Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Genome-wide characterization of type I IFN-induced transcriptomes and identification of novel ISGs and their antiviral functions

2013/11/B/NZ2/02569

Keywords:

RNA sequencing ChIP sequencing interferon biology alternative pathways novel gene functions

Descriptors:

  • NZ2_7: Bioinformatics
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Johannes Bluijssen (Bluyssen) 

Number of co-investigators in the project: 6

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 891 630 PLN

Project start date (Y-m-d): 2014-07-10

Project end date (Y-m-d): 2018-03-09

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. LCD monitor (2 szt.) (2 000 PLN)
  2. Komputer PC z systemem Windows 8 Professional (11 258 PLN)
  3. Zamrażarka niskotemperaturowa Panasonic.
  4. Aparat Real-Time PCR StepOne (50 000 PLN)
  5. Yasara structure (4 647 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. A positive feedback amplifier circuit that regulates ISG expression and controls type I and type II IFN responses
    Authors:
    Michalska A, Blaszczyk K, Wesoly J and Bluyssen HA
    Academic press:
    Frontiers in Immunology (rok: 2018, tom: 9, strony: 1135), Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fimmu.2018.01135. - link to the publication
  2. STAT2/IRF9 DIRECTS A PROLONGED ISGF3-LIKE TRANSCRIPTIONAL RESPONSE AND ANTIVIRAL ACTIVITY IN THE ABSENCE OF STAT1.
    Authors:
    Blaszczyk K, Olejnik A, Chen Y-L, Chmielewski S, Kostyrko K, Nowicka H, Ozgyin L, Wesoly J, Balint BL, Lee C-K, Bluyssen HA.
    Academic press:
    Biochemical Journal (rok: 2015, tom: 466(3), strony: 511-24), Wydawca: Portland press
    Status:
    Published
    DOI:
    10.1042/BJ20140644 - link to the publication
  3. The unique role of STAT2 in constitutive and IFN-induced transcription and antiviral responses
    Authors:
    Katarzyna Blaszczyk, Hanna Nowicka, Kaja Kostyrko, Aleksandra Antonczyk, Joanna Wesoly, Hans A.R. Bluyssen
    Academic press:
    Cytokine & Growth factor Reviews (rok: 2016, tom: 29, strony: 71-81), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10. - link to the publication

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