Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Mass transport of therapeutic substance from the homogeneous or multi-phase implant which is its reservoir or formation place.

2013/11/B/ST8/03672

Keywords:

bioprocess engineering diffusive transport with reaction controlled transport by polymeric structure implant hydrogel enzymatic reaction polymeric membrane local dosing of drugs

Descriptors:

  • ST8_1: Chemical engineering, technical chemistry, environmental engineering, sanitary engineering, engineering of chemical processes
  • ST6_12: Scientific computing, simulation and modelling tools

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Wrocławska, Wydział Chemiczny

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Anna Trusek-Hołownia 

Number of co-investigators in the project: 7

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 757 000 PLN

Project start date (Y-m-d): 2014-07-15

Project end date (Y-m-d): 2019-05-14

Project duration:: 58 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Pompa (19 000 PLN)
  2. Enkapsulator (130 000 PLN)
  3. Kolumna do HPLC (12 000 PLN)
  4. Spektrofotometr UV-Vis z komputerem do zczytywania i obróbki danych. (42 000 PLN)
  5. Laptop (5 000 PLN)
  6. Utratermostat z mieszadlem wielostanowiskowym (16 000 PLN)

Information in the final report

  • Publication in academic press/journals (11)
  • Book publications / chapters in book publications (1)
  1. Graphene oxide flake activation via divinylsulfone - a procedure for efficient beta-galactosidase immobilization.
    Authors:
    A.Trusek
    Academic press:
    Pol. J. Chem. Technol. (rok: 2019, tom: 21, strony: 27-32), Wydawca: Gunter
    Status:
    Published
    DOI:
    10.2478/pjct-2019-0006 - link to the publication
  2. Preparation and characterisation of gelatine hydrogels predisposed to use as matrices for effective immobilisation of biocatalysts
    Authors:
    K.Labus, A.Drozd, A.Trusek-Holownia
    Academic press:
    Chem. Papers (rok: 2016, tom: 70, strony: 523-530), Wydawca: Walter de Gruyter
    Status:
    Published
    DOI:
    10.1515/chempap-2015-0235 - link to the publication
  3. The membrane composite with silver nanoparticles for fibroblastic cell growth sustaining.
    Authors:
    M.Drabik, B.Kazimierczak, A.Grzeczkowicz, M.Antosiak-Iwanska, A.Kwiatkowska, L.Granicka
    Academic press:
    Des. Wat. Treat. (rok: 2018, tom: 101, strony: 70-76), Wydawca: Desalination Publications
    Status:
    Published
    DOI:
    10.5004/dwt2018.21796 - link to the publication
  4. 3D enzymatic preparations with graphene oxide flakes and hydrogel to obtain lactose-free products
    Authors:
    A.Trusek, D.Dworakowska, K.Czyzewska
    Academic press:
    Food and Bioproducts Processing (rok: 2020, tom: 121, strony: 224-229), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fbp.2020.03.002 - link to the publication
  5. Biodegradable polylactide and thermoplastic starch blends in drug release device - mass trasfer study.
    Authors:
    K.Labus, A.Trusek-Holownia, D.Semba, J.Ostrowska, P.Tynski, J.Bogusz
    Academic press:
    Pol. J. Chem. Technol. (rok: 2018, tom: 20, strony: 75-80), Wydawca: Gunter
    Status:
    Published
    DOI:
    10.2478/pjct-2018-0011 - link to the publication
  6. Polymeric drug carriers - Control of the daily dose and therapy duration
    Authors:
    A.Trusek-Holownia, P.Jaworska
    Academic press:
    Biocyber. Biomed. Eng. (rok: 2015, tom: 35, strony: 192-197), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbe.2014.11.001 - link to the publication
  7. Enzymatic hydrolysis of hyaluronic layer before drug dosing.
    Authors:
    A.Trusek, A.Niesobska, D.Semba
    Academic press:
    Curr. Pharm.Biotechnol. (rok: 2018, tom: 19, strony: 963-972), Wydawca: BENTHAM SCIENCE PUBL.
    Status:
    Published
    DOI:
    10.2174/1389201019666181017121811 - link to the publication
  8. Hydroliza enzymatyczna wiązania peptydowego z oporami dyfuzyjnymi
    Authors:
    Anita Niesobska, Anna Trusek-Hołownia
    Academic press:
    Inż. Apar. Chem. (rok: 2015, tom: 54, strony: 186-188), Wydawca: Simpress
    Status:
    Published
    DOI:
    brak - link to the publication
  9. Generation of homo- and heterogeneous microcapsules and their application.
    Authors:
    Damian Semba, Anna Trusek-Hołownia
    Academic press:
    Technic. Transact. (rok: 2017, tom: 114 (4), strony: 197-208), Wydawca: Politechnika Krakowska
    Status:
    Published
    DOI:
    10.4467/2353737XCT.17.060.6371 - link to the publication
  10. Graphene oxide as a potential drug carrier – Chemical carrier activation, drug attachment and its enzymatic controlled release
    Authors:
    A.Trusek, E.Kijak, L.Granicka
    Academic press:
    Materials Science and Engineering: C (rok: 2020, tom: 116, strony: 111240), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2020.111240 - link to the publication
  11. Drug carriers based on graphene oxide and hydrogel: opportunities and challenges in infection 2control tested by amoxicillin release
    Authors:
    Anna Trusek, Edward Kijak
    Academic press:
    Materials , Wydawca: MDPI
    Status:
    Submitted
    DOI:
    brak - link to the publication
  1. Kinetic studies of the hyaluronidase
    Authors:
    Anita Niesobska, Anna Trusek-Hołownia, Justyna Gamrat
    Book:
    Proceedings of Polish Conference of Chemical and Process Engineering (rok: 2016, tom: 1, strony: 1007-1015), Wydawca: Exall
    Status:
    Published

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