The impact of gene overexpression on selected fitness components in Saccharomyces cerevisiae

2013/11/B/NZ2/00122

Keywords

Descriptors

  • NZ2_1: Genetyka molekularna
  • NZ2_2: Genomika, transkryptomika i epigenomika
  • NZ2_3: Proteomika

Panel

NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution

Uniwersytet Jagielloński, Wydział Biologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Ryszard Korona

Number of co-investigators in the project: 2

Call

OPUS 6 – announced on 2013-09-16

Amount awarded
656 525 PLN
Project start date
2014-07-15
Project end date
2018-01-14
Project duration
42 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (4)

  1. Power provides protection: Genetic robustness in yeast depends on the capacity to generate energy

    Authors:
    Marcin Plech, Katarzyna Tomala, Hanna Tutaj, Dominika Ewa Piwcewicz, J. Arjan G. M. de Visser, Ryszard Korona
    Academic press:
    PLoS Genetics (year: 2017, volume: 2017, pages: 46039), Publisher: PLoS
    Status:
    Published
    DOI:
    link to the publication
  2. Strong dominance of functional alleles over gene deletions in both intensely growing and deeply starved yeast cells

    Authors:
    Agnieszka Marek i Ryszard Korona
    Academic press:
    Journal of Evolutionary Biology (year: 2016, volume: 29, pages: 1836-1845), Publisher: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1111/jeb.12917 – link to the publication
  3. An Overexpression Experiment Does Not Support the Hypothesis That Avoidance of Toxicity Determines the Rate of Protein Evolution

    Authors:
    Magdalena K. Biesiadecka, Piotr Sliwa, Katarzyna Tomala, and Ryszard Korona
    Academic press:
    Genome Biology and Evolution (year: 2020, volume: 12, pages: 589–596), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/gbe/evaa067 – link to the publication
  4. Gene overexpression screen for chromosome instability in yeast primarily identifies cell cycle progression genes

    Authors:
    Hanna Tutaj, Elzbieta Pogoda, Katarzyna Tomala, Ryszard Korona
    Academic press:
    Current Genetics (year: 2019, volume: 65, pages: 483–492), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00294-018-0885-x – link to the publication

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