (HCV) infection in Polish blood donors – virological characteristics of index donations and follow-up observations
- Authors:
- Piotr Grabarczyk, Dorota Kubicka-Russel, Aneta Kopacz, Grzegorz Liszewski, Ewa Sulkowska, Paulina Zwolińska, Kazimierz Madaliński, Maciej Marek, MałgorzataSzabelewska, Ewa Świątek, Tomasz Laskus, Marek Radkowski
- Academic press:
- J Med Virol (year: 2020, volume: Mar;92(3), pages: 339-347), Publisher: WILEY
- Status:
- Published
- DOI:
- 10.1002/jmv.25617 – link to the publication
-
Next-generation Sequencing Analysis of New Genotypes Appearing During Antiviral Treatment of Chronic Hepatitis C Reveals that These Are Selected from Pre-existing Minor Strains.
- Authors:
- Bukowska-Ośko I, Perlejewski K, Caraballo Cortés K, Pollak A, Berak H, Pawełczyk A, Horban A, Kosińska J, Płoski R, Laskus T, Radkowski M.
- Academic press:
- J Gen Virol (year: 2019, volume: 100(3), pages: 1633-1642), Publisher: Microbiology Society Journals
- Status:
- Published
- DOI:
- 10.1099/jgv.0.001225 – link to the publication
-
Next-Generation Sequencing of Hepatitis C Virus (HCV) Mixed-Genotype Infections in Anti-HCV-Negative Blood Donors.
- Authors:
- Janiak M, Caraballo Cortés K, Perlejewski K, Kubicka-Russel D, Grabarczyk P, Demkow U, Radkowski M.
- Academic press:
- Adv Exp Med Biol (year: 2018, volume: 1096:., pages: 65-71), Publisher: SPRINGER-VERLAG BERLIN.
- Status:
- Published
- DOI:
- 10.1007/5584_2018_190. – link to the publication
-
Next-generation sequencing analysis of a cluster of hepatitis C virus infections in a haematology and oncology center.
- Authors:
- Caraballo Cortes K, Rosińska M, Janiak M, Stępień M, Zagordi O, Perlejewski K, Osuch S, Pawełczyk A, Bukowska-Ośko I, Płoski R, Grabarczyk P, Laskus T, Radkowski M.
- Academic press:
- PlosONE (year: 2018, volume: Mar 22;13(3):, pages: e0194816.), Publisher: PUBLIC LIBRARY SCIENCE.
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0194816. – link to the publication